Connection

Wenjian Gan to Mechanistic Target of Rapamycin Complex 2

This is a "connection" page, showing publications Wenjian Gan has written about Mechanistic Target of Rapamycin Complex 2.
  1. DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway. Sci Signal. 2022 01 04; 15(715):eabh2290.
    View in: PubMed
    Score: 0.199
  2. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017 05 18; 545(7654):365-369.
    View in: PubMed
    Score: 0.036
  3. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell. 2016 06 16; 62(6):929-942.
    View in: PubMed
    Score: 0.034
  4. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015 Nov; 5(11):1194-209.
    View in: PubMed
    Score: 0.032
  5. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 2014 Apr 24; 508(7497):541-5.
    View in: PubMed
    Score: 0.029
  6. Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity. Protein Cell. 2014 Mar; 5(3):171-7.
    View in: PubMed
    Score: 0.029
  7. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2013 Nov; 15(11):1340-50.
    View in: PubMed
    Score: 0.028
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.