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One or more keywords matched the following properties of Schacht, Joseph
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overview Dr. Schacht’s training and research experience encompass both basic and clinical neuroscience, and he has pushed to build a program of research that translates from basic neurobiological processes to behavioral and treatment outcomes. He has previously been funded by individual (F31) and institutional (T32) training fellowships from the National Institute on Drug Abuse (NIDA) and the National on Alcohol Abuse and Alcoholism (NIAAA). His current work, funded by an NIAAA K99/R00 Pathway to Independence award, focuses on the neurobiological substrates of the transition from heavy drinking to alcohol dependence. He is particularly known for his work in using behavioral genetics and functional neuroimaging to understand alcohol and drug craving and cue reactivity.
One or more keywords matched the following items that are connected to Schacht, Joseph
Item TypeName
Academic Article Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach.
Academic Article Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta-analysis and systematic review.
Academic Article Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues.
Academic Article Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.
Academic Article Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics.
Concept Alcoholism
Concept Alcohol-Related Disorders
Academic Article Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals.
Academic Article Pharmacologic treatment of alcoholism.
Academic Article Alcohol-Induced Stimulation Mediates the Effect of a GABRA2 SNP on Alcohol Self-Administrated among Alcohol-Dependent Individuals.
Academic Article The Reasons for Heavy Drinking Questionnaire: Factor Structure and Validity in Alcohol-Dependent Adults Involved in Clinical Trials.
Academic Article Associations Between Recent Heavy Drinking and Dorsal Anterior Cingulate N-Acetylaspartate and Glutamate Concentrations in Non-Treatment-Seeking Individuals with Alcohol Dependence.
Academic Article Neural substrates of cue reactivity: association with treatment outcomes and relapse.
Academic Article Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status.
Academic Article Aripiprazole Suppression of Drinking in a Clinical Laboratory Paradigm: Influence of Impulsivity and Self-Control.
Academic Article Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial.
Academic Article Nicotine-Use/Smoking Is Associated with the Efficacy of Naltrexone in the Treatment of Alcohol Dependence.
Academic Article The dopamine transporter VNTR polymorphism moderates the relationship between acute response to alcohol and future alcohol use disorder symptoms.
Academic Article Brain Glutamate, GABA, and Glutamine Levels and Associations with Recent Drinking in Treatment-Na?ve Individuals with Alcohol Use Disorder Versus Light Drinkers.
Academic Article Evidence for a unique association between fronto-cortical glycine levels and recent heavy drinking in treatment na?ve individuals with alcohol use disorder.
Academic Article Intraindividual changes in brain GABA, glutamate, and glutamine during monitored abstinence from alcohol in treatment-naive individuals with alcohol use disorder.
Academic Article Systematic review and meta-analysis of the moderating effect of rs1799971 in OPRM1, the mu-opioid receptor gene, on response to naltrexone treatment of alcohol use disorder.
Academic Article Clinical and Neural Correlates of Reward and Relief Drinking.
Academic Article Opioid and Dopamine Genes Interact to Predict Naltrexone Response in a Randomized Alcohol Use Disorder Clinical Trial.
Academic Article Epigenetic moderators of naltrexone efficacy in reducing heavy drinking in Alcohol Use Disorder: a randomized trial.
Academic Article Effects of pharmacological and genetic regulation of COMT activity in alcohol use disorder: a randomized, placebo-controlled trial of tolcapone.
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  • Alcoholism