Mitzi Nagarkatti to Mice
This is a "connection" page, showing publications Mitzi Nagarkatti has written about Mice.
Connection Strength
4.587
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AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver. Front Immunol. 2022; 13:899609.
Score: 0.086
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Effects of Acute 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exposure on the Circulating and Cecal Metabolome Profile. Int J Mol Sci. 2021 Oct 30; 22(21).
Score: 0.082
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Protective effects of ?9 -tetrahydrocannabinol against enterotoxin-induced acute respiratory distress syndrome are mediated by modulation of microbiota. Br J Pharmacol. 2020 11; 177(22):5078-5095.
Score: 0.076
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?9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression. Int J Mol Sci. 2020 Aug 28; 21(17).
Score: 0.076
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Cannabidiol Regulates Gene Expression in Encephalitogenic T cells Using Histone Methylation and noncoding RNA during Experimental Autoimmune Encephalomyelitis. Sci Rep. 2019 10 31; 9(1):15780.
Score: 0.072
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Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. Brain Behav Immun. 2019 11; 82:25-35.
Score: 0.070
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Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells. Front Immunol. 2019; 10:1049.
Score: 0.069
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The role of gut microbiota in shaping the relapse-remitting and chronic-progressive forms of multiple sclerosis in mouse models. Sci Rep. 2019 05 06; 9(1):6923.
Score: 0.069
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Computational prediction and in vitro validation of VEGFR1 as a novel protein target for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Sci Rep. 2019 05 02; 9(1):6810.
Score: 0.069
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MicroRNA-92 Expression in CD133+ Melanoma Stem Cells Regulates Immunosuppression in the Tumor Microenvironment via Integrin-Dependent Activation of TGF?. Cancer Res. 2019 07 15; 79(14):3622-3635.
Score: 0.069
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Resveratrol (3, 5, 4'-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain. J Neuroimmune Pharmacol. 2019 09; 14(3):462-477.
Score: 0.069
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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study. BMC Struct Biol. 2018 12 06; 18(1):15.
Score: 0.067
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Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation. Toxicology. 2018 12 01; 410:49-58.
Score: 0.066
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MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages. Int J Obes (Lond). 2018 06; 42(6):1140-1150.
Score: 0.065
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CD44 deletion leading to attenuation of experimental autoimmune encephalomyelitis results from alterations in gut microbiome in mice. Eur J Immunol. 2017 07; 47(7):1188-1199.
Score: 0.061
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RNA-seq Analysis of d9-Tetrahydrocannabinol-treated T Cells Reveals Altered Gene Expression Profiles That Regulate Immune Response and Cell Proliferation. J Biol Chem. 2016 07 22; 291(30):15460-72.
Score: 0.057
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Production of endocannabinoids by activated T?cells and B?cells modulates inflammation associated with delayed-type hypersensitivity. Eur J Immunol. 2016 06; 46(6):1472-9.
Score: 0.057
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Marijuana-derived ?-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation. J Mol Med (Berl). 2016 09; 94(9):1039-51.
Score: 0.056
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Dietary Indoles Suppress Delayed-Type Hypersensitivity by Inducing a Switch from Proinflammatory Th17 Cells to Anti-Inflammatory Regulatory T Cells through Regulation of MicroRNA. J Immunol. 2016 Feb 01; 196(3):1108-22.
Score: 0.055
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Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor ? in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. J Immunol. 2015 Jun 01; 194(11):5211-22.
Score: 0.052
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Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages. Mol Nutr Food Res. 2015 May; 59(5):853-64.
Score: 0.052
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Exposure to diethylstilbestrol during pregnancy modulates microRNA expression profile in mothers and fetuses reflecting oncogenic and immunological changes. Mol Pharmacol. 2015 May; 87(5):842-54.
Score: 0.052
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?9-Tetrahydrocannabinol-mediated epigenetic modifications elicit myeloid-derived suppressor cell activation via STAT3/S100A8. J Leukoc Biol. 2015 Apr; 97(4):677-88.
Score: 0.052
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Role of miRNA in the regulation of inflammatory genes in staphylococcal enterotoxin B-induced acute inflammatory lung injury and mortality. Toxicol Sci. 2015 Apr; 144(2):284-97.
