Igor Roninson to Drug Resistance
This is a "connection" page, showing publications Igor Roninson has written about Drug Resistance.
Connection Strength
1.862
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Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3231-5.
Score: 0.102
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Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood. 1992 Dec 01; 80(11):2735-9.
Score: 0.100
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Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. Proc Natl Acad Sci U S A. 1992 Jul 01; 89(13):5824-8.
Score: 0.097
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From amplification to function: the case of the MDR1 gene. Mutat Res. 1992 May; 276(3):151-61.
Score: 0.096
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The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo. Biochem Pharmacol. 1992 Jan 09; 43(1):95-102.
Score: 0.094
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Activation of MDR1 (P-glycoprotein) gene expression in human cells by protein kinase C agonists. Oncol Res. 1992; 4(7):281-90.
Score: 0.094
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Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7386-90.
Score: 0.091
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Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. Cancer Res. 1991 May 15; 51(10):2720-6.
Score: 0.090
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Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci U S A. 1990 09; 87(18):7160-4.
Score: 0.085
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Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):7225-9.
Score: 0.085
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Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J Biol Chem. 1990 Jan 05; 265(1):506-14.
Score: 0.081
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An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell. 1988 May 20; 53(4):519-29.
Score: 0.073
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Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. Hum Genet. 1987 Oct; 77(2):142-4.
Score: 0.070
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Molecular mechanism of multidrug resistance in tumor cells. Clin Physiol Biochem. 1987; 5(3-4):140-51.
Score: 0.066
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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell. 1986 Nov 07; 47(3):381-9.
Score: 0.065
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Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4538-42.
Score: 0.064
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Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells. Nature. 1984 Jun 14-20; 309(5969):626-8.
Score: 0.055
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A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication. Somat Cell Mol Genet. 1999 Jan; 25(1):9-26.
Score: 0.038
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Internal ribosomal entry site-containing retroviral vectors with green fluorescent protein and drug resistance markers. Hum Gene Ther. 1998 May 20; 9(8):1233-6.
Score: 0.036
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Genetic suppressor elements: new tools for molecular oncology--thirteenth Cornelius P. Rhoads Memorial Award Lecture. Cancer Res. 1995 Sep 15; 55(18):4023-8.
Score: 0.030
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Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators. Biochemistry. 1995 Jan 10; 34(1):32-9.
Score: 0.029
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Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3744-8.
Score: 0.027
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MDR-1 expression in metastatic malignant melanoma. J Surg Res. 1993 Jun; 54(6):621-4.
Score: 0.026
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Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J Natl Cancer Inst. 1993 Apr 21; 85(8):632-9.
Score: 0.026
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Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas. J Natl Cancer Inst. 1992 Oct 07; 84(19):1486-91.
Score: 0.025
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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell. 1991 Jul 12; 66(1):85-94.
Score: 0.023
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Structure and expression of the human MDR (P-glycoprotein) gene family. Mol Cell Biol. 1989 Sep; 9(9):3808-20.
Score: 0.020
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Detection of multidrug resistance markers, P-glycoprotein and mdr1 mRNA, in human leukemia cells. Jpn J Cancer Res. 1987 Dec; 78(12):1415-9.
Score: 0.018
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Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA. Mol Cell Biol. 1987 Dec; 7(12):4549-52.
Score: 0.018
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RFLPs associated with MDR2, a member of the human multidrug resistance gene family mapped to chromosome 7. Nucleic Acids Res. 1987 Aug 11; 15(15):6305.
Score: 0.017
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The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation. J Biol Chem. 1987 Jan 15; 262(2):505-8.
Score: 0.017
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The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. Biochem Biophys Res Commun. 1986 Dec 30; 141(3):956-62.
Score: 0.017
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Detection of amplified sequences in mammalian DNA by in-gel renaturation and SINE hybridization. Somat Cell Mol Genet. 1986 Nov; 12(6):611-23.
Score: 0.016
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Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene. Mol Cell Biol. 1986 Nov; 6(11):4039-45.
Score: 0.016
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Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science. 1986 May 02; 232(4750):643-5.
Score: 0.016
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Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells. Proc Natl Acad Sci U S A. 1986 Jan; 83(2):337-41.
Score: 0.015
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Resistance to taxol chemotherapy produced in mouse marrow cells by safety-modified retroviruses containing a human MDR-1 transcription unit. Gene Ther. 1995 Jun; 2(4):279-84.
Score: 0.007
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Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein. Int J Cancer. 1993 Sep 30; 55(3):478-84.
Score: 0.007
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Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line. Mol Cell Biol. 1989 Jan; 9(1):109-15.
Score: 0.005
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Localization of multidrug resistance-associated DNA sequences to human chromosome 7. Somat Cell Mol Genet. 1986 Jul; 12(4):415-20.
Score: 0.004
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Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs. Princess Takamatsu Symp. 1983; 14:235-54.
Score: 0.003