Connection

Michael Ostrowski to Humans

This is a "connection" page, showing publications Michael Ostrowski has written about Humans.
Connection Strength

0.676
  1. Origin, activation and heterogeneity of fibroblasts associated with pancreas and breast cancers. Adv Cancer Res. 2022; 154:169-201.
    View in: PubMed
    Score: 0.031
  2. PTEN in cancer associated fibroblasts. Adv Cancer Res. 2022; 154:203-226.
    View in: PubMed
    Score: 0.031
  3. PTEN in the Stroma. Cold Spring Harb Perspect Med. 2019 10 01; 9(10).
    View in: PubMed
    Score: 0.026
  4. Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018 07 17; 9(1):2783.
    View in: PubMed
    Score: 0.024
  5. Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia. 2017 Jun; 19(6):496-508.
    View in: PubMed
    Score: 0.022
  6. The ETS family of oncogenic transcription factors in solid tumours. Nat Rev Cancer. 2017 06; 17(6):337-351.
    View in: PubMed
    Score: 0.022
  7. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017 04 20; 36(16):2297-2308.
    View in: PubMed
    Score: 0.021
  8. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia. 2016 09; 18(9):541-52.
    View in: PubMed
    Score: 0.021
  9. CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene. 2015 Jul; 34(28):3651-61.
    View in: PubMed
    Score: 0.018
  10. MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. PLoS One. 2014; 9(6):e100693.
    View in: PubMed
    Score: 0.018
  11. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. PLoS One. 2013; 8(8):e71533.
    View in: PubMed
    Score: 0.017
  12. Setting Snail2's pace during EMT. Nat Cell Biol. 2012 Nov; 14(11):1122-3.
    View in: PubMed
    Score: 0.016
  13. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2011 Dec 18; 14(2):159-67.
    View in: PubMed
    Score: 0.015
  14. Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Res. 2011 Feb 15; 71(4):1203-7.
    View in: PubMed
    Score: 0.014
  15. A new role for OPG: putting RANKL in its place. J Bone Miner Res. 2010 Sep; 25(9):1905-6.
    View in: PubMed
    Score: 0.014
  16. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Res. 2010 Feb 15; 70(4):1323-33.
    View in: PubMed
    Score: 0.013
  17. Genomic alterations in tumor stroma. Cancer Res. 2009 Sep 01; 69(17):6759-64.
    View in: PubMed
    Score: 0.013
  18. Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Mol Cell Biol. 2007 Jun; 27(11):4018-27.
    View in: PubMed
    Score: 0.011
  19. Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Mol Biol Cell. 2006 Sep; 17(9):3897-906.
    View in: PubMed
    Score: 0.010
  20. Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks. Crit Rev Eukaryot Gene Expr. 2006; 16(3):253-77.
    View in: PubMed
    Score: 0.010
  21. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. J Biol Chem. 2003 May 16; 278(20):17876-84.
    View in: PubMed
    Score: 0.008
  22. Cancer cachexia: involvement of an expanding macroenvironment. Cancer Cell. 2023 03 13; 41(3):581-584.
    View in: PubMed
    Score: 0.008
  23. The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer. Breast Cancer Res. 2021 06 12; 23(1):65.
    View in: PubMed
    Score: 0.007
  24. PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
    View in: PubMed
    Score: 0.007
  25. Targeting the KRAS a4-a5 allosteric interface inhibits pancreatic cancer tumorigenesis. Small GTPases. 2022 Jan; 13(1):114-127.
    View in: PubMed
    Score: 0.007
  26. Pten regulates collagen fibrillogenesis by fibroblasts through SPARC. PLoS One. 2021; 16(2):e0245653.
    View in: PubMed
    Score: 0.007
  27. Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain. Cancer Res. 2021 02 01; 81(3):606-618.
    View in: PubMed
    Score: 0.007
  28. Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition. BMB Rep. 2019 Oct; 52(10):595-600.
    View in: PubMed
    Score: 0.006
  29. Modeling Human Cancer-induced Cachexia. Cell Rep. 2019 08 06; 28(6):1612-1622.e4.
    View in: PubMed
    Score: 0.006
  30. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Res. 2019 08 15; 79(16):4124-4134.
    View in: PubMed
    Score: 0.006
  31. Nanofiber-expanded human CD34+ cells heal cutaneous wounds in streptozotocin-induced diabetic mice. Sci Rep. 2019 06 10; 9(1):8415.
