Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Danyelle Townsend and Kenneth Tew.
Connection Strength

9.402
  1. Glutathione-s-transferases as determinants of cell survival and death. Antioxid Redox Signal. 2012 Dec 15; 17(12):1728-37.
    View in: PubMed
    Score: 0.420
  2. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313.
    View in: PubMed
    Score: 0.388
  3. Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification. Drug Metab Rev. 2011 May; 43(2):179-93.
    View in: PubMed
    Score: 0.384
  4. Redox platforms in cancer drug discovery and development. Curr Opin Chem Biol. 2011 Feb; 15(1):156-61.
    View in: PubMed
    Score: 0.376
  5. Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. Cancer Res. 2009 Oct 01; 69(19):7626-34.
    View in: PubMed
    Score: 0.348
  6. Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J Biol Chem. 2009 Jan 02; 284(1):436-445.
    View in: PubMed
    Score: 0.327
  7. Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
    View in: PubMed
    Score: 0.324
  8. NOV-002, a mimetic of glutathione disulfide. Expert Opin Investig Drugs. 2008 Jul; 17(7):1075-83.
    View in: PubMed
    Score: 0.319
  9. NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance. Cancer Res. 2008 Apr 15; 68(8):2870-7.
    View in: PubMed
    Score: 0.315
  10. A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. Mol Pharmacol. 2006 Feb; 69(2):501-8.
    View in: PubMed
    Score: 0.266
  11. Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
    View in: PubMed
    Score: 0.251
  12. Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. J Nutr. 2004 Nov; 134(11):3205S-3206S.
    View in: PubMed
    Score: 0.248
  13. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003 Oct 20; 22(47):7369-75.
    View in: PubMed
    Score: 0.231
  14. Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics. 2003; 3(3):157-72.
    View in: PubMed
    Score: 0.218
  15. Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.
    View in: PubMed
    Score: 0.214
  16. Cisplatin chemotherapy and renal function. Adv Cancer Res. 2021; 152:305-327.
    View in: PubMed
    Score: 0.194
  17. Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
    View in: PubMed
    Score: 0.191
  18. Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handb Exp Pharmacol. 2021; 264:71-91.
    View in: PubMed
    Score: 0.190
  19. Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma. Free Radic Biol Med. 2020 11 20; 160:755-767.
    View in: PubMed
    Score: 0.186
  20. Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone. J Pharmacol Exp Ther. 2020 08; 374(2):308-318.
    View in: PubMed
    Score: 0.183
  21. S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients. Sci Rep. 2019 09 24; 9(1):13792.
    View in: PubMed
    Score: 0.174
  22. Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 08 15; 79(16):4072-4085.
    View in: PubMed
    Score: 0.171
  23. Racial disparities, cancer and response to oxidative stress. Adv Cancer Res. 2019; 144:343-383.
    View in: PubMed
    Score: 0.169
  24. Pharmacology of ME-344, a novel cytotoxic isoflavone. Adv Cancer Res. 2019; 142:187-207.
    View in: PubMed
    Score: 0.167
  25. An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation. Free Radic Biol Med. 2018 05 20; 120:204-216.
    View in: PubMed
    Score: 0.157
  26. S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380.
    View in: PubMed
    Score: 0.155
  27. Redox Signaling and Bioenergetics Influence Lung Cancer Cell Line Sensitivity to the Isoflavone ME-344. J Pharmacol Exp Ther. 2016 08; 358(2):199-208.
    View in: PubMed
    Score: 0.138
  28. Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017 02 20; 26(6):247-261.
    View in: PubMed
    Score: 0.136
  29. Oxidative stress, redox regulation and diseases of cellular differentiation. Biochim Biophys Acta. 2015 Aug; 1850(8):1607-21.
    View in: PubMed
    Score: 0.124
  30. Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478.
    View in: PubMed
    Score: 0.123
  31. S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide. BBA Clin. 2014 Dec; 2:31-9.
    View in: PubMed
    Score: 0.122
  32. Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75.
    View in: PubMed
    Score: 0.117
  33. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504.
    View in: PubMed
    Score: 0.113
  34. Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility. Biochemistry. 2012 Oct 02; 51(39):7740-54.
