Connection

Wenjian Gan to Proto-Oncogene Proteins c-akt

This is a "connection" page, showing publications Wenjian Gan has written about Proto-Oncogene Proteins c-akt.
Connection Strength

2.480
  1. DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway. Sci Signal. 2022 01 04; 15(715):eabh2290.
    View in: PubMed
    Score: 0.675
  2. PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
    View in: PubMed
    Score: 0.649
  3. Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF. Nucleus. 2015; 6(4):261-5.
    View in: PubMed
    Score: 0.432
  4. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019 02; 21(2):226-237.
    View in: PubMed
    Score: 0.138
  5. pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science. 2016 08 26; 353(6302):929-32.
    View in: PubMed
    Score: 0.116
  6. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell. 2016 06 16; 62(6):929-942.
    View in: PubMed
    Score: 0.114
  7. Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Mol Cell. 2015 Feb 19; 57(4):648-661.
    View in: PubMed
    Score: 0.105
  8. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 2014 Apr 24; 508(7497):541-5.
    View in: PubMed
    Score: 0.098
  9. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2013 Nov; 15(11):1340-50.
    View in: PubMed
    Score: 0.096
  10. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017 05 18; 545(7654):365-369.
    View in: PubMed
    Score: 0.031
  11. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015 Nov; 5(11):1194-209.
    View in: PubMed
    Score: 0.027
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.