    View in: PubMed
    Score: 0.006
  32. Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland. Neoplasia. 2019 01; 21(1):132-145.
    View in: PubMed
    Score: 0.006
  33. PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance. Nat Commun. 2018 11 27; 9(1):5006.
    View in: PubMed
    Score: 0.006
  34. Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair. Cell Res. 2018 11; 28(11):1090-1102.
    View in: PubMed
    Score: 0.006
  35. Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling. Mol Cell Biol. 1998 Sep; 18(9):5148-56.
    View in: PubMed
    Score: 0.006
  36. Activation of the ras-mitogen-activated protein kinase pathway and phosphorylation of ets-2 at position threonine 72 in human ovarian cancer cell lines. Cancer Res. 1998 May 15; 58(10):2253-9.
    View in: PubMed
    Score: 0.006
  37. Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent. Mol Cancer Res. 2018 07; 16(7):1092-1102.
    View in: PubMed
    Score: 0.006
  38. A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer. Breast Cancer Res Treat. 2018 Jun; 169(3):457-467.
    View in: PubMed
    Score: 0.006
  39. Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein. Genes Dev. 2017 09 15; 31(18):1847-1857.
    View in: PubMed
    Score: 0.006
  40. IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-?B. J Immunol. 2017 10 01; 199(7):2333-2342.
    View in: PubMed
    Score: 0.006
  41. Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Dev Cell. 2017 05 22; 41(4):392-407.e6.
    View in: PubMed
    Score: 0.006
  42. Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo. Sci Rep. 2017 05 11; 7(1):1787.
    View in: PubMed
    Score: 0.005
  43. Regulation of CSF-1 receptor expression. Mol Reprod Dev. 1997 Jan; 46(1):46-52; discussion 52-3.
    View in: PubMed
    Score: 0.005
  44. IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer. Gut. 2018 02; 67(2):320-332.
    View in: PubMed
    Score: 0.005
  45. The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling. Nucleic Acids Res. 1996 May 15; 24(10):1971-8.
    View in: PubMed
    Score: 0.005
  46. E2f3 in tumor macrophages promotes lung metastasis. Oncogene. 2016 07 14; 35(28):3636-46.
    View in: PubMed
    Score: 0.005
  47. Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling. Mol Cell Biol. 1995 Feb; 15(2):693-703.
    View in: PubMed
    Score: 0.005
  48. RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment. Cancer Res. 2015 Mar 15; 75(6):974-85.
    View in: PubMed
    Score: 0.005
  49. Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J Exp Med. 1994 Dec 01; 180(6):2309-19.
    View in: PubMed
    Score: 0.005
  50. Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. Mol Cancer Ther. 2015 Jan; 14(1):307-14.
    View in: PubMed
    Score: 0.005
  51. Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Cancer Res. 2014 Feb 01; 74(3):738-750.
    View in: PubMed
    Score: 0.004
  52. The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF). J Biol Chem. 2014 Jan 03; 289(1):326-34.
    View in: PubMed
    Score: 0.004
  53. Inhibitor ?B kinase 2 is a myosin light chain kinase in vascular smooth muscle. Circ Res. 2013 Aug 16; 113(5):562-70.
    View in: PubMed
    Score: 0.004
  54. Transcription factor ATF3 links host adaptive response to breast cancer metastasis. J Clin Invest. 2013 Jul; 123(7):2893-906.
    View in: PubMed
    Score: 0.004
  55. Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma. Mol Ther. 2013 Aug; 21(8):1517-25.
    View in: PubMed
    Score: 0.004
  56. MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro Oncol. 2013 Sep; 15(9):1212-24.
    View in: PubMed
    Score: 0.004
  57. SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility. J Clin Endocrinol Metab. 2013 May; 98(5):E973-80.
    View in: PubMed
    Score: 0.004
  58. Non-nuclear oncogenes and the regulation of gene expression in transformed cells. Crit Rev Oncog. 1993; 4(2):137-60.
    View in: PubMed
    Score: 0.004
  59. Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression. Mol Cell Biol. 1992 Dec; 12(12):5355-62.
    View in: PubMed
    Score: 0.004
  60. The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. Genes Dev. 1991 Oct; 5(10):1777-85.
    View in: PubMed
    Score: 0.004
  61. NF-?B signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol. 2011 Sep 01; 187(5):2740-7.
    View in: PubMed
    Score: 0.004
  62. Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol. 2011 Nov; 45(5):999-1006.