Score: 0.051
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Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease. Int Rev Immunol. 2015; 34(5):403-14.
Score: 0.049
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Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses. J Biol Chem. 2014 Jul 04; 289(27):18707-18.
Score: 0.049
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Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice. J Pharmacol Exp Ther. 2014 Jul; 350(1):99-109.
Score: 0.049
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Staphylococcal enterotoxin B-induced microRNA-155 targets SOCS1 to promote acute inflammatory lung injury. Infect Immun. 2014 Jul; 82(7):2971-9.
Score: 0.049
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Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. PLoS One. 2014; 9(4):e93954.
Score: 0.049
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Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1. J Leukoc Biol. 2014 Apr; 95(4):609-19.
Score: 0.048
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Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by ?9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein a by microRNA-690. J Biol Chem. 2013 Dec 27; 288(52):36810-26.
Score: 0.047
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Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells. Br J Pharmacol. 2013 Jul; 169(6):1305-21.
Score: 0.046
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MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis. Eur J Immunol. 2013 Jan; 43(1):104-14.
Score: 0.044
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Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury. Br J Pharmacol. 2012 Nov; 167(6):1244-58.
Score: 0.044
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Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expression. PLoS One. 2012; 7(9):e45054.
Score: 0.044
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs. J Pharmacol Exp Ther. 2012 Nov; 343(2):351-61.
Score: 0.043
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Acute lung injury induced by Staphylococcal enterotoxin B: disruption of terminal vessels as a mechanism of induction of vascular leak. Microsc Microanal. 2012 Jun; 18(3):445-452.
Score: 0.043
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Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma. PLoS One. 2012; 7(4):e35650.
Score: 0.043
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CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury. Infect Immun. 2011 Aug; 79(8):3141-8.
Score: 0.040
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CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis. J Immunol. 2011 Jun 15; 186(12):6955-64.
Score: 0.040
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Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol. PLoS One. 2011 Apr 01; 6(4):e18281.
Score: 0.040
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Bryostatin-1, a naturally occurring antineoplastic agent, acts as a Toll-like receptor 4 (TLR-4) ligand and induces unique cytokines and chemokines in dendritic cells. J Biol Chem. 2011 Jan 07; 286(1):24-34.
Score: 0.038
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Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis. J Neuroimmunol. 2010 Jun; 223(1-2):55-64.
Score: 0.037
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Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin. J Immunol. 2009 Jul 01; 183(1):172-80.
Score: 0.035
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CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation. J Leukoc Biol. 2008 Jul; 84(1):134-42.
Score: 0.032
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Blockade of hyaluronan inhibits IL-2-induced vascular leak syndrome and maintains effectiveness of IL-2 treatment for metastatic melanoma. J Immunol. 2007 Sep 15; 179(6):3715-23.
Score: 0.031
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Role of CD4(+)CD25(+) T regulatory cells in IL-2-induced vascular leak. Int Immunol. 2006 Oct; 18(10):1461-71.
Score: 0.029
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Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression. Mol Pharmacol. 2006 Sep; 70(3):897-908.
Score: 0.028
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Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage. Infect Immun. 2005 Jan; 73(1):50-61.
Score: 0.026
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Bryostatin-1 enhances the maturation and antigen-presenting ability of murine and human dendritic cells. Cancer Res. 2004 Sep 15; 64(18):6756-65.
Score: 0.025
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Role of CD44 and hyaluronic acid (HA) in activation of alloreactive and antigen-specific T cells by bone marrow-derived dendritic cells. J Immunother. 2004 Jan-Feb; 27(1):1-12.
Score: 0.024
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Combined deficiency in CD44 and Fas leads to exacerbation of lymphoproliferative and autoimmune disease. Int Immunol. 2003 Nov; 15(11):1327-40.
Score: 0.024
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Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver. Clin Immunol. 2003 Nov; 109(2):144-53.
Score: 0.024
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Targeted deletion of CD44v7 exon leads to decreased endothelial cell injury but not tumor cell killing mediated by interleukin-2-activated cytolytic lymphocytes. J Biol Chem. 2003 Oct 31; 278(44):43818-30.
Score: 0.023
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Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice. Sci Rep. 2022 10 05; 12(1):16668.
