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Ergul, Adviye
One or more keywords matched the following properties of Ergul, Adviye
PropertyValue
keywords stroke
overview My research program lies at the intersection of vascular biology, endocrinology and neuroscience. My laboratory, my training and expertise are focused on understanding the regulation of vascular function and structure in diabetes and hypertension in order to develop innovative strategies and therapeutics for the prevention and treatment of associated complications including ischemic stroke and cognitive impairment. These comorbidities not only increase the risk but also worsen the recovery and/or progression of cognitive impairment and stroke. All neuroprotective approaches have failed to produce any new therapies for these diseases. As a vascular biologist, I concentrated my efforts on the role of vasculoprotection and vascular restoration on brain repair. I use my uniquely combined expertise in endocrinology, physiology, pharmacology and vascular biology to identify novel treatments for stroke and cognitive impairment in both sexes.
One or more keywords matched the following items that are connected to Ergul, Adviye
Item TypeName
Concept Stroke
Academic Article Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke.
Academic Article Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature.
Academic Article Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke.
Academic Article The effect of endothelin receptor A antagonism on basilar artery endothelium-dependent relaxation after ischemic stroke.
Academic Article Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke.
Academic Article Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes.
Academic Article Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke.
Academic Article Reply to "Letter to the editor: 'Targeting cerebrovascular myogenic dysfunction in stroke'".
Academic Article SOD1 overexpression prevents acute hyperglycemia-induced cerebral myogenic dysfunction: relevance to contralateral hemisphere and stroke outcomes.
Academic Article Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4.
Academic Article Angiotensin II type 2 receptor stimulation with compound 21 improves neurological function after stroke in female rats: a pilot study.
Academic Article Neurovascular injury in acute hyperglycemia and diabetes: A comparative analysis in experimental stroke.
Academic Article Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke.
Academic Article Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes.
Academic Article Vascularization pattern after ischemic stroke is different in control versus diabetic rats: relevance to stroke recovery.
Academic Article Comparative analysis of the neurovascular injury and functional outcomes in experimental stroke models in diabetic Goto-Kakizaki rats.
Academic Article Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodeling.
Academic Article Targets for vascular protection after acute ischemic stroke.
Academic Article Post-stroke neovascularization and functional outcomes differ in diabetes depending on severity of injury and sex: Potential link to hemorrhagic transformation.
Academic Article Diabetes Worsens Functional Outcomes in Young Female Rats: Comparison of Stroke Models, Tissue Plasminogen Activator Effects, and Sexes.
Academic Article Tactics for vascular protection after acute ischemic stroke.
Academic Article Mechanisms of acute neurovascular protection with AT1 blockade after stroke: Effect of prestroke hypertension.
Academic Article Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
Academic Article Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells.
Academic Article Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes.
Academic Article Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats.
Academic Article Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na+ /H+ exchanger-1 antagonism.
Academic Article Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.
Academic Article Inflammation within the neurovascular unit: Focus on microglia for stroke injury and recovery.
Academic Article Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study.
Academic Article RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial.
Academic Article Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.
Academic Article Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial.
Academic Article Erratum to: Artery reopening is required for the neurorestorative effects of angiotensin modulation after experimental stroke.
Academic Article Response to Letter Regarding Article, "Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke".
Academic Article Artery reopening is required for the neurorestorative effects of angiotensin modulation after experimental stroke.
Academic Article Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes.
Academic Article Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke.
Academic Article Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke.
Academic Article Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period.
Academic Article Comparative Analysis of Different Methods of Ischemia/Reperfusion in Hyperglycemic Stroke Outcomes: Interaction with tPA.
Academic Article Erratum to: Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.
Academic Article Remote ischemic postconditioning: harnessing endogenous protection in a murine model of vascular cognitive impairment.
Academic Article Role of matrix metalloproteinase activity in the neurovascular protective effects of Angiotensin antagonism.
Academic Article Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.
Academic Article Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B.
Academic Article Hyperglycemia, acute ischemic stroke, and thrombolytic therapy.
Academic Article Cerebral neovascularization in diabetes: implications for stroke recovery and beyond.
Academic Article Remote ischemic perconditioning is effective after embolic stroke in ovariectomized female mice.
Academic Article Candesartan reduces the hemorrhage associated with delayed tissue plasminogen activator treatment in rat embolic stroke.
Academic Article Recommendations for preclinical research in hemorrhagic transformation.
Academic Article Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Academic Article Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke.
Academic Article Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke.
Academic Article Diet-induced obesity causes cerebral vessel remodeling and increases the damage caused by ischemic stroke.
Academic Article Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential.
Academic Article Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study.
Academic Article Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke.
Academic Article Cerebrovascular complications of diabetes: focus on stroke.
Academic Article Angiogenesis: a harmonized target for recovery after stroke.
Academic Article Minocycline prevents IL-6 increase after acute ischemic stroke.
Academic Article Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type".
Academic Article Nox2-derived superoxide contributes to cerebral vascular dysfunction in diet-induced obesity.
Grant Progressive Post Stroke Cognitive Impairment:Mechanisms & Intervention
Grant Vascular Injury and Recovery in Diabetic Ischemic Stroke
Academic Article Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis.
Academic Article Diabetes-related sex differences in the brain endothelin system following ischemia in vivo and in human brain endothelial cells in vitro.
Academic Article Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke.
Academic Article Endothelin-1 (ET-1) promotes a proinflammatory microglia phenotype in diabetic conditions.
Academic Article Delayed Administration of Angiotensin Receptor (AT2R) Agonist C21 Improves Survival and Preserves Sensorimotor Outcomes in Female Diabetic Rats Post-Stroke through Modulation of Microglial Activation.
Academic Article Stroke promotes the development of brain atrophy and delayed cell death in hypertensive rats.
Academic Article Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke.
Academic Article Progress and challenges in preclinical stroke recovery research.
Academic Article Impact of diabetes and ischemic stroke on the cerebrovasculature: A female perspective.
Academic Article Contralesional angiotensin type 2 receptor activation contributes to recovery in experimental stroke.
Academic Article Vascular contributions to cognitive impairment/dementia in diabetes: role of endothelial cells and pericytes.
Academic Article Cerebral microvascular matrix metalloproteinase-3 (MMP3) contributes to vascular injury after stroke in female diabetic rats.
Academic Article Deferoxamine prevents poststroke memory impairment in female diabetic rats: potential links to hemorrhagic transformation and ferroptosis.
Academic Article Acute Ischemic Stroke by Middle Cerebral Artery Occlusion in Rat Models of Diabetes: Importance of Pre-op and Post-op Care, Severity of Hyperglycemia, and Sex.
Search Criteria
  • Stroke