Campbell McInnes to Crystallography, X-Ray
This is a "connection" page, showing publications Campbell McInnes has written about Crystallography, X-Ray.
Connection Strength
0.431
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Structural and functional analysis of cyclin D1 reveals p27 and substrate inhibitor binding requirements. ACS Chem Biol. 2010 Dec 17; 5(12):1169-82.
Score: 0.089
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Catch the kinase conformer. Chem Biol. 2006 Jul; 13(7):693-4.
Score: 0.066
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Strategies for the design of potent and selective kinase inhibitors. Curr Pharm Des. 2005; 11(14):1845-63.
Score: 0.059
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Structural determinants of CDK4 inhibition and design of selective ATP competitive inhibitors. Chem Biol. 2004 Apr; 11(4):525-34.
Score: 0.056
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Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors. J Med Chem. 2010 Mar 11; 53(5):2136-45.
Score: 0.021
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Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design. ChemMedChem. 2009 Jul; 4(7):1120-8.
Score: 0.020
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REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors. Chembiochem. 2006 Dec; 7(12):1909-15.
Score: 0.017
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Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb; 13(2):201-11.
Score: 0.016
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Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding. J Mol Biol. 2005 Jul 15; 350(3):587-98.
Score: 0.015
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Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):1871-6.
Score: 0.015
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Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes. Org Biomol Chem. 2004 Oct 07; 2(19):2735-41.
Score: 0.015
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2-Anilino-4-(thiazol-5-yl)pyrimidine CDK inhibitors: synthesis, SAR analysis, X-ray crystallography, and biological activity. J Med Chem. 2004 Mar 25; 47(7):1662-75.
Score: 0.014
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Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange. Structure. 2003 Dec; 11(12):1537-46.
Score: 0.014
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Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop. Structure. 2003 Apr; 11(4):399-410.
Score: 0.013