Score: 0.022
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Production of MHCII-expressing classical monocytes increases during aging in mice and humans. Aging Cell. 2022 Oct; 21(10):e13701.
Score: 0.022
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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood. 2002 Jul 15; 100(2):627-34.
Score: 0.022
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Identification and Biosynthesis of Pro-Inflammatory Sulfonolipids from an Opportunistic Pathogen Chryseobacterium gleum. ACS Chem Biol. 2022 05 20; 17(5):1197-1206.
Score: 0.021
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The Ability of Resveratrol to Attenuate Ovalbumin-Mediated Allergic Asthma Is Associated With Changes in Microbiota Involving the Gut-Lung Axis, Enhanced Barrier Function and Decreased Inflammation in the Lungs. Front Immunol. 2022; 13:805770.
Score: 0.021
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Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel. Nat Commun. 2022 01 26; 13(1):525.
Score: 0.021
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Emodin reduces tumor burden by diminishing M2-like macrophages in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2022 03 01; 322(3):G383-G395.
Score: 0.021
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Biodegradable polycaprolactone metallopolymer-antibiotic bioconjugates containing phenylboronic acid and cobaltocenium for antimicrobial application. Biomater Sci. 2021 Oct 26; 9(21):7237-7246.
Score: 0.021
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Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. Toxicology. 2021 09; 461:152901.
Score: 0.020
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Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice. Int J Mol Sci. 2021 Jul 22; 22(15).
Score: 0.020
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The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota. Front Immunol. 2021; 12:684727.
Score: 0.020
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Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis. J Crohns Colitis. 2021 Jun 22; 15(6):1032-1048.
Score: 0.020
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CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death. J Immunol. 2001 May 15; 166(10):5889-97.
Score: 0.020
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Extracts of select endemic plants from the Republic of Mauritius exhibiting anti-cancer and immunomodulatory properties. Sci Rep. 2021 02 19; 11(1):4272.
Score: 0.020
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AhR Activation Leads to Alterations in the Gut Microbiome with Consequent Effect on Induction of Myeloid Derived Suppressor Cells in a CXCR2-Dependent Manner. Int J Mol Sci. 2020 Dec 17; 21(24).
Score: 0.019
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Autophagy Inhibition Enables Nrf2 to Exaggerate the Progression of Diabetic Cardiomyopathy in Mice. Diabetes. 2020 12; 69(12):2720-2734.
Score: 0.019
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Immune and microRNA responses to Helicobacter muridarum infection and indole-3-carbinol during colitis. World J Gastroenterol. 2020 Aug 28; 26(32):4763-4785.
Score: 0.019
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Higher intestinal and circulatory lactate associated NOX2 activation leads to an ectopic fibrotic pathology following microcystin co-exposure in murine fatty liver disease. Comp Biochem Physiol C Toxicol Pharmacol. 2020 Dec; 238:108854.
Score: 0.019
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Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance. Environ Toxicol Pharmacol. 2020 Nov; 80:103457.
Score: 0.019
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Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. J Neuroinflammation. 2020 Jul 04; 17(1):201.
Score: 0.019
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Apigenin Modulates Dendritic Cell Activities and Curbs Inflammation Via RelB Inhibition in the Context of Neuroinflammatory Diseases. J Neuroimmune Pharmacol. 2021 06; 16(2):403-424.
Score: 0.019
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Mature Vascular Smooth Muscle Cells, but Not Endothelial Cells, Serve as the Major Cellular Source of Intimal Hyperplasia in Vein Grafts. Arterioscler Thromb Vasc Biol. 2020 08; 40(8):1870-1890.
Score: 0.019
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Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner. JCI Insight. 2020 01 16; 5(1).
Score: 0.018
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Facial Amphiphilicity-Induced Polymer Nanostructures for Antimicrobial Applications. ACS Appl Mater Interfaces. 2020 May 13; 12(19):21221-21230.
Score: 0.018
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Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis. Environ Toxicol Pharmacol. 2020 Jan; 73:103281.
Score: 0.018
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Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity. Toxicol Appl Pharmacol. 1999 Oct 15; 160(2):141-55.
Score: 0.018
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AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes. J Immunol. 2019 10 01; 203(7):1830-1844.
Score: 0.018
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Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation. Toxicol Appl Pharmacol. 2019 10 15; 381:114714.