    View in: PubMed
    Score: 0.107
  35. Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies. Biomed Pharmacother. 2012 Sep; 66(6):403-8.
    View in: PubMed
    Score: 0.105
  36. S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor a Stability and Function. Int J Cell Biol. 2012; 2012:273549.
    View in: PubMed
    Score: 0.104
  37. S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93.
    View in: PubMed
    Score: 0.103
  38. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 01; 15(1):233-70.
    View in: PubMed
    Score: 0.098
  39. Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One. 2010 Nov 30; 5(11):e14151.
    View in: PubMed
    Score: 0.094
  40. ABCA2 transporter deficiency reduces incidence of TRAMP prostate tumor metastasis and cellular chemotactic migration. Cancer Lett. 2011 Jan 28; 300(2):154-61.
    View in: PubMed
    Score: 0.094
  41. The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84.
    View in: PubMed
    Score: 0.094
  42. Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO. Invest New Drugs. 2011 Oct; 29(5):719-29.
    View in: PubMed
    Score: 0.090
  43. Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity. Biomed Pharmacother. 2010 Jan; 64(1):73-6.
    View in: PubMed
    Score: 0.087
  44. Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity. Biomed Pharmacother. 2009 Feb; 63(2):79-85.
    View in: PubMed
    Score: 0.081
  45. The ABCA2 transporter: intracellular roles in trafficking and metabolism of LDL-derived cholesterol and sterol-related compounds. Curr Drug Metab. 2007 Jan; 8(1):47-57.
    View in: PubMed
    Score: 0.072
  46. "Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol Cell Biol. 2007 Jan; 27(1):44-53.
    View in: PubMed
    Score: 0.071
  47. A novel role for human sulfiredoxin in the reversal of glutathionylation. Cancer Res. 2006 Jul 01; 66(13):6800-6.
    View in: PubMed
    Score: 0.070
  48. Evaluation of lipophilins as determinants of tumor cell response to estramustine. J Pharmacol Exp Ther. 2005 Dec; 315(3):1158-62.
    View in: PubMed
    Score: 0.066
  49. Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2). In Vivo. 2005 Jul-Aug; 19(4):657-60.
    View in: PubMed
    Score: 0.065
  50. Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol. 2004 May; 65(5):1070-9.
    View in: PubMed
    Score: 0.060
  51. Organosulfur compounds from alliaceae in the prevention of human pathologies. Biomed Pharmacother. 2004 Apr; 58(3):183-93.
    View in: PubMed
    Score: 0.059
  52. Sulfur containing amino acids and human disease. Biomed Pharmacother. 2004 Jan; 58(1):47-55.
    View in: PubMed
    Score: 0.058
  53. The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun; 57(3-4):145-55.
    View in: PubMed
    Score: 0.056
  54. Oxidative stress induces senescence in breast cancer stem cells. Biochem Biophys Res Commun. 2019 07 05; 514(4):1204-1209.
    View in: PubMed
    Score: 0.042
  55. A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities. PLoS One. 2019; 14(4):e0205626.
    View in: PubMed
    Score: 0.042
  56. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179.
    View in: PubMed
    Score: 0.039
  57. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase p. JCI Insight. 2016 Jun 02; 1(8).
    View in: PubMed
    Score: 0.035
  58. Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Mol Pharm. 2016 06 06; 13(6):2010-25.
    View in: PubMed
    Score: 0.034
  59. Glutathione S-transferase pi modulates NF-?B activation and pro-inflammatory responses in lung epithelial cells. Redox Biol. 2016 08; 8:375-82.
    View in: PubMed
    Score: 0.034
  60. Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem. 2016 Feb 26; 291(9):4763-78.
    View in: PubMed
    Score: 0.034
  61. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-? production by altering Nicastrin maturation and intracellular localization. J Biol Chem. 2012 Jan 06; 287(2):1100-11.
    View in: PubMed
    Score: 0.025
  62. Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity. Neuropsychopharmacology. 2011 Nov; 36(12):2551-60.
    View in: PubMed
    Score: 0.025
  63. PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J Med Chem. 2006 Feb 09; 49(3):1157-64.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.