Connection

Bryan Toole to Humans

This is a "connection" page, showing publications Bryan Toole has written about Humans.
Connection Strength

0.471
  1. The CD147-HYALURONAN Axis in Cancer. Anat Rec (Hoboken). 2020 06; 303(6):1573-1583.
    View in: PubMed
    Score: 0.026
  2. How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activity. Biosci Rep. 2015 Nov 24; 36(1):e00283.
    View in: PubMed
    Score: 0.020
  3. Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization. J Biol Chem. 2014 Feb 28; 289(9):5499-509.
    View in: PubMed
    Score: 0.018
  4. CD147: regulator of hyaluronan signaling in invasiveness and chemoresistance. Adv Cancer Res. 2014; 123:351-73.
    View in: PubMed
    Score: 0.018
  5. CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness. J Biol Chem. 2013 Sep 06; 288(36):26089-26104.
    View in: PubMed
    Score: 0.017
  6. CD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cells. Am J Pathol. 2013 Feb; 182(2):577-85.
    View in: PubMed
    Score: 0.016
  7. Regulation of invadopodia formation and activity by CD147. J Cell Sci. 2012 Feb 01; 125(Pt 3):777-88.
    View in: PubMed
    Score: 0.015
  8. Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides. Cancer Res. 2009 Jun 15; 69(12):4992-8.
    View in: PubMed
    Score: 0.013
  9. Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res. 2009 Feb 15; 69(4):1293-301.
    View in: PubMed
    Score: 0.012
  10. Targeting hyaluronan interactions in spinal cord astrocytomas and diffuse pontine gliomas. J Child Neurol. 2008 Oct; 23(10):1214-20.
    View in: PubMed
    Score: 0.012
  11. Hyaluronan oligosaccharides as a potential anticancer therapeutic. Curr Pharm Biotechnol. 2008 Aug; 9(4):249-52.
    View in: PubMed
    Score: 0.012
  12. Hyaluronan: a constitutive regulator of chemoresistance and malignancy in cancer cells. Semin Cancer Biol. 2008 Aug; 18(4):244-50.
    View in: PubMed
    Score: 0.012
  13. Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2. J Biol Chem. 2005 May 27; 280(21):20310-5.
    View in: PubMed
    Score: 0.010
  14. Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression. Thromb Haemost. 2005 Feb; 93(2):199-204.
    View in: PubMed
    Score: 0.009
  15. Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. J Biol Chem. 2005 Mar 11; 280(10):8875-83.
    View in: PubMed
    Score: 0.009
  16. Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions. Cells Tissues Organs. 2005; 179(1-2):66-72.
    View in: PubMed
    Score: 0.009
  17. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer. 2004 Jul; 4(7):528-39.
    View in: PubMed
    Score: 0.009
  18. Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production. Cancer Res. 2004 Feb 15; 64(4):1229-32.
    View in: PubMed
    Score: 0.009
  19. Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells. J Biol Chem. 2003 Nov 14; 278(46):45801-10.
    View in: PubMed
    Score: 0.009
  20. Regulation of multidrug resistance in cancer cells by hyaluronan. J Biol Chem. 2003 Jul 11; 278(28):25285-8.
    View in: PubMed
    Score: 0.008
  21. Perturbation of hyaluronan interactions inhibits malignant properties of glioma cells. Am J Pathol. 2003 May; 162(5):1403-9.
    View in: PubMed
    Score: 0.008
  22. Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome. Hum Genet. 2003 Jul; 113(2):178-87.
    View in: PubMed
    Score: 0.008
  23. Emmprin (CD147), a cell surface regulator of matrix metalloproteinase production and function. Curr Top Dev Biol. 2003; 54:371-89.
    View in: PubMed
    Score: 0.008
  24. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J Biol Chem. 2002 Oct 11; 277(41):38013-20.
    View in: PubMed
    Score: 0.008
  25. Hyaluronan-cell interactions in cancer and vascular disease. J Biol Chem. 2002 Feb 15; 277(7):4593-6.
    View in: PubMed
    Score: 0.008
  26. Hyaluronan in morphogenesis. Semin Cell Dev Biol. 2001 Apr; 12(2):79-87.
    View in: PubMed
    Score: 0.007
  27. Basigin (murine EMMPRIN) stimulates matrix metalloproteinase production by fibroblasts. J Cell Physiol. 2001 Mar; 186(3):371-9.
