Patrick Woster to Antineoplastic Agents
This is a "connection" page, showing publications Patrick Woster has written about Antineoplastic Agents.
Connection Strength
2.191
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Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis. Eur J Med Chem. 2018 Mar 25; 148:210-220.
Score: 0.347
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(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators. J Med Chem. 2010 Jul 22; 53(14):5197-212.
Score: 0.206
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Recent advances in the development of polyamine analogues as antitumor agents. J Med Chem. 2009 Aug 13; 52(15):4551-73.
Score: 0.193
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Polyamine-based analogues as biochemical probes and potential therapeutics. Biochem Soc Trans. 2007 Apr; 35(Pt 2):356-63.
Score: 0.164
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Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors. J Med Chem. 2005 Oct 06; 48(20):6350-65.
Score: 0.148
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Significance of targeting polyamine metabolism as an antineoplastic strategy: unique targets for polyamine analogues. Proc West Pharmacol Soc. 2005; 48:24-30.
Score: 0.140
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The role of polyamine catabolism in anti-tumour drug response. Biochem Soc Trans. 2003 Apr; 31(2):361-5.
Score: 0.124
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Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs. Molecules. 2022 Jun 08; 27(12).
Score: 0.117
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Terminally alkylated polyamine analogues as chemotherapeutic agents. J Med Chem. 2001 Jan 04; 44(1):1-26.
Score: 0.106
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1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization. J Med Chem. 1999 Apr 22; 42(8):1415-21.
Score: 0.094
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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. PLoS One. 2018; 13(8):e0202677.
Score: 0.090
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Growth and biochemical effects of unsymmetrically substituted polyamine analogues in human lung tumor cells 1. Cancer Chemother Pharmacol. 1995; 36(1):69-74.
Score: 0.070
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Synthesis and evaluation of unsymmetrically substituted polyamine analogues as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents. J Med Chem. 1993 Oct 01; 36(20):2998-3004.
Score: 0.064
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Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm. BMC Cancer. 2010 Oct 14; 10:555.
Score: 0.052
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The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines. Cancer Chemother Pharmacol. 2010 May; 65(6):1067-81.
Score: 0.048
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Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. J Biol Chem. 2005 Dec 02; 280(48):39843-51.
Score: 0.037
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Cytotoxicity of novel unsymmetrically substituted inhibitors of polyamine biosynthesis in human cancer cells. J Cell Physiol. 2000 Feb; 182(2):209-13.
Score: 0.025
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Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells. Clin Cancer Res. 2000 Jan; 6(1):17-23.
Score: 0.025
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Unsymmetrically substituted polyamine analogue induces caspase-independent programmed cell death in Bcl-2-overexpressing cells. Cancer Res. 1998 Jul 01; 58(13):2711-4.
Score: 0.022
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The role of polyamine catabolism in polyamine analogue-induced programmed cell death. Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11557-62.
Score: 0.021
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Targeting polyamine metabolism for cancer therapy and prevention. Biochem J. 2016 10 01; 473(19):2937-53.
Score: 0.020
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Polyamine analogue induction of programmed cell death in human lung tumor cells. Clin Cancer Res. 1996 Mar; 2(3):441-6.
Score: 0.019
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Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue. Cancer Res. 1995 Aug 01; 55(15):3233-6.
Score: 0.018
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Polyamines and cancer: implications for chemotherapy and chemoprevention. Expert Rev Mol Med. 2013 Feb 22; 15:e3.
Score: 0.015
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Novel Pt(II) and Pd(II) complexes with polyamine analogues: synthesis and vibrational analysis. J Inorg Biochem. 2012 Mar; 108:1-7.
Score: 0.014
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Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment. Endocr Relat Cancer. 1999 Mar; 6(1):69-73.
Score: 0.006
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Structural specificity of polyamines and polyamine analogues in the protection of DNA from strand breaks induced by reactive oxygen species. Biochem Biophys Res Commun. 1998 Mar 06; 244(1):298-303.
Score: 0.005