CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.

CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model. J Immunol. 2008 Jul 15; 181(2):1063-70.

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subject areas

CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Cell Line, Tumor
Cytokines
Cytotoxicity, Immunologic
Epitopes
Genetic Vectors
Histocompatibility Antigens Class I
Humans
Melanoma
Neoplasm Proteins
Receptors, Antigen, T-Cell
Th1 Cells
Transduction, Genetic
Transgenes

authors with profiles

Shikhar Mehrotra