    View in: PubMed
    Score: 0.007
  28. Molecular characterization of a novel intracellular hyaluronan-binding protein. J Biol Chem. 2000 Sep 22; 275(38):29829-39.
    View in: PubMed
    Score: 0.007
  29. EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface. Cancer Res. 2000 Feb 15; 60(4):888-91.
    View in: PubMed
    Score: 0.007
  30. CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts. BMC Cancer. 2019 Sep 12; 19(1):912.
    View in: PubMed
    Score: 0.007
  31. Hyaluronan in morphogenesis. J Intern Med. 1997 Jul; 242(1):35-40.
    View in: PubMed
    Score: 0.006
  32. Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposi's sarcoma-associated herpesvirus. Oncotarget. 2016 Mar 01; 7(9):10459-71.
    View in: PubMed
    Score: 0.005
  33. CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells. Oncotarget. 2016 Jan 26; 7(4):3806-18.
    View in: PubMed
    Score: 0.005
  34. Induction of hyaluronan production by oncogenic KSHV and the contribution to viral pathogenesis in AIDS patients. Cancer Lett. 2015 Jul 01; 362(2):158-66.
    View in: PubMed
    Score: 0.005
  35. Cancer may be a pathway to cell survival under persistent hypoxia and elevated ROS: a model for solid-cancer initiation and early development. Int J Cancer. 2015 May 01; 136(9):2001-11.
    View in: PubMed
    Score: 0.005
  36. Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment. Cancer Res. 2013 Sep 01; 73(17):5347-59.
    View in: PubMed
    Score: 0.004
  37. Emmprin and KSHV: new partners in viral cancer pathogenesis. Cancer Lett. 2013 Sep 01; 337(2):161-6.
    View in: PubMed
    Score: 0.004
  38. Kaposi's sarcoma-associated herpesvirus suppression of DUSP1 facilitates cellular pathogenesis following de novo infection. J Virol. 2013 Jan; 87(1):621-35.
    View in: PubMed
    Score: 0.004
  39. Kaposi sarcoma-associated herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral fibroblasts. Cancer Lett. 2012 May 28; 318(2):214-20.
    View in: PubMed
    Score: 0.004
  40. KSHV activation of VEGF secretion and invasion for endothelial cells is mediated through viral upregulation of emmprin-induced signal transduction. Int J Cancer. 2012 Aug 15; 131(4):834-43.
    View in: PubMed
    Score: 0.004
  41. Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1201-7.
    View in: PubMed
    Score: 0.004
  42. Synthetic emmprin peptides with chitobiose substitution stimulate MMP-2 production by fibroblasts. BMC Cancer. 2011 Jul 17; 11:300.
    View in: PubMed
    Score: 0.004
  43. Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma. Leukemia. 2011 Oct; 25(10):1598-609.
    View in: PubMed
    Score: 0.004
  44. Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion. Int J Oncol. 2011 Sep; 39(3):657-64.
    View in: PubMed
    Score: 0.004
  45. Regulation of Nm23-H1 and cell invasiveness by Kaposi's sarcoma-associated herpesvirus. J Virol. 2011 Apr; 85(7):3596-606.
    View in: PubMed
    Score: 0.004
  46. Hyaluronan and its binding proteins, the hyaladherins. Curr Opin Cell Biol. 1990 Oct; 2(5):839-44.
    View in: PubMed
    Score: 0.004
  47. Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus. Cancer Res. 2010 May 15; 70(10):3884-9.
    View in: PubMed
    Score: 0.003
  48. Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug; 136(16):2825-35.
    View in: PubMed
    Score: 0.003
  49. The role and regulation of tumour-associated hyaluronan. Ciba Found Symp. 1989; 143:150-9; discussion 159-69, 281-5.
    View in: PubMed
    Score: 0.003
  50. Membrane association of the hyaluronate stimulatory factor from LX-1 human lung carcinoma cells. J Cell Biochem. 1988 Nov; 38(3):165-77.
