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Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism.
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Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism.
Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. J Biol Chem. 2005 Apr 29; 280(17):17196-202.
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PubMed
subject areas
Apoptosis
Caspase 7
Caspase 8
Caspase Inhibitors
Caspases
Cathepsin B
Cell Death
Cell Line, Tumor
Cysteine Endopeptidases
Cytosol
Dose-Response Relationship, Drug
Down-Regulation
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Enzyme Inhibitors
Humans
Immunoblotting
Lysosomes
Mass Spectrometry
Microscopy, Fluorescence
Phosphotransferases (Alcohol Group Acceptor)
Protein Binding
Recombinant Proteins
RNA, Small Interfering
Time Factors
Transfection
Tumor Necrosis Factor-alpha
authors with profiles
Yusuf A. Hannun