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One or more keywords matched the following properties of Becker, Howard
PropertyValue
keywords alcohol dependence
overview Dr. Becker's overall research focus is directed at elucidating neurobiological mechanisms and environmental factors underlying the addictive effects of alcohol, including adaptive changes resulting from chronic alcohol exposure that play a role in promoting excessive alcohol consumption and enhanced relapse vulnerability. He leads a multidisciplinary research program involving use of animals models for studying factors (e.g., stress) that facilitate transition to uncontrolled drinking, with the goal of identifying and evaluating new therapeutic targets and strategies for treating problem drinking and alcoholism. His research is supported by numerous grants from NIH/NIAA and the VA, and he serves on several advisory and editorial boards. As Director of the Charleston Alcohol Research Center, he coordinates and actively promotes integration of preclinical and clinical investigations that focus on the general theme of treatment and treatment implications for alcohol use disorders. Additionally, he is actively engaged in mentoring graduate and postdoctoral students as well as junior faculty.
One or more keywords matched the following items that are connected to Becker, Howard
Item TypeName
Academic Article Consequences of multiple withdrawals from alcohol.
Academic Article Alcohol withdrawal and conditioning.
Academic Article Understanding how the brain perceives alcohol: neurobiological basis of ethanol discrimination.
Academic Article Development of ethanol withdrawal-related sensitization and relapse drinking in mice selected for high- or low-ethanol preference.
Academic Article Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption.
Academic Article Stereotypic wall climbing in mice during ethanol withdrawal: a new measure of physical dependence.
Academic Article Alcohol, pregnancy, and prostaglandins.
Academic Article Effect of pattern and number of chronic ethanol exposures on subsequent voluntary ethanol intake in C57BL/6J mice.
Academic Article Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes.
Academic Article The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008.
Academic Article Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?
Academic Article Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice.
Academic Article Effects of chronic intermittent ethanol exposure on orbitofrontal and medial prefrontal cortex-dependent behaviors in mice.
Concept Alcohol-Induced Disorders, Nervous System
Concept Alcoholism
Concept Alcohol-Related Disorders
Academic Article Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice.
Academic Article Alcohol dependence, withdrawal, and relapse.
Academic Article Operant ethanol self-administration in ethanol dependent mice.
Academic Article Animal models of excessive alcohol consumption: recent advances and future challenges.
Academic Article Neurochemical mechanisms of alcohol withdrawal.
Academic Article Aspirin pretreatment reduces ethanol withdrawal severity in a mouse model of binge drinking.
Academic Article Positive relationship between the number of prior ethanol withdrawal episodes and the severity of subsequent withdrawal seizures.
Academic Article Reduced sensitivity to the effects of clonidine on ethanol-stimulated locomotor activity in adult mouse offspring prenatally exposed to ethanol.
Academic Article Effects of prenatal ethanol exposure on later sensitivity to the low-dose stimulant actions of ethanol in mouse offspring: possible role of catecholamines.
Academic Article Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: an animal model of alcohol withdrawal "kindling".
Academic Article Teratogenic actions of ethanol in the mouse: a minireview.
Academic Article Kindling in alcohol withdrawal.
Academic Article Chronic intermittent ethanol exposure and withdrawal alters (3a,5a)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice.
Academic Article Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.
Academic Article KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.
Academic Article Forced swim stress increases ethanol consumption in C57BL/6J mice with a history of chronic intermittent ethanol exposure.
Academic Article Effect of different stressors on voluntary ethanol intake in ethanol-dependent and nondependent C57BL/6J mice.
Academic Article Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition.
Academic Article Brain pathways to recovery from alcohol dependence.
Academic Article Challenges and exciting new opportunities to advance personalized treatment for alcohol use disorder.
Academic Article The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.
Academic Article Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.
Academic Article An Animal Model of Alcohol Dependence to Screen Medications for Treating Alcoholism.
Academic Article Influence of stress associated with chronic alcohol exposure on drinking.
Academic Article Stress Facilitates the Development of Cognitive Dysfunction After Chronic Ethanol Exposure.
Academic Article Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol.
Academic Article Opposing actions of CRF-R1 and CB1 receptors on VTA-GABAergic plasticity following chronic exposure to ethanol.
Academic Article Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice.
Academic Article Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Academic Article Bioinformatics identification and pharmacological validation of Kcnn3/KCa2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice.
Academic Article The role of oxytocin in alcohol and drug abuse.
Academic Article The future of translational research on alcohol use disorder.
Academic Article Brain regional gene expression network analysis identifies unique interactions between chronic ethanol exposure and consumption.
Concept Fetal Alcohol Spectrum Disorders
Academic Article Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice.
Academic Article Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges.
Academic Article Alcohol Dependence Modifies Brain Networks Activated During Withdrawal and Reaccess: A c-Fos-Based Analysis in Mice.
Academic Article Oxytocin Reduces Sensitized Stress-Induced Alcohol Relapse in a Model of Posttraumatic Stress Disorder and Alcohol Use Disorder Comorbidity.
Academic Article TLR3 activation with poly I:C exacerbates escalated alcohol consumption in dependent male C57BL/6J mice.
Academic Article Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice.
Academic Article Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
Academic Article Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder.
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  • Alcoholism