Wenjian Gan to Humans
This is a "connection" page, showing publications Wenjian Gan has written about Humans.
Connection Strength
0.244
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
Score: 0.029
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The Roles of Post-Translational Modifications on mTOR Signaling. Int J Mol Sci. 2021 Feb 11; 22(4).
Score: 0.029
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LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nat Cell Biol. 2020 02; 22(2):246-256.
Score: 0.027
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SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Mol Cell. 2015 Sep 17; 59(6):917-30.
Score: 0.020
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Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF. Nucleus. 2015; 6(4):261-5.
Score: 0.020
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Cell cycle status dictates effectiveness of rapamycin. Cell Cycle. 2015; 14(16):2556-7.
Score: 0.019
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Genetic fusions favor tumorigenesis through degron loss in oncogenes. Nat Commun. 2021 11 18; 12(1):6704.
Score: 0.008
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PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019 09; 9(9):1306-1323.
Score: 0.006
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Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1. Proc Natl Acad Sci U S A. 2019 05 07; 116(19):9423-9432.
Score: 0.006
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AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019 02; 21(2):226-237.
Score: 0.006
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SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019 02 11; 48(3):329-344.e5.
Score: 0.006
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K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair. Sci Signal. 2018 06 05; 11(533).
Score: 0.006
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The p85 isoform of the kinase S6K1 functions as a secreted oncoprotein to facilitate cell migration and tumor growth. Sci Signal. 2018 03 27; 11(523).
Score: 0.006
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The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nat Cell Biol. 2018 03; 20(3):320-331.
Score: 0.006
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Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nat Med. 2017 Sep; 23(9):1063-1071.
Score: 0.006
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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017 05 18; 545(7654):365-369.
Score: 0.006
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Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett. 2017 04 01; 390:11-20.
Score: 0.005
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Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Lett. 2017 01 28; 385:207-214.
Score: 0.005
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science. 2016 08 26; 353(6302):929-32.
Score: 0.005
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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell. 2016 06 16; 62(6):929-942.
Score: 0.005
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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015 Nov; 5(11):1194-209.
Score: 0.005
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Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Mol Cell. 2015 Feb 19; 57(4):648-661.
Score: 0.005
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Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity. Protein Cell. 2014 Mar; 5(3):171-7.
Score: 0.004
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Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2013 Nov; 15(11):1340-50.
Score: 0.004