Stephen Duncan to Animals
This is a "connection" page, showing publications Stephen Duncan has written about Animals.
Connection Strength
1.233
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Advancements in Disease Modeling and Drug Discovery Using iPSC-Derived Hepatocyte-like Cells. Genes (Basel). 2022 03 24; 13(4).
Score: 0.059
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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells. Cell Rep. 2021 05 18; 35(7):109145.
Score: 0.055
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FoxA factors: the chromatin key and doorstop essential for liver development and function. Genes Dev. 2020 08 01; 34(15-16):1003-1004.
Score: 0.052
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A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep. 2018 11 06; 25(6):1469-1484.e5.
Score: 0.046
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Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery. J Vis Exp. 2018 05 19; (135).
Score: 0.045
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A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia. Cell Stem Cell. 2017 04 06; 20(4):478-489.e5.
Score: 0.042
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Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells. PLoS One. 2015; 10(8):e0136350.
Score: 0.037
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Engineering liver tissue from induced pluripotent stem cells: a first step in generating new organs for transplantation? Hepatology. 2013 Dec; 58(6):2198-201.
Score: 0.033
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HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development. 2011 Oct; 138(19):4143-53.
Score: 0.028
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Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum. BMC Dev Biol. 2010 Jun 02; 10:60.
Score: 0.026
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Organogenesis and development of the liver. Dev Cell. 2010 Feb 16; 18(2):175-89.
Score: 0.025
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Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology. 2010 Jan; 51(1):297-305.
Score: 0.025
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Transcriptional control of hepatocyte differentiation. Prog Mol Biol Transl Sci. 2010; 97:79-101.
Score: 0.025
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Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology. 2009 May; 49(5):1645-54.
Score: 0.024
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Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 2008 Oct; 48(4):1242-50.
Score: 0.023
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GATA4 is essential for jejunal function in mice. Gastroenterology. 2008 Nov; 135(5):1676-1686.e1.
Score: 0.023
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Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol. 2008 May 15; 317(2):614-9.
Score: 0.022
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Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem. 2007 Sep 21; 282(38):28137-48.
Score: 0.021
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Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol. 2007 Apr 23; 7:37.
Score: 0.021
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Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1. J Biol Chem. 2007 Apr 13; 282(15):11308-16.
Score: 0.021
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Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8419-24.
Score: 0.020
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Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol. 2006 Apr 12; 6:19.
Score: 0.019
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Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology. 2006 Apr; 130(4):1207-20.
Score: 0.019
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Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis. Biochem Soc Trans. 2005 Dec; 33(Pt 6):1534-6.
Score: 0.019
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Embryonic development of the liver. Hepatology. 2005 May; 41(5):956-67.
Score: 0.018
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GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol. 2005 Apr; 25(7):2622-31.
Score: 0.018
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GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12573-8.
Score: 0.017
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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology. 2004 Apr; 39(4):1038-47.
Score: 0.017
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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet. 2003 Jul; 34(3):292-6.
Score: 0.016
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HNF4: a central regulator of hepatocyte differentiation and function. Hepatology. 2003 Jun; 37(6):1249-53.
Score: 0.016
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Mechanisms controlling early development of the liver. Mech Dev. 2003 Jan; 120(1):19-33.
Score: 0.015
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Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination. Endocrine. 2002 Dec; 19(3):229-38.
Score: 0.015
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Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation. J Biol Chem. 2002 Nov 22; 277(47):45347-55.
Score: 0.015
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GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 08 01; 149(15).
Score: 0.015
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Generation of a conditionally null allele of hnf4alpha. Genesis. 2002 Feb; 32(2):130-3.
Score: 0.015
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Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation. BMC Biotechnol. 2001; 1:12.
Score: 0.014
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BMPs on the road to hepatogenesis. Genes Dev. 2001 Aug 01; 15(15):1879-84.
Score: 0.014
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An efficient method to successively introduce transgenes into a given genomic locus in the mouse. BMC Dev Biol. 2001; 1:10.
Score: 0.014
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The pancreas and its heartless beginnings. Nat Genet. 2001 Apr; 27(4):355-6.