Score: 0.018
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Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G408-G428.
Score: 0.018
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Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice. Sci Rep. 2019 07 19; 9(1):10520.
Score: 0.018
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Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease. Sci Rep. 2019 06 19; 9(1):8742.
Score: 0.017
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Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity. J Biol Chem. 2019 05 10; 294(19):7669-7681.
Score: 0.017
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Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells. J Leukoc Biol. 2019 08; 106(2):467-480.
Score: 0.017
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Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota. Brain Behav Immun. 2019 08; 80:44-55.
Score: 0.017
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Resveratrol Attenuates Allergic Asthma and Associated Inflammation in the Lungs Through Regulation of miRNA-34a That Targets FoxP3 in Mice. Front Immunol. 2018; 9:2992.
Score: 0.017
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Role of spontaneous and interleukin-2-induced natural killer cell activity in the cytotoxicity and rejection of Fas+ and Fas- tumor cells. Blood. 1998 Dec 01; 92(11):4248-55.
Score: 0.017
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Effects of high fat diet-induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model. Cancer Biol Ther. 2019; 20(4):487-496.
Score: 0.017
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Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.
Score: 0.017
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Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Front Immunol. 2018; 9:1782.
Score: 0.016
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Genistein induces macrophage polarization and systemic cytokine to ameliorate experimental colitis. PLoS One. 2018; 13(7):e0199631.
Score: 0.016
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Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness. Toxicol Appl Pharmacol. 2018 07 01; 350:64-77.
Score: 0.016
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Characterization of phenotypic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocytes in vivo and its effect on apoptosis. Toxicol Appl Pharmacol. 1998 May; 150(1):117-24.
Score: 0.016
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An endogenous aryl hydrocarbon receptor ligand, ITE, induces regulatory T cells and ameliorates experimental colitis. Am J Physiol Gastrointest Liver Physiol. 2018 08 01; 315(2):G220-G230.
Score: 0.016
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High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. Redox Biol. 2018 07; 17:1-15.
Score: 0.016
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MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target. Eur J Immunol. 2018 06; 48(6):1059-1073.
Score: 0.016
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Resveratrol protects mice against SEB-induced acute lung injury and mortality by miR-193a modulation that targets TGF-? signalling. J Cell Mol Med. 2018 05; 22(5):2644-2655.
Score: 0.016
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Charged Metallopolymer-Grafted Silica Nanoparticles for Antimicrobial Applications. Biomacromolecules. 2018 02 12; 19(2):417-425.
Score: 0.016
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Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity. Sci Rep. 2017 11 15; 7(1):15645.
Score: 0.016
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Trio Act of Boronolectin with Antibiotic-Metal Complexed Macromolecules toward Broad-Spectrum Antimicrobial Efficacy. ACS Infect Dis. 2017 11 10; 3(11):845-853.
Score: 0.016
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Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma. Biochem Biophys Res Commun. 2017 11 04; 493(1):598-603.
Score: 0.015
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Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Sci Rep. 2017 06 02; 7(1):2707.
Score: 0.015
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Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation. PLoS One. 2017; 12(3):e0172914.
Score: 0.015
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Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo. Toxicol Appl Pharmacol. 1997 Feb; 142(2):367-77.
Score: 0.015
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Evidence for the participation of interleukin-2 (IL-2) and IL-4 in the regulation of autonomous growth and tumorigenesis of transformed cells of lymphoid origin. Blood. 1997 Jan 15; 89(2):610-20.
Score: 0.015
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Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model. Cancer Biol Ther. 2017 02; 18(2):85-93.
Score: 0.015
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Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds. Oncotarget. 2017 Jan 03; 8(1):228-237.
Score: 0.015
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A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. PLoS One. 2016; 11(12):e0167979.
Score: 0.015
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TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. Free Radic Biol Med. 2017 01; 102:260-273.
Score: 0.015
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Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G699-G712.
Score: 0.014
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Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties. Oncotarget. 2016 Aug 16; 7(33):52928-52939.
Score: 0.014
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Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation. Brain Behav Immun. 2017 Jan; 59:10-20.
Score: 0.014
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Effect of radon on the immune system: alterations in the cellularity and functions of T cells in lymphoid organs of mouse. J Toxicol Environ Health. 1996 Apr 19; 47(6):535-52.