    View in: PubMed
    Score: 0.003
  51. Hyaluronan regulates ceruloplasmin production by gliomas and their treatment-resistant multipotent progenitors. J Child Neurol. 2008 Oct; 23(10):1221-30.
    View in: PubMed
    Score: 0.003
  52. Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance. Drug Resist Updat. 2008 Jun; 11(3):110-21.
    View in: PubMed
    Score: 0.003
  53. Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells. J Biol Chem. 2008 May 23; 283(21):14335-44.
    View in: PubMed
    Score: 0.003
  54. Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts. Int J Cancer. 2007 Feb 15; 120(4):761-8.
    View in: PubMed
    Score: 0.003
  55. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J Biol Chem. 2006 Nov 17; 281(46):34936-41.
    View in: PubMed
    Score: 0.003
  56. Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mech Ageing Dev. 2006 Aug; 127(8):660-9.
    View in: PubMed
    Score: 0.003
  57. Extracellular matrix metalloproteinase inducer regulates metalloproteinases in human uterine endometrium. J Clin Endocrinol Metab. 2006 Jun; 91(6):2358-65.
    View in: PubMed
    Score: 0.003
  58. Extracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction. Circulation. 2006 Feb 14; 113(6):834-41.
    View in: PubMed
    Score: 0.003
  59. Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas. J Pathol. 2004 Mar; 202(3):341-51.
    View in: PubMed
    Score: 0.002
  60. Correlation of emmprin expression in vascular endothelial cells with blood-brain-barrier function: a study using magnetic resonance imaging enhanced by Gd-DTPA and immunohistochemistry in brain tumors. Virchows Arch. 2003 Jun; 442(6):577-84.
    View in: PubMed
    Score: 0.002
  61. Active site residues of cyclophilin A are crucial for its signaling activity via CD147. J Biol Chem. 2002 Jun 21; 277(25):22959-65.
    View in: PubMed
    Score: 0.002
  62. Developmental role of hyaluronate. Connect Tissue Res. 1982; 10(1):93-100.
    View in: PubMed
    Score: 0.002
  63. EMMPRIN-mediated MMP regulation in tumor and endothelial cells. Clin Exp Metastasis. 2002; 19(8):697-702.
    View in: PubMed
    Score: 0.002
  64. CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6360-5.
    View in: PubMed
    Score: 0.002
  65. Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer. 2000 Oct 01; 88(1):21-7.
    View in: PubMed
    Score: 0.002
  66. Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett. 2000 Sep 01; 157(2):177-84.
    View in: PubMed
    Score: 0.002
  67. Isolation and characterization of hyaluronidase from cultures of chick embryo skin- and muscle-derived fibroblasts. J Biol Chem. 1980 Feb 10; 255(3):1036-42.
    View in: PubMed
    Score: 0.002
  68. Expression of emmprin by oral squamous cell carcinoma. Int J Cancer. 2000 Feb 01; 85(3):347-52.
    View in: PubMed
    Score: 0.002
  69. Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions. J Histochem Cytochem. 1999 Dec; 47(12):1575-80.
    View in: PubMed
    Score: 0.002
  70. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett. 1998 Dec 11; 441(1):88-92.
    View in: PubMed
    Score: 0.002
  71. Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases. Gene. 1998 Oct 05; 220(1-2):99-108.
    View in: PubMed
    Score: 0.002
  72. Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. J Histochem Cytochem. 1997 May; 45(5):703-9.
    View in: PubMed
    Score: 0.001
  73. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem. 1997 Jan 03; 272(1):24-7.
    View in: PubMed
    Score: 0.001
  74. Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer. J Invest Dermatol. 1996 Jun; 106(6):1260-5.
    View in: PubMed
    Score: 0.001
  75. Extracellular events in limb development. Birth Defects Orig Artic Ser. 1974; 10(9):187-91.
    View in: PubMed
    Score: 0.001
  76. Hyaluronate in morphogenesis: inhibition of chondrogenesis in vitro. Proc Natl Acad Sci U S A. 1972 Jun; 69(6):1384-6.
    View in: PubMed
    Score: 0.001
  77. The cell surface hyaluronate binding sites of invasive human bladder carcinoma cells. Biochem Biophys Res Commun. 1987 Nov 30; 149(1):249-57.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.