Stephen Tomlinson to Humans
This is a "connection" page, showing publications Stephen Tomlinson has written about Humans.
Connection Strength
0.605
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State of the science in inflammation and stroke recovery: A systematic review. Ann Phys Rehabil Med. 2022 Mar; 65(2):101546.
Score: 0.030
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Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System. Front Immunol. 2020; 11:566892.
Score: 0.028
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Anti-inflammatory and Neuroprotective Agents in Clinical Trials for CNS Disease and Injury: Where Do We Go From Here? Front Immunol. 2020; 11:2021.
Score: 0.028
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Complement-Dependent Synaptic Uptake and Cognitive Decline after Stroke and Reperfusion Therapy. J Neurosci. 2020 05 13; 40(20):4042-4058.
Score: 0.027
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Tissue-targeted complement therapeutics. Mol Immunol. 2018 10; 102:120-128.
Score: 0.024
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Acute Complement Inhibition Potentiates Neurorehabilitation and Enhances tPA-Mediated Neuroprotection. J Neurosci. 2018 07 18; 38(29):6527-6545.
Score: 0.024
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Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice. Hepatology. 2018 02; 67(2):721-735.
Score: 0.023
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Injury site-specific targeting of complement inhibitors for treating stroke. Immunol Rev. 2016 11; 274(1):270-280.
Score: 0.021
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Thromboembolic Model of Cerebral Ischemia and Reperfusion in Mice. Methods Mol Biol. 2016; 1462:357-72.
Score: 0.020
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Complementing regeneration. Oncotarget. 2015 Sep 08; 6(26):21769-70.
Score: 0.020
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Complement: an overview for the clinician. Hematol Oncol Clin North Am. 2015 Jun; 29(3):409-27.
Score: 0.019
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Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis. Clin Exp Immunol. 2015 Mar; 179(3):500-8.
Score: 0.019
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Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation. 2013 Mar 26; 127(12):1290-9.
Score: 0.017
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CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation. Adv Exp Med Biol. 2013; 735:137-54.
Score: 0.016
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A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. J Clin Invest. 2009 Aug; 119(8):2304-16.
Score: 0.013
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Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. Int J Cancer. 2008 Sep 15; 123(6):1357-63.
Score: 0.012
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Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer Res. 2008 Aug 15; 68(16):6734-42.
Score: 0.012
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Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. Cancer Res. 2007 Oct 01; 67(19):9535-41.
Score: 0.011
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Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. Am J Pathol. 2006 Sep; 169(3):1039-47.
Score: 0.011
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Defining the CD59-C9 binding interaction. J Biol Chem. 2006 Sep 15; 281(37):27398-404.
Score: 0.011
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Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. J Clin Invest. 2005 Sep; 115(9):2444-53.
Score: 0.010
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The effect of dexamethasone on human mucin 1 expression and antibody-dependent complement sensitivity in a prostate cancer cell line in vitro and in vivo. Immunology. 2004 Mar; 111(3):291-7.
Score: 0.009
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Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation. J Clin Invest. 2003 Jun; 111(12):1875-85.
Score: 0.008
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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis. Cell Rep. 2022 12 06; 41(10):111742.
Score: 0.008
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The role of complement in nonalcoholic fatty liver disease. Front Immunol. 2022; 13:1017467.
Score: 0.008
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A tumor-expressed inhibitor of the early but not late complement lytic pathway enhances tumor growth in a rat model of human breast cancer. Cancer Res. 2002 Feb 15; 62(4):1110-5.
Score: 0.008
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Modulation of the Complement System by Neoplastic Disease of the Central Nervous System. Front Immunol. 2021; 12:689435.
Score: 0.008
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In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries. Front Immunol. 2021; 12:630581.
Score: 0.007
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A novel injury site-natural antibody targeted complement inhibitor protects against lung transplant injury. Am J Transplant. 2021 06; 21(6):2067-2078.
Score: 0.007
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C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice. Front Immunol. 2020; 11:575154.
