Mariana Pehar to Animals
This is a "connection" page, showing publications Mariana Pehar has written about Animals.
Connection Strength
0.691
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
Score: 0.055
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Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration. Antioxid Redox Signal. 2018 06 20; 28(18):1652-1668.
Score: 0.045
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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602.
Score: 0.045
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Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis. Curr Pharm Des. 2017; 23(33):5010-5021.
Score: 0.043
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Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. Mol Cell Proteomics. 2016 Feb; 15(2):493-505.
Score: 0.040
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Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G??A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice. PLoS One. 2014; 9(7):e103438.
Score: 0.036
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P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion. Aging Cell. 2014 Jun; 13(3):449-56.
Score: 0.035
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Lysine acetylation in the lumen of the ER: a novel and essential function under the control of the UPR. Biochim Biophys Acta. 2013 Mar; 1833(3):686-97.
Score: 0.033
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SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway. J Biol Chem. 2012 Aug 24; 287(35):29921-30.
Score: 0.032
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Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death. Aging Cell. 2010 Apr; 9(2):174-90.
Score: 0.027
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Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J Neurosci. 2007 Jul 18; 27(29):7777-85.
Score: 0.022
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Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. Eur J Neurosci. 2006 Sep; 24(6):1575-80.
Score: 0.021
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Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons. Free Radic Biol Med. 2006 Dec 01; 41(11):1632-44.
Score: 0.021
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Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis. Neurodegener Dis. 2005; 2(3-4):139-46.
Score: 0.019
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
Score: 0.015
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Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J. 2021 02; 35(2):e21343.
Score: 0.014
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FABP7 upregulation induces a neurotoxic phenotype in astrocytes. Glia. 2020 12; 68(12):2693-2704.
Score: 0.014
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
Score: 0.013
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Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1. FASEB J. 2019 06; 33(6):7084-7091.
Score: 0.013
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Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice. Exp Neurol. 2018 04; 302:129-135.
Score: 0.012
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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1). J Biol Chem. 2016 May 13; 291(20):10836-46.
Score: 0.010
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Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Brain. 2016 Mar; 139(Pt 3):937-52.
Score: 0.010
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The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiol Aging. 2015 Oct; 36(10):2725-36.
Score: 0.010
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Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer. J Neurosci. 2014 May 14; 34(20):6772-89.
Score: 0.009
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Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study. Brain Res. 2013 May 01; 1508:1-8.
Score: 0.008
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Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation. J Biol Chem. 2012 Mar 09; 287(11):8424-33.
Score: 0.008
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AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability. J Cell Sci. 2010 Oct 01; 123(Pt 19):3378-88.
Score: 0.007
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Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiol Dis. 2010 Mar; 37(3):574-80.
Score: 0.007
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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J Neurosci Res. 2008 Dec; 86(16):3515-25.
Score: 0.006
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Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. J Neurosci. 2008 Apr 16; 28(16):4115-22.
Score: 0.006
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Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):740-5.
Score: 0.006
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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15038-43.
Score: 0.005
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Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. J Neurosci Res. 2006 Oct; 84(5):1098-106.
Score: 0.005
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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. J Neurochem. 2006 May; 97(3):687-96.
Score: 0.005
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Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem. 2005 Jul 08; 280(27):25571-9.
Score: 0.005
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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2005 Apr; 93(1):38-46.
Score: 0.005
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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev. 2004 Dec; 47(1-3):263-74.
Score: 0.005
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Stimulation of nerve growth factor expression in astrocytes by peroxynitrite. In Vivo. 2004 May-Jun; 18(3):269-74.
Score: 0.004
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Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo. 2004 May-Jun; 18(3):275-80.
Score: 0.004
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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2004 Apr; 89(2):464-73.
Score: 0.004
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Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors. Neurotox Res. 2003; 5(6):399-406.
Score: 0.004
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Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. J Neurosci Res. 2002 Jan 01; 67(1):21-9.
Score: 0.004