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Chimowitz, Marc
One or more keywords matched the following properties of Chimowitz, Marc
PropertyValue
keywords Stroke research and clinical trials
keywords Outpatient stroke consultation
keywords Acute stroke management
overview Dr. Marc Chimowitz researches treatments to prevent stroke caused by narrowing of brain arteries. This field of research is especially relevant in South Carolina, which has the nation’s second-highest mortality rate from stroke. Stroke is the fourth leading cause of death in the United States. Stenosis, a blockage or narrowing of a brain artery caused by the build up of plaque, accounts for more than 50,000 of the 795,000 strokes that occur annually nationwide. Stenosis is particularly common in African Americans, Hispanics, Asian Americans, and people with diabetes. Dr. Chimowitz received funding from the National Institutes of Health for a $28.5 million, 50-center nationwide clinical trial, which he led from the Medical University of South Carolina. The study showed that aggressive medical management alone is superior to aggressive medical management combined with a specific type of brain stent for patients at high risk for stroke. Dr. Chomowitz and the team of investigators published the results from the Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial in The New England Journal of Medicine. This was one of the largest extramural research grants in South Carolina history. The trial studied the value of using stents to prevent strokes in patients whose brain arteries have hardened and narrowed due to plaque buildup (atherosclerotic stenosis). The findings of this study have the potential to revolutionize stroke care.
One or more keywords matched the following items that are connected to Chimowitz, Marc
Item TypeName
Academic Article Asymptomatic coronary artery disease in patients with stroke. Prevalence, prognosis, diagnosis, and treatment.
Academic Article Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: a scientific statement for healthcare professionals from the Stroke Council and the Council on Clinical Cardiology of the American Heart Association/American Stroke Association.
Academic Article Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.
Academic Article Best treatment for intracranial arterial stenosis? 50 years of uncertainty. The WASID Investigators.
Academic Article Mechanism of stroke in patients taking aspirin.
Academic Article The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) trial.
Academic Article Gender differences in outcomes among patients with symptomatic intracranial arterial stenosis.
Academic Article Leukocyte count and vascular risk in symptomatic intracranial atherosclerosis.
Academic Article Risk factor status and vascular events in patients with symptomatic intracranial stenosis.
Academic Article The NIH registry on use of the Wingspan stent for symptomatic 70-99% intracranial arterial stenosis.
Academic Article Prevalence and prognosis of coexistent asymptomatic intracranial stenosis.
Academic Article Use of dose modification schedules is effective for blinding trials of warfarin: evidence from the WASID study.
Academic Article Ipsilateral leg weakness associated with carotid stenosis.
Academic Article 10 questions about intracranial atherosclerotic stenosis.
Academic Article Etiology of motor or sensory stroke: a prospective study of the predictive value of clinical and radiological features.
Academic Article Collaterals dramatically alter stroke risk in intracranial atherosclerosis.
Academic Article Design of the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis trial.
Academic Article Current status of the management of symptomatic intracranial atherosclerotic disease: the rationale for a randomized trial of medical therapy and intracranial stenting.
Academic Article REACH MUSC: A Telemedicine Facilitated Network for Stroke: Initial Operational Experience.
Academic Article Detailed analysis of periprocedural strokes in patients undergoing intracranial stenting in Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS).
Academic Article Rationale, design, and implementation of aggressive risk factor management in the Stenting and Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial.
Academic Article Response to critique of the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial by Abou-Chebl and Steinmetz.
Academic Article Mechanisms of stroke after intracranial angioplasty and stenting in the SAMMPRIS trial.
Academic Article Periventricular lesions on MRI. Facts and theories.
Academic Article MUSC's comprehensive stroke program: changing what's possible in stroke care across South Carolina.
Academic Article Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women.
Academic Article Antithrombotic therapy for atherosclerotic intracranial arterial stenosis.
Academic Article Stroke in patients with fusiform vertebrobasilar aneurysms.
Academic Article Is there a role for heparin in the management of complications of subarachnoid hemorrhage?
Academic Article Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: a scientific statement for healthcare professionals from the Stroke Council and the Council on Clinical Cardiology of the American Heart Association/American Stroke Association.
Academic Article Left atrial spontaneous echo contrast is highly associated with previous stroke in patients with atrial fibrillation or mitral stenosis.
Academic Article Frequency and severity of asymptomatic coronary disease in patients with different causes of stroke.
Academic Article Predictors of ischemic stroke in the territory of a symptomatic intracranial arterial stenosis.
Academic Article Relationship between blood pressure and stroke recurrence in patients with intracranial arterial stenosis.
Academic Article Echocardiography in patients with symptomatic intracranial stenosis.
Academic Article Systemic risk factors associated with progression of atherosclerosis from the coronary to the carotid arteries.
Academic Article Early stroke risk after transient ischemic attack among individuals with symptomatic intracranial artery stenosis.
Academic Article Racial differences in vascular risk factors and outcomes of patients with intracranial atherosclerotic arterial stenosis.
Academic Article Treatment of intracranial atherosclerotic stenosis.
Academic Article Failure of antithrombotic therapy and risk of stroke in patients with symptomatic intracranial stenosis.
Academic Article Risk factors associated with major cerebrovascular complications after intracranial stenting.
Academic Article Causes and severity of ischemic stroke in patients with symptomatic intracranial arterial stenosis.
Academic Article Treatment of atherosclerotic intracranial arterial stenosis.
Academic Article Risk factors associated with severity and location of intracranial arterial stenosis.
Academic Article E-pearl: brachial artery embolus mimicking acute stroke.
