Marcelo Vargas to Motor Neurons
This is a "connection" page, showing publications Marcelo Vargas has written about Motor Neurons.
Connection Strength
3.272
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
Score: 0.658
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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1). J Biol Chem. 2016 May 13; 291(20):10836-46.
Score: 0.503
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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci. 2008 Dec 10; 28(50):13574-81.
Score: 0.304
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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. J Neurochem. 2006 May; 97(3):687-96.
Score: 0.251
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
Score: 0.191
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Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice. Exp Neurol. 2018 04; 302:129-135.
Score: 0.142
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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602.
Score: 0.137
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Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis. Curr Pharm Des. 2017; 23(33):5010-5021.
Score: 0.133
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Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Free Radic Biol Med. 2016 06; 95:112-20.
Score: 0.126
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Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J Neurosci. 2012 Dec 05; 32(49):17775-87.
Score: 0.100
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Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model. Neurobiol Dis. 2011 Sep; 43(3):543-51.
Score: 0.090
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Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes. Neurotherapeutics. 2010 Oct; 7(4):471-81.
Score: 0.086
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Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J Neurosci. 2007 Jul 18; 27(29):7777-85.
Score: 0.069
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Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. Eur J Neurosci. 2006 Sep; 24(6):1575-80.
Score: 0.065
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Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons. Free Radic Biol Med. 2006 Dec 01; 41(11):1632-44.
Score: 0.065
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Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem. 2005 Jul 08; 280(27):25571-9.
Score: 0.059
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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2005 Apr; 93(1):38-46.
Score: 0.059
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Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis. Neurodegener Dis. 2005; 2(3-4):139-46.
Score: 0.058
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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev. 2004 Dec; 47(1-3):263-74.
Score: 0.057
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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2004 Apr; 89(2):464-73.
Score: 0.055
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
Score: 0.043
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Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiol Dis. 2010 Mar; 37(3):574-80.
Score: 0.020