Patrick Woster to Antimalarials
This is a "connection" page, showing publications Patrick Woster has written about Antimalarials.
Connection Strength
1.010
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Mechanism-based inhibitors of the aspartyl protease plasmepsin II as potential antimalarial agents. J Med Chem. 2010 May 27; 53(10):4234-47.
Score: 0.342
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New Transmission-Selective Antimalarial Agents through Hit-to-Lead Optimization of 2-([1,1'-Biphenyl]-4-carboxamido)benzoic Acid Derivatives. Chembiochem. 2022 Nov 04; 23(21):e202200427.
Score: 0.202
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Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations. Front Cell Infect Microbiol. 2019; 9:9.
Score: 0.157
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Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites. Bioorg Med Chem. 2015 Aug 15; 23(16):5131-43.
Score: 0.118
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Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds. Biochem Biophys Res Commun. 2012 May 11; 421(3):413-7.
Score: 0.097
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Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities. J Med Chem. 2011 Oct 13; 54(19):6624-33.
Score: 0.094