    View in: PubMed
    Score: 0.004
  63. A nuclear factor that binds to ras-responsive enhancer elements is present in human tumor cells. Cell Growth Differ. 1990 Dec; 1(12):601-6.
    View in: PubMed
    Score: 0.004
  64. TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy. PLoS One. 2010 Aug 30; 5(8):e12479.
    View in: PubMed
    Score: 0.003
  65. Transcriptional activation of a conserved sequence element by ras requires a nuclear factor distinct from c-fos or c-jun. Proc Natl Acad Sci U S A. 1990 May; 87(10):3866-70.
    View in: PubMed
    Score: 0.003
  66. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell. 2010 Mar 12; 37(5):620-32.
    View in: PubMed
    Score: 0.003
  67. Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments. J Math Biol. 2010 Sep; 61(3):401-21.
    View in: PubMed
    Score: 0.003
  68. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 2009 Oct 22; 461(7267):1084-91.
    View in: PubMed
    Score: 0.003
  69. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science. 2009 Aug 28; 325(5944):1142-6.
    View in: PubMed
    Score: 0.003
  70. The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma. PLoS One. 2009; 4(1):e4208.
    View in: PubMed
    Score: 0.003
  71. Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circ Res. 2009 Feb 27; 104(4):455-65.
    View in: PubMed
    Score: 0.003
  72. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res. 2008 Dec 15; 68(24):10257-66.
    View in: PubMed
    Score: 0.003
  73. PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. J Cell Physiol. 2008 Jun; 215(3):636-44.
    View in: PubMed
    Score: 0.003
  74. The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. J Immunol. 2008 May 15; 180(10):6733-42.
    View in: PubMed
    Score: 0.003
  75. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res. 2008 Feb 01; 68(3):937-45.
    View in: PubMed
    Score: 0.003
  76. CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. PLoS Genet. 2007 Sep; 3(9):1757-69.
    View in: PubMed
    Score: 0.003
  77. ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo. Cancer Res. 2007 May 01; 67(9):4364-72.
    View in: PubMed
    Score: 0.003
  78. The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. J Biol Chem. 2007 Jan 19; 282(3):1891-904.
    View in: PubMed
    Score: 0.003
  79. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Res. 2006 Aug 15; 66(16):8058-64.
    View in: PubMed
    Score: 0.003
  80. The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Hum Mol Genet. 2006 Sep 01; 15(17):2553-9.
    View in: PubMed
    Score: 0.003
  81. ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene. 2005 Jun 23; 24(27):4370-9.
    View in: PubMed
    Score: 0.002
  82. CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells. J Biol Chem. 2003 Dec 05; 278(49):49358-68.
    View in: PubMed
    Score: 0.002
  83. A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene. Mol Endocrinol. 2003 Jan; 17(1):11-26.
    View in: PubMed
    Score: 0.002
  84. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Hum Mol Genet. 2002 Jul 15; 11(15):1687-96.
    View in: PubMed
    Score: 0.002
  85. Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro. J Infect Dis. 2000 Dec; 182(6):1804-8.
    View in: PubMed
    Score: 0.002
  86. Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B. J Biol Chem. 1999 Sep 10; 274(37):26393-8.
    View in: PubMed
    Score: 0.002
  87. Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members. Genomics. 1999 Feb 15; 56(1):111-20.
    View in: PubMed
    Score: 0.002
  88. Evidence that human haematopoietic stem cells (HSC) do not reside within the CD34+KIT- cell population. Ann Transplant. 1999; 4(1):22-30.
    View in: PubMed
    Score: 0.002
  89. Control of interferon-tau gene expression by Ets-2. Proc Natl Acad Sci U S A. 1998 Jul 07; 95(14):7882-7.
    View in: PubMed
    Score: 0.001
  90. Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry. J Immunol. 1998 Apr 15; 160(8):3933-41.
    View in: PubMed
    Score: 0.001
  91. Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation. J Biol Chem. 1998 Mar 20; 273(12):6662-9.
    View in: PubMed
    Score: 0.001
  92. Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1. Mol Cell Biol. 1997 May; 17(5):2401-12.
    View in: PubMed
    Score: 0.001
  93. Transcriptional control of the expression of the c-fms gene encoding the receptor for macrophage colony-stimulating factor (CSF-1). Immunobiology. 1996 Oct; 195(4-5):461-76.
    View in: PubMed
    Score: 0.001
  94. Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. Mol Endocrinol. 1996 Sep; 10(9):1084-94.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.