Marcelo Vargas to Animals
This is a "connection" page, showing publications Marcelo Vargas has written about Animals.
Connection Strength
0.888
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
Score: 0.060
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Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J. 2021 02; 35(2):e21343.
Score: 0.055
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FABP7 upregulation induces a neurotoxic phenotype in astrocytes. Glia. 2020 12; 68(12):2693-2704.
Score: 0.053
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
Score: 0.051
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Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1. FASEB J. 2019 06; 33(6):7084-7091.
Score: 0.048
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Redox Biology in Neurological Function, Dysfunction, and Aging. Antioxid Redox Signal. 2018 06 20; 28(18):1583-1586.
Score: 0.045
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Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice. Exp Neurol. 2018 04; 302:129-135.
Score: 0.044
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Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration. Antioxid Redox Signal. 2018 06 20; 28(18):1652-1668.
Score: 0.043
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Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis. Curr Pharm Des. 2017; 23(33):5010-5021.
Score: 0.041
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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1). J Biol Chem. 2016 May 13; 291(20):10836-46.
Score: 0.039
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Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. Mol Cell Proteomics. 2016 Feb; 15(2):493-505.
Score: 0.038
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Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G??A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice. PLoS One. 2014; 9(7):e103438.
Score: 0.035
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Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models. PLoS One. 2013; 8(2):e56625.
Score: 0.032
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Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model. Neurobiol Dis. 2011 Sep; 43(3):543-51.
Score: 0.028
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Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes. Neurotherapeutics. 2010 Oct; 7(4):471-81.
Score: 0.027
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The Nrf2-ARE cytoprotective pathway in astrocytes. Expert Rev Mol Med. 2009 Jun 03; 11:e17.
Score: 0.024
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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci. 2008 Dec 10; 28(50):13574-81.
Score: 0.024
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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J Neurosci Res. 2008 Dec; 86(16):3515-25.
Score: 0.024
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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. J Neurochem. 2006 May; 97(3):687-96.
Score: 0.020
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Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem. 2005 Jul 08; 280(27):25571-9.
Score: 0.018
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Stimulation of nerve growth factor expression in astrocytes by peroxynitrite. In Vivo. 2004 May-Jun; 18(3):269-74.
Score: 0.017
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
Score: 0.013
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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602.
Score: 0.011
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Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Free Radic Biol Med. 2016 06; 95:112-20.
Score: 0.010
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Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J Neurosci. 2012 Dec 05; 32(49):17775-87.
Score: 0.008
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Temporal patterns of tyrosine nitration in embryo heart development. Free Radic Biol Med. 2013 Feb; 55:101-8.
Score: 0.008
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Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. Toxicol Sci. 2010 Jun; 115(2):557-68.
Score: 0.006
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Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiol Dis. 2010 Mar; 37(3):574-80.
Score: 0.006
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Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2933-8.
Score: 0.006
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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. Ann N Y Acad Sci. 2008 Dec; 1147:61-9.
Score: 0.006
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Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J Neurosci. 2007 Jul 18; 27(29):7777-85.
Score: 0.005
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Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. J Neurosci Res. 2006 Oct; 84(5):1098-106.
Score: 0.005
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Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. Eur J Neurosci. 2006 Sep; 24(6):1575-80.
Score: 0.005
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Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons. Free Radic Biol Med. 2006 Dec 01; 41(11):1632-44.
Score: 0.005
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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2005 Apr; 93(1):38-46.
Score: 0.005
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Characterization of hypoxia induced gene 1: expression during rat central nervous system maturation and evidence of antisense RNA expression. Int J Dev Biol. 2005; 49(4):431-6.
Score: 0.005
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Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis. Neurodegener Dis. 2005; 2(3-4):139-46.
Score: 0.005
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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev. 2004 Dec; 47(1-3):263-74.
Score: 0.004
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Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo. 2004 May-Jun; 18(3):275-80.
Score: 0.004
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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem. 2004 Apr; 89(2):464-73.
Score: 0.004