Score: 0.014
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3,39-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B?Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells. J Pharmacol Exp Ther. 2016 Apr; 357(1):177-87.
Score: 0.014
-
High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G906-19.
Score: 0.014
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MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15; 310(6):G347-58.
Score: 0.014
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Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. Am J Physiol Gastrointest Liver Physiol. 2016 04 01; 310(7):G510-25.
Score: 0.014
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Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain. Int J Obes (Lond). 2016 05; 40(5):844-51.
Score: 0.014
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Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency. Hypertension. 2016 Jan; 67(1):107-17.
Score: 0.014
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A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):268-79.
Score: 0.014
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Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions. J Neuroimmune Pharmacol. 2016 Mar; 11(1):36-47.
Score: 0.013
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NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment. Am J Pathol. 2015 Jul; 185(7):1944-57.
Score: 0.013
-
Protective role of cannabinoid receptor 2 activation in galactosamine/lipopolysaccharide-induced acute liver failure through regulation of macrophage polarization and microRNAs. J Pharmacol Exp Ther. 2015 May; 353(2):369-79.
Score: 0.013
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Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis. PLoS One. 2015; 10(2):e0116780.
Score: 0.013
-
Kruppel-like factor KLF4 facilitates cutaneous wound healing by promoting fibrocyte generation from myeloid-derived suppressor cells. J Invest Dermatol. 2015 May; 135(5):1425-1434.
Score: 0.013
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Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan; 116(1):102-14.
Score: 0.013
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miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology. 2014 Nov; 143(3):478-89.
Score: 0.013
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Constitutive activation of the interleukin 2 gene in the induction of spontaneous in vitro transformation and tumorigenicity of T cells. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7638-42.
Score: 0.012
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3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways. J Pharmacol Exp Ther. 2014 Aug; 350(2):341-52.
Score: 0.012
-
Expression, regulation and function of microRNAs in multiple sclerosis. Int J Med Sci. 2014; 11(8):810-8.
Score: 0.012
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Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer. Cancer Biol Ther. 2014; 15(11):1456-67.
Score: 0.012
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Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene. J Exp Med. 1993 Dec 01; 178(6):2225-30.
Score: 0.012
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The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment. PLoS One. 2013; 8(11):e79751.
Score: 0.012
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Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression. Toxicol Appl Pharmacol. 2014 Jan 01; 274(1):7-16.
Score: 0.012
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Leptin antagonist ameliorates chronic colitis in IL-10?/? mice. Immunobiology. 2013 Dec; 218(12):1439-51.
Score: 0.011
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Role of interleukin-10 in the regulation of tumorigenicity of a T cell lymphoma. Leuk Lymphoma. 2013 Apr; 54(4):827-34.
Score: 0.011
-
The role of IL-2 in the activation and expansion of regulatory T-cells and the development of experimental autoimmune encephalomyelitis. Immunobiology. 2013 Apr; 218(4):674-82.
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Murine lymphocytes exhibit heterogeneity in their proliferative responsiveness to calcium ionophore. Cell Mol Biol (Noisy-le-grand). 1992 Aug-Sep; 38(5-6):533-43.
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A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis. J Biomed Biotechnol. 2012; 2012:785739.
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A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms. Cancer Prev Res (Phila). 2012 Apr; 5(4):685-96.
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Robust antimicrobial compounds and polymers derived from natural resin acids. Chem Commun (Camb). 2012 Jan 21; 48(6):916-8.
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Characterization of T lymphocyte clones isolated from BCNU-cured LSA mice. Int J Cell Cloning. 1991 Nov; 9(6):594-605.
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Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis. PLoS One. 2011; 6(8):e23522.
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Perinatal exposure to ?9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens. J Pharmacol Exp Ther. 2011 Nov; 339(2):607-17.
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Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice. Brain Behav Immun. 2012 Jan; 26(1):72-82.
Score: 0.010
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Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: evidence from an experimental murine model. J Pharmacol Exp Ther. 2011 Sep; 338(3):819-28.
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Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-?B. Mol Nutr Food Res. 2011 Aug; 55(8):1207-18.
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Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. Eur J Immunol. 2010 Dec; 40(12):3358-71.
