Marcelo Vargas to Amyotrophic Lateral Sclerosis
This is a "connection" page, showing publications Marcelo Vargas has written about Amyotrophic Lateral Sclerosis.
Connection Strength
6.816
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
Score: 0.767
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Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J. 2021 02; 35(2):e21343.
Score: 0.708
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
Score: 0.660
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Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis. Curr Pharm Des. 2017; 23(33):5010-5021.
Score: 0.534
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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1). J Biol Chem. 2016 May 13; 291(20):10836-46.
Score: 0.505
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Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. Mol Cell Proteomics. 2016 Feb; 15(2):493-505.
Score: 0.491
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Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G??A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice. PLoS One. 2014; 9(7):e103438.
Score: 0.450
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Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models. PLoS One. 2013; 8(2):e56625.
Score: 0.408
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Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model. Neurobiol Dis. 2011 Sep; 43(3):543-51.
Score: 0.360
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Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes. Neurotherapeutics. 2010 Oct; 7(4):471-81.
Score: 0.346
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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci. 2008 Dec 10; 28(50):13574-81.
Score: 0.305
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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J Neurosci Res. 2008 Dec; 86(16):3515-25.
Score: 0.305
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
Score: 0.171
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FABP7 upregulation induces a neurotoxic phenotype in astrocytes. Glia. 2020 12; 68(12):2693-2704.
Score: 0.170
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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602.
Score: 0.138
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Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Free Radic Biol Med. 2016 06; 95:112-20.
Score: 0.126
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Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiol Dis. 2010 Mar; 37(3):574-80.
Score: 0.081
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Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem. 2005 Jul 08; 280(27):25571-9.
Score: 0.059
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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2005 Apr; 93(1):38-46.
Score: 0.059
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Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis. Neurodegener Dis. 2005; 2(3-4):139-46.
Score: 0.058
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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev. 2004 Dec; 47(1-3):263-74.
Score: 0.058
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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2004 Apr; 89(2):464-73.
Score: 0.055