Denis Guttridge to Signal Transduction
This is a "connection" page, showing publications Denis Guttridge has written about Signal Transduction.
Connection Strength
3.175
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NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development. J Clin Invest. 2017 Oct 02; 127(10):3796-3809.
Score: 0.298
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Reining in nuclear factor-kappaB in skeletal muscle disorders. Curr Opin Clin Nutr Metab Care. 2013 May; 16(3):251-7.
Score: 0.220
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Mechanisms for maintaining muscle. Curr Opin Support Palliat Care. 2012 Dec; 6(4):451-6.
Score: 0.214
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Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab. 2012 Aug 08; 16(2):153-66.
Score: 0.208
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Making muscles grow by g protein-coupled receptor signaling. Sci Signal. 2011 Nov 29; 4(201):pe45.
Score: 0.199
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NF-?B signaling in skeletal muscle health and disease. Curr Top Dev Biol. 2011; 96:85-119.
Score: 0.187
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NF-kappaB signaling: a tale of two pathways in skeletal myogenesis. Physiol Rev. 2010 Apr; 90(2):495-511.
Score: 0.178
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Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. J Clin Invest. 2007 Apr; 117(4):889-901.
Score: 0.144
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Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome. Clin Cancer Res. 2007 Mar 01; 13(5):1356-61.
Score: 0.143
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Signaling pathways weigh in on decisions to make or break skeletal muscle. Curr Opin Clin Nutr Metab Care. 2004 Jul; 7(4):443-50.
Score: 0.119
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Emerging signaling mediators in the anorexia-cachexia syndrome of cancer. Trends Cancer. 2022 05; 8(5):397-403.
Score: 0.101
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The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage. Proc Natl Acad Sci U S A. 2019 09 03; 116(36):17980-17989.
Score: 0.085
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NF-?B inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nat Commun. 2018 08 24; 9(1):3431.
Score: 0.079
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Dysregulated Myogenesis in Rhabdomyosarcoma. Curr Top Dev Biol. 2018; 126:285-297.
Score: 0.075
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NF?B signaling in alveolar rhabdomyosarcoma. Dis Model Mech. 2017 09 01; 10(9):1109-1115.
Score: 0.074
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Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities. Mol Cancer Ther. 2017 02; 16(2):344-356.
Score: 0.070
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MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-?B. Cell Rep. 2016 10 04; 17(2):514-526.
Score: 0.070
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A TGF-? pathway associated with cancer cachexia. Nat Med. 2015 Nov; 21(11):1248-9.
Score: 0.065
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NF-?B functions in tumor initiation by suppressing the surveillance of both innate and adaptive immune cells. Cell Rep. 2014 Oct 09; 9(1):90-103.
Score: 0.061
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Disrupting cytokine signaling in pancreatic cancer: a phase I/II study of etanercept in combination with gemcitabine in patients with advanced disease. Pancreas. 2013 Jul; 42(5):813-8.
Score: 0.056
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IKKa and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism. J Cell Biol. 2012 Feb 20; 196(4):497-511.
Score: 0.051
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NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell. 2008 Nov 04; 14(5):369-81.
Score: 0.040
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IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. J Cell Biol. 2008 Feb 25; 180(4):787-802.
Score: 0.038
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Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention. Int Rev Immunol. 2008; 27(5):375-87.
Score: 0.038
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The effect of altered Toll-like receptor 4 signaling on cancer cachexia. Arch Otolaryngol Head Neck Surg. 2007 Dec; 133(12):1263-9.
Score: 0.038
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Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes. J Immunol. 2007 Nov 01; 179(9):6246-54.
Score: 0.038
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Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol. 2002 Apr 29; 157(3):429-40.
Score: 0.026
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Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling. J Biol Chem. 2001 Oct 19; 276(42):39259-63.
Score: 0.024
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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription. J Cell Biol. 2001 Jan 08; 152(1):87-96.
Score: 0.023
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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol Cell Biol. 2000 Mar; 20(5):1626-38.
Score: 0.022
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SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3798-E3807.
Score: 0.019
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Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia. Cancer Discov. 2016 09; 6(9):1036-51.
Score: 0.017
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Mechano-signalling pathways in an experimental intensive critical illness myopathy model. J Physiol. 2016 08 01; 594(15):4371-88.
Score: 0.017
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Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-?B-dependent Manner. Cancer Cell. 2016 Feb 08; 29(2):201-13.
Score: 0.017
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Microglia induce motor neuron death via the classical NF-?B pathway in amyotrophic lateral sclerosis. Neuron. 2014 Mar 05; 81(5):1009-1023.
Score: 0.015
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Regulation of skeletal muscle oxidative phenotype by classical NF-?B signalling. Biochim Biophys Acta. 2013 Aug; 1832(8):1313-25.
Score: 0.014
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Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA. Neuromuscul Disord. 2013 Feb; 23(2):188-91.
Score: 0.013
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NF-?B inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest. 2012 Jul; 122(7):2601-12.
Score: 0.013
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IKKa-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis. Blood. 2012 Jun 07; 119(23):5467-77.
Score: 0.013
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Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis. Mol Ther. 2012 Jun; 20(6):1222-33.
Score: 0.013
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IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma. Clin Cancer Res. 2011 May 01; 17(9):2757-66.
Score: 0.012
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Inhibition of the IKK/NF-?B pathway by AAV gene transfer improves muscle regeneration in older mdx mice. Gene Ther. 2010 Dec; 17(12):1476-83.
Score: 0.011
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The molecular mechanisms of skeletal muscle wasting: implications for therapy. Surgeon. 2006 Oct; 4(5):273-83.
Score: 0.009
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Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Mol Cell Biol. 2004 Jul; 24(13):5721-32.
Score: 0.007