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Immunomodulatory effects of nitrosoureas on the phenotype and functions of T cells in the thymus and periphery. Immunopharmacology. 1990 Nov-Dec; 20(3):153-64.
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Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis. Carcinogenesis. 2010 Oct; 31(10):1734-41.
Score: 0.009
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Resveratrol (3,5,4'-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Nutr Food Res. 2011 Feb; 55(2):209-19.
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Role of IL-2, IL-4 and IL-6 in the growth and differentiation of tumor-specific CD4+ T helper and CD8+ T cytotoxic cells. Int J Cancer. 1990 Jun 15; 45(6):1096-104.
Score: 0.009
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Characterization of tumor-infiltrating CD4+ T cells as Th1 cells based on lymphokine secretion and functional properties. J Immunol. 1990 Jun 15; 144(12):4898-905.
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An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes. J Ethnopharmacol. 2010 Jul 20; 130(2):222-30.
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Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prev Res (Phila). 2010 Apr; 3(4):549-59.
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American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells. Cancer Prev Res (Phila). 2010 Mar; 3(3):339-47.
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Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor. Cancer Res. 1989 Dec 01; 49(23):6587-92.
Score: 0.009
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Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis. J Pharmacol Exp Ther. 2010 Mar; 332(3):829-39.
Score: 0.009
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Aldicarb suppresses macrophage but not natural killer (NK) cell-mediated cytotoxicity of tumor cells. Bull Environ Contam Toxicol. 1989 Nov; 43(5):676-82.
Score: 0.009
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American ginseng preferentially suppresses STAT/iNOS signaling in activated macrophages. J Ethnopharmacol. 2009 Aug 17; 125(1):145-50.
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Calcium ionophores at concentrations mitogenic to normal murine T cells inhibit the proliferation of tumor cells in vitro. Cancer Commun. 1989; 1(5):329-34.
Score: 0.008
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American ginseng suppresses inflammation and DNA damage associated with mouse colitis. Carcinogenesis. 2008 Dec; 29(12):2351-9.
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Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells. Cell Immunol. 1988 Sep; 115(2):383-92.
Score: 0.008
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Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 2008 Sep; 29(9):1799-806.
Score: 0.008
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Score: 0.008
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Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells. Mol Pharmacol. 2008 Jun; 73(6):1722-35.
Score: 0.008
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Differential effects of BCNU on T cell, macrophage, natural killer and lymphokine-activated killer cell activities in mice bearing a syngeneic tumor. Cancer Immunol Immunother. 1988; 27(1):38-46.
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Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor. Mol Pharmacol. 2007 Dec; 72(6):1508-21.
Score: 0.008
-
CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: potential role for CB2-selective ligands as immunosuppressive agents. Clin Immunol. 2007 Mar; 122(3):259-70.
Score: 0.007
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Role of dioxin response element and nuclear factor-kappaB motifs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated regulation of Fas and Fas ligand expression. Mol Pharmacol. 2007 Jan; 71(1):145-57.
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Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol. Int J Toxicol. 2006 Jan-Feb; 25(1):9-15.
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Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery. Toxicol Appl Pharmacol. 2006 Apr 15; 212(2):119-26.
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The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor. J Immunol. 1985 Aug; 135(2):1510-7.
Score: 0.007
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Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells. J Immunol. 2005 Jul 01; 175(1):90-103.
Score: 0.007
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Aryl hydrocarbon receptor-dependent induction of loss of mitochondrial membrane potential in epididydimal spermatozoa by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Lett. 2005 Jun 17; 157(2):99-107.
Score: 0.007
-
Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J Immunol. 2005 Mar 15; 174(6):3281-9.
Score: 0.006
-
Mouse B cell activation is inhibited by CD44 cross-linking. Immunol Invest. 2005; 34(4):399-416.
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Score: 0.006
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Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. J Immunol. 2004 Aug 15; 173(4):2373-82.
Score: 0.006
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Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci. 2004 Mar; 78(1):96-106.
Score: 0.006
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Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity. Toxicol Sci. 2004 Mar; 78(1):116-24.
Score: 0.006
-
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on maternal immune response during pregnancy. Arch Toxicol. 2004 May; 78(5):290-300.
