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Academic Article Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma.
Academic Article A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.
Academic Article A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice.
Academic Article Complement inhibition alleviates paraquat-induced acute lung injury.
Academic Article CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants.
Academic Article A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer.
Academic Article Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.
Academic Article Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
Academic Article A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury.
Academic Article Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.
Academic Article A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor.
Academic Article Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts.
Concept Recombinant Fusion Proteins
Academic Article Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy.
Academic Article A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury.
Academic Article Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury.
Academic Article Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy.
Academic Article In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries.
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  • Recombinant Fusion Proteins