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One or more keywords matched the following properties of Becker, Howard
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keywords relapse drinking
overview Dr. Becker's overall research focus is directed at elucidating neurobiological mechanisms and environmental factors underlying the addictive effects of alcohol, including adaptive changes resulting from chronic alcohol exposure that play a role in promoting excessive alcohol consumption and enhanced relapse vulnerability. He leads a multidisciplinary research program involving use of animals models for studying factors (e.g., stress) that facilitate transition to uncontrolled drinking, with the goal of identifying and evaluating new therapeutic targets and strategies for treating problem drinking and alcoholism. His research is supported by numerous grants from NIH/NIAA and the VA, and he serves on several advisory and editorial boards. As Director of the Charleston Alcohol Research Center, he coordinates and actively promotes integration of preclinical and clinical investigations that focus on the general theme of treatment and treatment implications for alcohol use disorders. Additionally, he is actively engaged in mentoring graduate and postdoctoral students as well as junior faculty.
One or more keywords matched the following items that are connected to Becker, Howard
Item TypeName
Academic Article Alcohol withdrawal and conditioning.
Academic Article Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens.
Academic Article A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal.
Academic Article Intensity and duration of chronic ethanol exposure is critical for subsequent escalation of voluntary ethanol drinking in mice.
Academic Article Chronic social isolation and chronic variable stress during early development induce later elevated ethanol intake in adult C57BL/6J mice.
Academic Article Development of ethanol withdrawal-related sensitization and relapse drinking in mice selected for high- or low-ethanol preference.
Academic Article Effects of stress on alcohol drinking: a review of animal studies.
Academic Article Repeated cycles of chronic intermittent ethanol exposure leads to the development of tolerance to aversive effects of ethanol in C57BL/6J mice.
Academic Article Animal models of excessive alcohol consumption in rodents.
Academic Article Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption.
Academic Article Sensitivity to ethanol in female mice: effects of ovariectomy and strain.
Academic Article Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice.
Academic Article Effect of pattern and number of chronic ethanol exposures on subsequent voluntary ethanol intake in C57BL/6J mice.
Academic Article Voluntary ethanol drinking in mice and ethanol concentrations in the nucleus accumbens.
Academic Article Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats.
Academic Article Similar ethanol drinking in adolescent and adult C57BL/6J mice after chronic ethanol exposure and withdrawal.
Academic Article Pre-pregnancy alcohol experience attenuates typical decrease in gestational alcohol consumption in mice.
Concept Drinking
Concept Alcohol Drinking
Concept Drinking Behavior
Academic Article Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice.
Academic Article Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models.
Academic Article Alcohol dependence, withdrawal, and relapse.
Academic Article Operant ethanol self-administration in ethanol dependent mice.
Academic Article Animal models of excessive alcohol consumption: recent advances and future challenges.
Academic Article Aspirin pretreatment reduces ethanol withdrawal severity in a mouse model of binge drinking.
Academic Article Effect of prenatal ethanol exposure on response to abrupt reward reduction.
Academic Article Effects of prenatal ethanol exposure on later sensitivity to the low-dose stimulant actions of ethanol in mouse offspring: possible role of catecholamines.
Academic Article Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.
Academic Article Repeated episodes of chronic intermittent ethanol promote insensitivity to devaluation of the reinforcing effect of ethanol.
Academic Article Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.
Academic Article The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.
Academic Article Effect of different stressors on voluntary ethanol intake in ethanol-dependent and nondependent C57BL/6J mice.
Academic Article Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.
Academic Article Novel anticonvulsants for reducing alcohol consumption: A review of evidence from preclinical rodent drinking models.
Academic Article The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.
Academic Article Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.
Academic Article Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains.
Academic Article Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort.
Academic Article The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.
Academic Article Oxytocin Reduces Ethanol Self-Administration in Mice.
Academic Article Influence of stress associated with chronic alcohol exposure on drinking.
Academic Article Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol.
Academic Article Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.
Academic Article Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice.
Academic Article Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice.
Academic Article Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress.
Academic Article Oxytocin attenuates stress-induced reinstatement of alcohol seeking behavior in male and female mice.
Academic Article Dynamic c-Fos changes in mouse brain during acute and protracted withdrawal from chronic intermittent ethanol exposure and relapse drinking.
Academic Article Kappa opioid receptors in the bed nucleus of the stria terminalis regulate binge-like alcohol consumption in male and female mice.
Academic Article Effects of ceftriaxone on ethanol drinking and GLT-1 expression in ethanol dependence and relapse drinking.
Academic Article Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Academic Article Bioinformatics identification and pharmacological validation of Kcnn3/KCa2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice.
Academic Article The histone methyltransferase G9a mediates stress-regulated alcohol drinking.
Academic Article Transcriptome Analysis of Alcohol Drinking in Non-Dependent and Dependent Mice Following Repeated Cycles of Forced Swim Stress Exposure.
Concept Binge Drinking
Academic Article Activation of hypothalamic oxytocin neurons reduces binge-like alcohol drinking through signaling at central oxytocin receptors.
Academic Article Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice.
Academic Article Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges.
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  • Drinking