Score: 0.014
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The murine Pes1 gene encodes a nuclear protein containing a BRCT domain. Genomics. 2000 Dec 01; 70(2):201-10.
Score: 0.013
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Transcriptional regulation of liver development. Dev Dyn. 2000 Oct; 219(2):131-42.
Score: 0.013
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Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 2000 Feb 15; 14(4):464-74.
Score: 0.013
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Regulation of a transcription factor network required for differentiation and metabolism. Science. 1998 Jul 31; 281(5377):692-5.
Score: 0.011
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The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13209-14.
Score: 0.011
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Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci. Cell Stem Cell. 2017 04 06; 20(4):558-570.e10.
Score: 0.010
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STAT signaling is active during early mammalian development. Dev Dyn. 1997 Feb; 208(2):190-8.
Score: 0.010
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Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development. 1997 Jan; 124(2):279-87.
Score: 0.010
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Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells. PLoS One. 2015; 10(8):e0134995.
Score: 0.009
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Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner. Exp Hematol. 2015 Jan; 43(1):53-64.e1-8.
Score: 0.009
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Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7598-602.
Score: 0.009
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Epicardial GATA factors regulate early coronary vascular plexus formation. Dev Biol. 2014 Feb 01; 386(1):204-15.
Score: 0.008
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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest. 2012 Oct; 122(10):3516-28.
Score: 0.008
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Vaccinia virus gene SalF5R is non-essential for virus replication in vitro and in vivo. J Gen Virol. 1992 May; 73 ( Pt 5):1235-42.
Score: 0.007
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A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. Mol Cell Proteomics. 2012 Aug; 11(8):303-16.
Score: 0.007
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Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice. Hepatology. 2012 Apr; 55(4):1070-82.
Score: 0.007
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The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med. 2011 Jun 12; 17(7):812-5.
Score: 0.007
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GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology. 2011 Apr; 140(4):1219-1229.e1-2.
Score: 0.007
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The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res. 2010 Oct 15; 107(8):1032-40.
Score: 0.007
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Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem. 2010 May 21; 285(21):16135-44.
Score: 0.006
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ER stress controls iron metabolism through induction of hepcidin. Science. 2009 Aug 14; 325(5942):877-80.
Score: 0.006
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Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells. J Biol Chem. 2008 Sep 26; 283(39):26468-76.
Score: 0.006
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Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007 Nov; 117(11):3198-210.
Score: 0.005
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Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J. 2007 Oct 31; 26(21):4445-56.
Score: 0.005
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Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. Anat Rec A Discov Mol Cell Evol Biol. 2006 Nov; 288(11):1216-24.
Score: 0.005
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Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development. Mech Dev. 2006 Dec; 123(12):869-80.
Score: 0.005
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A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A. 2006 Jul 25; 103(30):11189-94.
Score: 0.005
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Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter. J Lipid Res. 2006 Jul; 47(7):1463-77.
Score: 0.005
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Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res. 2006 Mar 31; 98(6):837-45.
Score: 0.005
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Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation. Dev Biol. 2005 Apr 01; 280(1):59-72.
Score: 0.005
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The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest. 2005 Apr; 115(4):1006-15.
Score: 0.004
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Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis. Circ Res. 2004 Apr 30; 94(8):1059-66.
Score: 0.004
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The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med. 2003 Feb; 9(2):220-4.
Score: 0.004
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Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice. Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10152-7.
Score: 0.003
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The vaccinia virus A4OR gene product is a nonstructural, type II membrane glycoprotein that is expressed at the cell surface. J Gen Virol. 1999 Aug; 80 ( Pt 8):2137-2148.
Score: 0.003
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In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos. Methods. 1998 Sep; 16(1):29-41.
Score: 0.003
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Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 1997 Apr 15; 11(8):1061-72.
Score: 0.003
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Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):923-7.
Score: 0.003
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Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6275-9.
Score: 0.002
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Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 1994 Oct 15; 8(20):2466-77.
Score: 0.002
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Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents. EMBO J. 1991 Dec; 10(13):4343-50.
Score: 0.002