Score: 0.006
-
Effect of experimental dengue virus infection on immune response of the host. I. Nature of changes in T suppressor cell activity regulating the B and T cell responses to heterologous antigens. J Gen Virol. 1983 Jul; 64 (Pt 7):1441-7.
Score: 0.006
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Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays. Toxicology. 2002 Sep 16; 178(3):241-60.
Score: 0.005
-
Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J Pharmacol Exp Ther. 2002 Aug; 302(2):451-65.
Score: 0.005
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Enhanced activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity in peripheral T cells. Toxicology. 2001 Aug 13; 165(1):51-63.
Score: 0.005
-
Evidence for estradiol-induced apoptosis and dysregulated T cell maturation in the thymus. Toxicology. 2001 May 28; 163(1):49-62.
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-
Growth of FasL-bearing tumor cells in syngeneic murine host induces apoptosis and toxicity in Fas(+) organs. Blood. 2000 Mar 15; 95(6):2111-7.
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-
Evidence for the involvement of CD44 in endothelial cell injury and induction of vascular leak syndrome by IL-2. J Immunol. 1999 Aug 01; 163(3):1619-27.
Score: 0.004
-
Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome. J Immunol. 1998 Sep 15; 161(6):3077-86.
Score: 0.004
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Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness. Toxicology. 1998 Aug 21; 129(2-3):211-26.
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-
Fas-Fas ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: a lethal two-way street. Blood. 1997 Sep 01; 90(5):1952-9.
Score: 0.004
-
Hyaluronate-CD44 interactions can induce murine B-cell activation. Blood. 1997 Apr 15; 89(8):2901-8.
Score: 0.004
-
Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells. Toxicology. 1996 Jun 17; 110(1-3):153-67.
Score: 0.004
-
Immunotoxicity of AZT: inhibitory effect on thymocyte differentiation and peripheral T cell responsiveness to gp120 of human immunodeficiency virus. Toxicol Appl Pharmacol. 1995 Mar; 131(1):53-62.
Score: 0.003
-
Immunomodulatory properties of AZT. Ann N Y Acad Sci. 1993 Jun 23; 685:464-6.
Score: 0.003
-
CD4-CD8- thymocytes from MRL-lpr/lpr mice exhibit abnormal proportions of alpha beta- and gamma delta-TCR+ cells and demonstrate defective responsiveness when activated through the TCR. Cell Immunol. 1991 Oct 15; 137(2):269-82.
Score: 0.003
-
T-cell-receptor-independent activation of cytolytic activity of cytotoxic T lymphocytes mediated through CD44 and gp90MEL-14. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7877-81.
Score: 0.003
-
Immunosuppression by aldicarb of T cell responses to antigen-specific and polyclonal stimuli results from defective IL-1 production by the macrophages. Toxicol Appl Pharmacol. 1990 Dec; 106(3):408-17.
Score: 0.002
-
Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells. Clin Immunol Immunopathol. 1990 Oct; 57(1):148-62.
Score: 0.002
-
Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases. J Autoimmun. 1990 Jun; 3(3):271-88.
Score: 0.002
-
Evidence for the existence of distinct heterogeneity among the peripheral CD4-CD8- T cells from MRL-lpr/lpr mice based on the expression of the J11d marker, activation requirements, and functional properties. Cell Immunol. 1990 May; 127(2):442-57.
Score: 0.002
-
Macrophages but not B cells from aged mice are defective in stimulating autoreactive T cells in vitro. Mech Ageing Dev. 1990 Mar 15; 52(2-3):107-24.
Score: 0.002
-
Tumor-induced alteration in macrophage accessory cell activity on autoreactive T cells. Cancer Immunol Immunother. 1989; 30(3):170-6.
Score: 0.002
-
Impaired autoreactive T cell-induced T cell-T cell interaction in aged mice. Cell Immunol. 1988 Oct 15; 116(2):299-307.
Score: 0.002
-
Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice. J Immunol. 1988 Aug 15; 141(4):1120-5.
Score: 0.002
-
Characterization of an endogenous Lyt2+ T-suppressor-cell population regulating autoreactive T cells in vitro and in vivo. Cell Immunol. 1988 Mar; 112(1):64-77.
Score: 0.002
-
Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network. J Exp Med. 1985 Jul 01; 162(1):375-80.
Score: 0.002