Michael Wyatt to Humans
This is a "connection" page, showing publications Michael Wyatt has written about Humans.
Connection Strength
0.365
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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells. J Med Chem. 2021 07 22; 64(14):9916-9925.
Score: 0.030
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Microbes as Drugs: The Potential of Pharmabiotics. Pharmacotherapy. 2020 02; 40(2):102-106.
Score: 0.027
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Potential unintended consequences of getting rigorous with scientific rigor. Carcinogenesis. 2018 01 12; 39(1):26-27.
Score: 0.023
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Human Papillomavirus Type 16 L2 DNA Methylation in Exfoliated Cervical Cells From College-Age Women. J Low Genit Tract Dis. 2016 10; 20(4):332-7.
Score: 0.021
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Advances in understanding the coupling of DNA base modifying enzymes to processes involving base excision repair. Adv Cancer Res. 2013; 119:63-106.
Score: 0.017
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SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. Mutat Res. 2013 Mar-Apr; 743-744:26-32.
Score: 0.016
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Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype. Mol Cancer Ther. 2012 Aug; 11(8):1683-92.
Score: 0.016
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Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics. Biochem Pharmacol. 2012 Mar 15; 83(6):741-6.
Score: 0.015
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PLK1 as an oncology target: current status and future potential. Drug Discov Today. 2011 Jul; 16(13-14):619-25.
Score: 0.015
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Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 2009 Dec; 30(12):2123-9.
Score: 0.013
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Cellular uptake and cytotoxicity of gold nanorods: molecular origin of cytotoxicity and surface effects. Small. 2009 Mar; 5(6):701-8.
Score: 0.013
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DNA damage and homologous recombination signaling induced by thymidylate deprivation. Biochem Pharmacol. 2008 Oct 15; 76(8):987-96.
Score: 0.012
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Uracil in DNA: consequences for carcinogenesis and chemotherapy. Biochem Pharmacol. 2008 Sep 15; 76(6):697-706.
Score: 0.012
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Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase. DNA Repair (Amst). 2008 Feb 01; 7(2):162-9.
Score: 0.012
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Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. Chem Res Toxicol. 2006 Dec; 19(12):1580-94.
Score: 0.011
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Determination of apoptosis, uracil incorporation, DNA strand breaks, and sister chromatid exchanges under conditions of thymidylate deprivation in a model of BER deficiency. Biochem Pharmacol. 2005 Nov 15; 70(10):1458-68.
Score: 0.010
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Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small. 2005 Mar; 1(3):325-7.
Score: 0.010
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Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases. Chem Res Toxicol. 2005 Jan; 18(1):87-94.
Score: 0.009
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Inhibitors of the PLK1 polo-box domain: drug design strategies and therapeutic opportunities in cancer. Expert Opin Drug Discov. 2023 01; 18(1):65-81.
Score: 0.008
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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE. Eur J Med Chem. 2022 Jan 05; 227:113926.
Score: 0.008
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Improving oncology biosimilar launches in the EU, the USA, and Japan: an updated Policy Review from the Southern Network on Adverse Reactions. Lancet Oncol. 2020 12; 21(12):e575-e588.
Score: 0.007
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Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly. Biochem Pharmacol. 2020 12; 182:114280.
Score: 0.007
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Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor. ChemMedChem. 2020 06 17; 15(12):1058-1066.
Score: 0.007
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Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Sci Rep. 2017 02 22; 7:43023.
Score: 0.006
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Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016 Apr 01; 105:23-33.
Score: 0.005
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Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity. J Med Chem. 2015 Jan 08; 58(1):433-42.
Score: 0.005
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5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway. DNA Repair (Amst). 2014 Dec; 24:15-25.
Score: 0.005
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Regulatory and clinical considerations for biosimilar oncology drugs. Lancet Oncol. 2014 Dec; 15(13):e594-e605.
Score: 0.005
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Current assessment of polo-like kinases as anti-tumor drug targets. Expert Opin Drug Discov. 2014 Jul; 9(7):773-89.
Score: 0.005
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Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. Carcinogenesis. 2013 Feb; 34(2):277-86.
Score: 0.004
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Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity. Int J Cancer. 2012 Apr 01; 130(7):1660-70.
Score: 0.004
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One-pot synthesis of silica-coated magnetic plasmonic tracer nanoparticles. Chem Commun (Camb). 2008 Dec 14; (46):6140-2.
Score: 0.003
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Induction of intrachromosomal homologous recombination in human cells by raltitrexed, an inhibitor of thymidylate synthase. DNA Repair (Amst). 2008 Oct 01; 7(10):1624-35.
Score: 0.003
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Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase. J Biol Chem. 2004 Sep 10; 279(37):38177-83.
Score: 0.002