Patrick Woster to Cell Line, Tumor
This is a "connection" page, showing publications Patrick Woster has written about Cell Line, Tumor.
Connection Strength
0.602
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Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Eur J Med Chem. 2022 Dec 15; 244:114818.
Score: 0.143
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Use of polyamine derivatives as selective histone deacetylase inhibitors. Methods Mol Biol. 2011; 720:475-91.
Score: 0.063
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(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators. J Med Chem. 2010 Jul 22; 53(14):5197-212.
Score: 0.062
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Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors. J Med Chem. 2008 Apr 24; 51(8):2447-56.
Score: 0.052
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Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors. J Med Chem. 2005 Oct 06; 48(20):6350-65.
Score: 0.044
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Inhibition of Polyamine Biosynthesis Using Difluoromethylornithine Acts as a Potent Immune Modulator and Displays Therapeutic Synergy With PD-1-blockade. J Immunother. 2021 10 01; 44(8):283-291.
Score: 0.033
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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. PLoS One. 2018; 13(8):e0202677.
Score: 0.027
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Transcriptional activity of the islet ? cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem. 2015 Apr 10; 290(15):9812-22.
Score: 0.021
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Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism. Mol Cancer Ther. 2013 Oct; 12(10):2088-99.
Score: 0.019
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Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities. J Med Chem. 2011 Oct 13; 54(19):6624-33.
Score: 0.017
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Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells. Amino Acids. 2012 Feb; 42(2-3):529-38.
Score: 0.017
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Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids. 2012 Feb; 42(2-3):887-98.
Score: 0.017
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Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. Clin Cancer Res. 2009 Dec 01; 15(23):7217-28.
Score: 0.015
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A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2009 Oct 01; 69(19):7689-95.
Score: 0.015
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The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines. Cancer Chemother Pharmacol. 2010 May; 65(6):1067-81.
Score: 0.014
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Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. Proc Natl Acad Sci U S A. 2007 May 08; 104(19):8023-8.
Score: 0.012
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Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. J Biol Chem. 2005 Dec 02; 280(48):39843-51.
Score: 0.011
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Role of p53/p21(Waf1/Cip1) in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells. Cancer Biol Ther. 2005 Sep; 4(9):1006-13.
Score: 0.011
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Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells. Cancer Chemother Pharmacol. 2003 Nov; 52(5):383-90.
Score: 0.009