Connection

Robert Haile to Genetic Predisposition to Disease

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This is a "connection" page, showing publications Robert Haile has written about Genetic Predisposition to Disease.
Robert Haile
Connection Strength
4.856
Genetic Predisposition to Disease
  1. Genetic variation in insulin pathway genes and distal colorectal adenoma risk. Int J Colorectal Dis. 2012 Dec; 27(12):1587-95.
    View in: PubMed
    Score: 0.307
  2. Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry. Cancer Prev Res (Phila). 2012 Feb; 5(2):328-35.
    View in: PubMed
    Score: 0.296
  3. Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):525-36.
    View in: PubMed
    Score: 0.260
  4. Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):89-100.
    View in: PubMed
    Score: 0.259
  5. Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control. 2010 Apr; 21(4):597-608.
    View in: PubMed
    Score: 0.259
  6. Breast cancer risks for BRCA1/2 carriers. Science. 2004 Dec 24; 306(5705):2187-91; author reply 2187-91.
    View in: PubMed
    Score: 0.183
  7. Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 05; 30(5):895-903.
    View in: PubMed
    Score: 0.140
  8. Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome. Br J Cancer. 2019 11; 121(10):869-876.
    View in: PubMed
    Score: 0.127
  9. DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility. Int J Cancer. 2020 01 15; 146(2):363-372.
    View in: PubMed
    Score: 0.125
  10. Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet. 2019 01; 51(1):76-87.
    View in: PubMed
    Score: 0.120
  11. Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Int J Cancer. 2017 06 15; 140(12):2728-2733.
    View in: PubMed
    Score: 0.107
  12. Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2017 03; 26(3):404-412.
    View in: PubMed
    Score: 0.104
  13. Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants. PLoS One. 2016; 11(7):e0157521.
    View in: PubMed
    Score: 0.102
  14. Childhood cancers in families with and without Lynch syndrome. Fam Cancer. 2015 Dec; 14(4):545-51.
    View in: PubMed
    Score: 0.098
  15. Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Sci Rep. 2015 12 01; 5:17369.
    View in: PubMed
    Score: 0.098
  16. A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1. Hum Genet. 2015 Nov; 134(11-12):1249-1262.
    View in: PubMed
    Score: 0.096
  17. Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015 Jul 07; 6:7138.
    View in: PubMed
    Score: 0.095
  18. Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun. 2014 Aug 08; 5:4613.
    View in: PubMed
    Score: 0.089
  19. A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study. Carcinogenesis. 2014 Nov; 35(11):2512-9.
    View in: PubMed
    Score: 0.089
  20. Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut. 2014 May; 63(5):800-7.
    View in: PubMed
    Score: 0.083
  21. Common variants in genes coding for chemotherapy metabolizing enzymes, transporters, and targets: a case-control study of contralateral breast cancer risk in the WECARE Study. Cancer Causes Control. 2013 Aug; 24(8):1605-14.
    View in: PubMed
    Score: 0.082
  22. Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry. PLoS One. 2013; 8(4):e60464.
    View in: PubMed
    Score: 0.081
  23. Folate-genetics and colorectal neoplasia: what we know and need to know next. Mol Nutr Food Res. 2013 Apr; 57(4):607-27.
    View in: PubMed
    Score: 0.080
  24. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology. 2013 Apr; 144(4):799-807.e24.
    View in: PubMed
    Score: 0.080
  25. cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue. PLoS One. 2012; 7(2):e30477.
    View in: PubMed
    Score: 0.075
  26. Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol. 2012 Mar 20; 30(9):958-64.
    View in: PubMed
    Score: 0.075
  27. Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study. Breast Cancer Res. 2011; 13(6):R114.
    View in: PubMed
    Score: 0.074
  28. Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer. Prostaglandins Other Lipid Mediat. 2012 Jan; 97(1-2):22-8.
    View in: PubMed
    Score: 0.072
  29. Body mass index in early adulthood and endometrial cancer risk for mismatch repair gene mutation carriers. Obstet Gynecol. 2011 Apr; 117(4):899-905.
    View in: PubMed
    Score: 0.071
  30. Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study. Cancer Causes Control. 2011 Apr; 22(4):541-52.
    View in: PubMed
    Score: 0.070
  31. Risk of contralateral breast cancer associated with common variants in BRCA1 and BRCA2: potential modifying effect of BRCA1/BRCA2 mutation carrier status. Breast Cancer Res Treat. 2011 Jun; 127(3):819-29.
    View in: PubMed
    Score: 0.069
  32. Parent of origin effects on age at colorectal cancer diagnosis. Int J Cancer. 2010 Jul 15; 127(2):361-6.
    View in: PubMed
    Score: 0.067
  33. A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1812-21.
    View in: PubMed
    Score: 0.067
  34. The association of tumor microsatellite instability phenotype with family history of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3):967-75.
