Igor Roninson to Antineoplastic Agents
This is a "connection" page, showing publications Igor Roninson has written about Antineoplastic Agents.
Connection Strength
1.422
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Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13799-804.
Score: 0.243
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Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements. Cancer Cell. 2003 Jul; 4(1):41-53.
Score: 0.129
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A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics. J Med Chem. 2022 02 24; 65(4):3420-3433.
Score: 0.117
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Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes. Cancer Biol Ther. 2002 Jan-Feb; 1(1):24-7.
Score: 0.117
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Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):389-94.
Score: 0.116
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Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene. 1999 Aug 26; 18(34):4808-18.
Score: 0.099
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A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Res. 1999 Aug 01; 59(15):3761-7.
Score: 0.099
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CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases. Cancer Res. 2018 12 01; 78(23):6594-6606.
Score: 0.093
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Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J Natl Cancer Inst. 1993 Apr 21; 85(8):632-9.
Score: 0.064
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Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3231-5.
Score: 0.064
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Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):7225-9.
Score: 0.053
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Agonist and antagonist of retinoic acid receptors cause similar changes in gene expression and induce senescence-like growth arrest in MCF-7 breast carcinoma cells. Cancer Res. 2006 Sep 01; 66(17):8749-61.
Score: 0.040
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Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in?vitro and in?vivo. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2201073119.
Score: 0.030
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Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response. Cancer Res. 2000 Sep 15; 60(18):5027-30.
Score: 0.027
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Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein. Int J Oncol. 2000 Sep; 17(3):579-86.
Score: 0.027
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A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication. Somat Cell Mol Genet. 1999 Jan; 25(1):9-26.
Score: 0.024
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Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer. Oncotarget. 2017 Feb 21; 8(8):12558-12575.
Score: 0.021
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Identification of p53 genetic suppressor elements which confer resistance to cisplatin. Oncogene. 1997 Jan 16; 14(2):185-93.
Score: 0.021
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Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function. Int J Cancer. 1996 Oct 09; 68(2):245-50.
Score: 0.020
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Molecular mechanism of multidrug resistance in tumor cells. Clin Physiol Biochem. 1987; 5(3-4):140-51.
Score: 0.010
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Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs. Princess Takamatsu Symp. 1983; 14:235-54.
Score: 0.008