Stephen Duncan to Hepatocyte Nuclear Factor 4
This is a "connection" page, showing publications Stephen Duncan has written about Hepatocyte Nuclear Factor 4.
Connection Strength
2.424
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A small-molecule screen reveals that HSP90? promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover. Development. 2017 05 15; 144(10):1764-1774.
Score: 0.581
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HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development. 2011 Oct; 138(19):4143-53.
Score: 0.394
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Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 2008 Oct; 48(4):1242-50.
Score: 0.323
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Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8419-24.
Score: 0.274
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Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology. 2006 Apr; 130(4):1207-20.
Score: 0.271
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Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J. 2007 Oct 31; 26(21):4445-56.
Score: 0.075
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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology. 2004 Apr; 39(4):1038-47.
Score: 0.059
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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet. 2003 Jul; 34(3):292-6.
Score: 0.056
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HNF4: a central regulator of hepatocyte differentiation and function. Hepatology. 2003 Jun; 37(6):1249-53.
Score: 0.056
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Generation of a conditionally null allele of hnf4alpha. Genesis. 2002 Feb; 32(2):130-3.
Score: 0.051
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Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 2000 Feb 15; 14(4):464-74.
Score: 0.044
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Regulation of a transcription factor network required for differentiation and metabolism. Science. 1998 Jul 31; 281(5377):692-5.
Score: 0.040
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The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13209-14.
Score: 0.038
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Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development. 1997 Jan; 124(2):279-87.
Score: 0.036
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Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7598-602.
Score: 0.030
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Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies. Stem Cell Res. 2012 Nov; 9(3):196-207.
Score: 0.026
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Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter. J Lipid Res. 2006 Jul; 47(7):1463-77.
Score: 0.017
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Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation. Dev Biol. 2005 Apr 01; 280(1):59-72.
Score: 0.016
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The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest. 2005 Apr; 115(4):1006-15.
Score: 0.016
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The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med. 2003 Feb; 9(2):220-4.
Score: 0.014
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Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 1994 Oct 15; 8(20):2466-77.
Score: 0.008