Igor Roninson to Cyclin-Dependent Kinases
This is a "connection" page, showing publications Igor Roninson has written about Cyclin-Dependent Kinases.
Connection Strength
2.901
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Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition. Cells. 2019 11 09; 8(11).
Score: 0.666
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Identifying Cancers Impacted by CDK8/19. Cells. 2019 08 03; 8(8).
Score: 0.653
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CDK8/19 Mediator kinases potentiate induction of transcription by NF?B. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10208-10213.
Score: 0.572
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Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in?vitro and in?vivo. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2201073119.
Score: 0.201
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A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics. J Med Chem. 2022 02 24; 65(4):3420-3433.
Score: 0.194
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The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs. Cells. 2021 01 12; 10(1).
Score: 0.181
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Characterizing CDK8/19 Inhibitors through a NF?B-Dependent Cell-Based Assay. Cells. 2019 10 06; 8(10).
Score: 0.165
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Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer. Oncogene. 2018 08; 37(35):4792-4808.
Score: 0.150
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Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer. Curr Cancer Drug Targets. 2015; 15(8):739-49.
Score: 0.119