    View in: PubMed
    Score: 0.061
  35. Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study. Gastroenterology. 2009 Apr; 136(4):1251-60.
    View in: PubMed
    Score: 0.060
  36. BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1863-70.
    View in: PubMed
    Score: 0.052
  37. Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet. 2023 01; 55(1):89-99.
    View in: PubMed
    Score: 0.040
  38. Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history. Fam Cancer. 2019 10; 18(4):389-397.
    View in: PubMed
    Score: 0.032
  39. Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer. JAMA Netw Open. 2019 09 04; 2(9):e1912259.
    View in: PubMed
    Score: 0.032
  40. Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database. Genet Med. 2020 01; 22(1):15-25.
    View in: PubMed
    Score: 0.031
  41. Association of Common Genetic Variants With Contralateral Breast Cancer Risk in the WECARE Study. J Natl Cancer Inst. 2017 10 01; 109(10).
    View in: PubMed
    Score: 0.028
  42. Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. PLoS Genet. 2016 Oct; 12(10):e1006296.
    View in: PubMed
    Score: 0.026
  43. CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk. Br J Cancer. 2016 Jan 19; 114(2):221-9.
    View in: PubMed
    Score: 0.025
  44. Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carcinogenesis. 2015 Sep; 36(9):999-1007.
    View in: PubMed
    Score: 0.024
  45. Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry. JAMA Oncol. 2015 May; 1(2):214-21.
    View in: PubMed
    Score: 0.023
  46. Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history. Cancer Epidemiol Biomarkers Prev. 2015 Mar; 24(3):512-519.
    View in: PubMed
    Score: 0.023
  47. A randomized trial to increase colonoscopy screening in members of high-risk families in the colorectal cancer family registry and cancer genetics network. Cancer Epidemiol Biomarkers Prev. 2014 Apr; 23(4):601-10.
    View in: PubMed
    Score: 0.022
  48. A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev. 2014 Apr; 23(4):658-69.
    View in: PubMed
    Score: 0.022
  49. Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer. Gastroenterology. 2014 May; 146(5):1208-11.e1-5.
    View in: PubMed
    Score: 0.021
  50. Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2094-101.
    View in: PubMed
    Score: 0.021
  51. Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans. Hum Mol Genet. 2013 Dec 15; 22(24):5048-55.
    View in: PubMed
    Score: 0.021
  52. Diagnostic chest X-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev. 2013 Sep; 22(9):1547-56.
    View in: PubMed
    Score: 0.021
  53. Contralateral breast cancer after radiotherapy among BRCA1 and BRCA2 mutation carriers: a WECARE study report. Eur J Cancer. 2013 Sep; 49(14):2979-85.
    View in: PubMed
    Score: 0.021
  54. Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? Eur J Cancer. 2013 May; 49(7):1578-87.
    View in: PubMed
    Score: 0.020
  55. Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Hum Genet. 2012 Oct; 131(10):1565-89.
    View in: PubMed
    Score: 0.019
  56. Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22. PLoS One. 2012; 7(5):e38175.
    View in: PubMed
    Score: 0.019
  57. Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study. Hum Mutat. 2012 Jan; 33(1):158-64.
    View in: PubMed
    Score: 0.018
  58. Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet. 2012 Feb; 131(2):217-34.
    View in: PubMed
    Score: 0.018
  59. Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma. Int J Cancer. 2010 Dec 01; 127(11):2678-84.
    View in: PubMed
    Score: 0.017
  60. Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22. Cancer Res. 2010 Jul 01; 70(13):5409-18.
    View in: PubMed
    Score: 0.017
  61. Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2. J Clin Oncol. 2010 May 10; 28(14):2404-10.
    View in: PubMed
    Score: 0.017
  62. Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study. J Natl Cancer Inst. 2010 Apr 07; 102(7):475-83.
    View in: PubMed
    Score: 0.016
  63. Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res. 2010 Apr 01; 16(7):2214-24.
    View in: PubMed
    Score: 0.016
  64. Oral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study. Breast Cancer Res Treat. 2010 Feb; 120(1):175-83.
    View in: PubMed
    Score: 0.016
  65. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3208-15.
    View in: PubMed
    Score: 0.015
  66. Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res. 2007 Dec 01; 67(23):11128-32.
    View in: PubMed
    Score: 0.014
  67. Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2331-43.
    View in: PubMed
    Score: 0.014
  68. Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study. Breast Cancer Res. 2004; 6(3):R199-214.
    View in: PubMed
    Score: 0.011
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