Score: 0.007
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Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease. Clin Cancer Res. 2020 07 01; 26(13):3481-3490.
Score: 0.007
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Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis. Cell Res. 2019 07; 29(7):548-561.
Score: 0.006
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CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma. Cell Death Dis. 2019 01 18; 10(2):52.
Score: 0.006
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Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. JCI Insight. 2018 12 20; 3(24).
Score: 0.006
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Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma. Mol Ther. 2018 10 03; 26(10):2379-2396.
Score: 0.006
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C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis. Mucosal Immunol. 2018 09; 11(5):1375-1385.
Score: 0.006
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Preclinical and Clinical Evidence on Ipsilateral Corticospinal Projections: Implication for Motor Recovery. Transl Stroke Res. 2017 12; 8(6):529-540.
Score: 0.006
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Surface Expression of TGF? Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer. Cancer Res. 2016 12 15; 76(24):7106-7117.
Score: 0.005
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Aberrant JMJD3 Expression Upregulates Slug to Promote Migration, Invasion, and Stem Cell-Like Behaviors in Hepatocellular Carcinoma. Cancer Res. 2016 11 15; 76(22):6520-6532.
Score: 0.005
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New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities. Semin Immunol. 2016 06; 28(3):260-7.
Score: 0.005
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A Rich-Club Organization in Brain Ischemia Protein Interaction Network. Sci Rep. 2015 Aug 27; 5:13513.
Score: 0.005
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Molecular Architecture of Spinal Cord Injury Protein Interaction Network. PLoS One. 2015; 10(8):e0135024.
Score: 0.005
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Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency. J Immunol. 2015 Aug 01; 195(3):1129-38.
Score: 0.005
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High USP22 expression indicates poor prognosis in hepatocellular carcinoma. Oncotarget. 2015 May 20; 6(14):12654-67.
Score: 0.005
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Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan; 116(1):102-14.
Score: 0.005
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Upregulation of the d opioid receptor in liver cancer promotes liver cancer progression both in vitro and in vivo. Int J Oncol. 2013 Oct; 43(4):1281-90.
Score: 0.004
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Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6877-82.
Score: 0.004
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The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes. Biochim Biophys Acta. 2012 Dec; 1821(12):1453-61.
Score: 0.004
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Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. J Biol Chem. 2011 Jun 10; 286(23):20952-62.
Score: 0.004
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A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement. Virol J. 2010 Jun 29; 7:142.
Score: 0.003
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A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitor. Virol J. 2010 Feb 09; 7:30.
Score: 0.003
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A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Adv Exp Med Biol. 2010; 703:137-49.
Score: 0.003
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Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. J Biol Chem. 2009 Jun 19; 284(25):16939-16947.
Score: 0.003
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App1: an antiphagocytic protein that binds to complement receptors 3 and 2. J Immunol. 2009 Jan 01; 182(1):84-91.
Score: 0.003
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Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. Mol Pharmacol. 2008 Sep; 74(3):574-84.
Score: 0.003
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Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment. Mol Immunol. 2008 May; 45(9):2570-80.
Score: 0.003
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Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex. Acta Crystallogr D Biol Crystallogr. 2007 Jun; 63(Pt 6):714-21.
Score: 0.003
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Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice. Cancer Res. 2006 Jun 15; 66(12):6258-63.
Score: 0.003
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Combined therapeutic use of AdGFPFasL and small molecule inhibitors of ceramide metabolism in prostate and head and neck cancers: a status report. Cancer Gene Ther. 2006 Dec; 13(12):1045-51.
Score: 0.003
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Cellular membrane type-1 matrix metalloproteinase (MT1-MMP) cleaves C3b, an essential component of the complement system. J Biol Chem. 2004 Nov 05; 279(45):46551-7.
Score: 0.002
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Complement function in mAb-mediated cancer immunotherapy. Trends Immunol. 2004 Mar; 25(3):158-64.
Score: 0.002
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A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans. Biochem J. 1997 Aug 01; 325 ( Pt 3):741-9.
Score: 0.001