Igor Roninson to Doxorubicin
This is a "connection" page, showing publications Igor Roninson has written about Doxorubicin.
Connection Strength
0.493
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p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation. Oncogene. 2007 Oct 18; 26(48):6954-8.
Score: 0.066
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p21 (CDKN1A) is a negative regulator of p53 stability. Cell Cycle. 2007 Jun 15; 6(12):1468-71.
Score: 0.066
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Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1. Cancer Res. 2005 Oct 01; 65(19):8927-35.
Score: 0.059
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Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):389-94.
Score: 0.045
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Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene. 1999 Aug 26; 18(34):4808-18.
Score: 0.039
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A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Res. 1999 Aug 01; 59(15):3761-7.
Score: 0.039
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A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication. Somat Cell Mol Genet. 1999 Jan; 25(1):9-26.
Score: 0.037
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Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function. Int J Cancer. 1996 Oct 09; 68(2):245-50.
Score: 0.032
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Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis. Cancer Lett. 1996 Oct 01; 107(1):73-81.
Score: 0.032
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An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell. 1988 May 20; 53(4):519-29.
Score: 0.018
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Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene. Mol Cell Biol. 1986 Nov; 6(11):4039-45.
Score: 0.016
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Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4538-42.
Score: 0.015
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Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells. Nature. 1984 Jun 14-20; 309(5969):626-8.
Score: 0.013
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Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA. Mol Cell Biol. 1987 Dec; 7(12):4549-52.
Score: 0.004
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The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation. J Biol Chem. 1987 Jan 15; 262(2):505-8.
Score: 0.004
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The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. Biochem Biophys Res Commun. 1986 Dec 30; 141(3):956-62.
Score: 0.004
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Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science. 1986 May 02; 232(4750):643-5.
Score: 0.004