Connection

John O'Bryan to Proto-Oncogene Proteins p21(ras)

This is a "connection" page, showing publications John O'Bryan has written about Proto-Oncogene Proteins p21(ras).
  1. Inhibition of RAS: proven and potential vulnerabilities. Biochem Soc Trans. 2020 10 30; 48(5):1831-1841.
    View in: PubMed
    Score: 0.687
  2. Targeting the a4-a5 interface of RAS results in multiple levels of inhibition. Small GTPases. 2019 09; 10(5):378-387.
    View in: PubMed
    Score: 0.564
  3. Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket. Proc Natl Acad Sci U S A. 2022 10 25; 119(43):e2204481119.
    View in: PubMed
    Score: 0.197
  4. Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun. 2021 05 11; 12(1):2656.
    View in: PubMed
    Score: 0.178
  5. Targeting the KRAS a4-a5 allosteric interface inhibits pancreatic cancer tumorigenesis. Small GTPases. 2022 Jan; 13(1):114-127.
    View in: PubMed
    Score: 0.178
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.