Academic Article Stenting versus aggressive medical therapy for intracranial arterial stenosis.
Academic Article CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective.
Academic Article Risk factors and outcome of patients with symptomatic intracranial stenosis presenting with lacunar stroke.
Academic Article Endovascular treatment for acute ischemic stroke--still unproven.
Academic Article Intracranial stenting: SAMMPRIS.
Academic Article The Feinberg Award Lecture 2013: treatment of intracranial atherosclerosis: learning from the past and planning for the future.
Academic Article Ischemic stroke and TIA: clinical clues to common causes.
Academic Article Cardiac prognosis of patients with carotid stenosis and no history of coronary artery disease. Veterans Affairs Cooperative Study Group 167.
Concept Stroke
Concept National Institute of Neurological Disorders and Stroke (U.S.)
Academic Article Utilization of CT perfusion patient selection for mechanical thrombectomy irrespective of time: a comparison of functional outcomes and complications.
Academic Article Impact of operator and site experience on outcomes after angioplasty and stenting in the SAMMPRIS trial.
Academic Article The challenge of stroke prevention with intracranial arterial stenosis.
Academic Article In reply: Is there a contribution of anesthesia to the outcome of the SAMMPRIS trial?
Academic Article Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Academic Article Intracranial stenosis: impact of randomized trials on treatment preferences of US neurologists and neurointerventionists.
Academic Article Game changer for endovascular treatment of acute ischemic stroke?
Academic Article Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.
Academic Article Infarct patterns, collaterals and likely causative mechanisms of stroke in symptomatic intracranial atherosclerosis.
Academic Article Racial/Ethnic differences in poststroke rehabilitation outcomes.
Academic Article Characterization of intracranial atherosclerotic stenosis using high-resolution MRI study--rationale and design.
Academic Article Enrollment volume effect on risk factor control and outcomes in the SAMMPRIS trial.
Academic Article Noninvasive fractional flow on MRA predicts stroke risk of intracranial stenosis.
Academic Article Outcome in patients previously on antithrombotic therapy in the SAMMPRIS trial: subgroup analysis.
Academic Article Endovascular therapy for atherosclerotic intracranial arterial stenosis: back to the drawing board.
Academic Article Yet again no benefit of stenting over medical therapy.
Academic Article Do Patient Characteristics Explain the Differences in Outcome Between Medically Treated Patients in SAMMPRIS and WASID?
Academic Article Does the Stenting Versus Aggressive Medical Therapy Trial Support Stenting for Subgroups With Intracranial Stenosis?
Academic Article Contralateral reperfusion injury after carotid endarterectomy.
Academic Article Evaluation of coexistent carotid and coronary disease by combined angiography.
Academic Article Frequency, Risk Factors, and Outcome of Coexistent Small Vessel Disease and Intracranial Arterial Stenosis: Results From the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) Trial.
Academic Article Factors Associated With Recurrent Ischemic Stroke in the Medical Group of the SAMMPRIS Trial.
Academic Article Impact of the New American Heart Association/American Stroke Association Definition of Stroke on the Results of the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial.
Academic Article Angioplasty and Stenting.
Academic Article Postprandial Clearance of Oxidized Low-Density Lipoprotein in Patients with Stroke Due to Atherosclerosis.
Academic Article Stroke Caused by Atherosclerosis of the Major Intracranial Arteries.
Academic Article Nonprocedural Symptomatic Infarction and In-Stent Restenosis After Intracranial Angioplasty and Stenting in the SAMMPRIS Trial (Stenting and Aggressive Medical Management for the Prevention of Recurrent Stroke in Intracranial Stenosis).
Academic Article Carotid revascularization and medical management for asymptomatic carotid stenosis: Protocol of the CREST-2 clinical trials.
Academic Article Angioplasty, Stenting and Other Potential Treatments of Atherosclerotic Stenosis of the Intracranial Arteries: Past, Present and Future.
Academic Article Comparison of multistate Markov modeling with contemporary outcomes in a reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial.
Academic Article Relationship between Risk Factor Control and Compliance with a Lifestyle Modification Program in the Stenting Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis Trial.
Academic Article Treatment effect on ordinal functional outcome using piecewise multistate Markov model with unobservable baseline: an application to the modified Rankin scale.
Academic Article Rationale for ischemic conditioning to prevent stroke in patients with intracranial arterial stenosis.
Academic Article Hemodynamic Markers in the Anterior Circulation as Predictors of Recurrent Stroke in Patients With Intracranial Stenosis.
Academic Article Type and Duration of Exercise in the SAMMPRIS Trial.
Academic Article Impact of Baseline Features and Risk Factor Control on Cognitive Function in the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial.
Academic Article Infarct Recurrence in Intracranial Atherosclerosis: Results from the MyRIAD Study.
Academic Article National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond.
Academic Article Rationale, Design, and Implementation of Intensive Risk Factor Treatment in the CREST2 Trial.
Academic Article Dual Antiplatelet Therapy Beyond 90 days in Symptomatic Intracranial Stenosis in the SAMMPRIS Trial.
Academic Article Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial.
Academic Article Silent Myocardial Infarction and Stroke Risk: We Should Be Listening.
Academic Article Relationship Between Vascular Risk Factors and Location of Intracranial Atherosclerosis in the SAMMPRIS Trial.
Academic Article Mechanisms of early Recurrence in Intracranial Atherosclerotic Disease (MyRIAD): Rationale and design.
Concept Stroke, Lacunar
Concept Stroke Rehabilitation
Academic Article Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee.
Academic Article Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment.
Academic Article Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham-controlled trial in China.
Search Criteria
  • Stroke