Wenjian Gan to Mutation
This is a "connection" page, showing publications Wenjian Gan has written about Mutation.
Connection Strength
0.374
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
Score: 0.130
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Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Lett. 2017 01 28; 385:207-214.
Score: 0.094
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Genetic fusions favor tumorigenesis through degron loss in oncogenes. Nat Commun. 2021 11 18; 12(1):6704.
Score: 0.034
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SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019 02 11; 48(3):329-344.e5.
Score: 0.027
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Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett. 2017 04 01; 390:11-20.
Score: 0.024
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science. 2016 08 26; 353(6302):929-32.
Score: 0.023
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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015 Nov; 5(11):1194-209.
Score: 0.022
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Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nat Cell Biol. 2013 Nov; 15(11):1340-50.
Score: 0.019