Item Type | Name |
Academic Article
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Effects of CFTR, interleukin-10, and Pseudomonas aeruginosa on gene expression profiles in a CF bronchial epithelial cell Line.
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Academic Article
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Chaperone gp96-independent inhibition of endotoxin response by chaperone-based peptide inhibitors.
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Academic Article
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a7 helix region of aI domain is crucial for integrin binding to endoplasmic reticulum chaperone gp96: a potential therapeutic target for cancer metastasis.
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Academic Article
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The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis.
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Academic Article
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Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.
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Academic Article
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Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway.
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Concept
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Cytokines
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Concept
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Tandem Mass Spectrometry
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Concept
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Immunotherapy
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Concept
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Epithelial Cells
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Concept
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Enzyme-Linked Immunosorbent Assay
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Concept
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Protein Binding
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Concept
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T-Lymphocytes, Cytotoxic
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Concept
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Disease Models, Animal
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Concept
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Intestinal Mucosa
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Concept
|
Apoptosis
|
Concept
|
Tumor Burden
|
Concept
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Interleukin-10
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Concept
|
Receptors, Interleukin-1
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Concept
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Anti-Bacterial Agents
|
Concept
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Osteoclasts
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Lung Neoplasms
|
Concept
|
Protein Folding
|
Concept
|
RNA, Small Interfering
|
Concept
|
Basophils
|
Concept
|
Transcription Factor CHOP
|
Concept
|
Antigens
|
Concept
|
Caspase 1
|
Concept
|
Receptors, LDL
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Receptors, Antigen, T-Cell
|
Concept
|
Immunity, Cellular
|
Concept
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Alkylating Agents
|
Concept
|
Flow Cytometry
|
Concept
|
Unfolded Protein Response
|
Concept
|
Neoplasm Metastasis
|
Concept
|
Inositol 1,4,5-Trisphosphate Receptors
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Concept
|
PTEN Phosphohydrolase
|
Concept
|
Oncogenes
|
Concept
|
Bone and Bones
|
Concept
|
Mice, Inbred BALB C
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Concept
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Fluorescent Antibody Technique
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Concept
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Microscopy, Electron, Transmission
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Concept
|
Disease Progression
|
Concept
|
CD8-Positive T-Lymphocytes
|
Concept
|
Skin Pigmentation
|
Concept
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HSP70 Heat-Shock Proteins
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Concept
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Electrophoresis, Gel, Two-Dimensional
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Concept
|
Toll-Like Receptors
|
Concept
|
Macrophages
|
Concept
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Diethylnitrosamine
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Concept
|
Biomarkers, Tumor
|
Concept
|
Melanosomes
|
Concept
|
Endoplasmic Reticulum
|
Concept
|
Animals
|
Concept
|
Interleukin-23
|
Concept
|
Disease Susceptibility
|
Concept
|
Homeostasis
|
Concept
|
Dendritic Cells
|
Concept
|
Mice, Knockout
|
Concept
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eIF-2 Kinase
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Concept
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Neoplasms, Experimental
|
Concept
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Calcium
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Concept
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Blotting, Western
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Concept
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Bronchi
|
Concept
|
T-Lymphocytes, Regulatory
|
Concept
|
Lipopolysaccharides
|
Concept
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Thrombin
|
Concept
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L-Selectin
|
Concept
|
T-Lymphocyte Subsets
|
Concept
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Hyaluronan Receptors
|
Concept
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Epitopes, T-Lymphocyte
|
Concept
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Low Density Lipoprotein Receptor-Related Protein-1
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Concept
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Dose-Response Relationship, Drug
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Concept
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Chromatography, Liquid
|
Concept
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Cystic Fibrosis Transmembrane Conductance Regulator
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Concept
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Lymphocytes, Tumor-Infiltrating
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Concept
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Phenylthiohydantoin
|
Concept
|
Immunoprecipitation
|
Concept
|
Chromatography, Gel
|
Concept
|
CD11c Antigen
|
Concept
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Mice
|
Concept
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Cell Differentiation
|
Concept
|
Inflammation Mediators
|
Concept
|
Toll-Like Receptor 9
|
Concept
|
Bone Marrow Cells
|
Concept
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Colitis
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Cecum
|
Concept
|
Melanoma
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
Plasma Cells
|
Concept
|
Mice, Inbred C57BL
|
Concept
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Cornified Envelope Proline-Rich Proteins
|
Concept
|
Melanoma, Experimental
|
Concept
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RNA, Neoplasm
|
Concept
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Liver Neoplasms
|
Concept
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Blood Platelets
|
Concept
|
Mice, Transgenic
|
Concept
|
T-Lymphocytes
|
Concept
|
Transforming Growth Factor beta1
|
Concept
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CD11a Antigen
|
Concept
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Signal Transduction
|
Concept
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Immunity, Humoral
|
Concept
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Endometrial Neoplasms
|
Concept
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Cell Proliferation
|
Concept
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Gastrointestinal Tract
|
Concept
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Multiple Myeloma
|
Concept
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Humans
|
Concept
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Autoimmune Diseases
|
Concept
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Jurkat Cells
|
Concept
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Melanins
|
Concept
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Cell Movement
|
Concept
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CD24 Antigen
|
Concept
|
Antigen Presentation
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Sepsis
|
Concept
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Immunoglobulin A
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Cross-Priming
|
Concept
|
Inflammation
|
Concept
|
Mice, Inbred NOD
|
Concept
|
Protein Multimerization
|
Concept
|
Interleukin-17
|
Concept
|
Cell Cycle
|
Concept
|
Lipopolysaccharide Receptors
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Models, Animal
|
Concept
|
Interleukin-1beta
|
Concept
|
Immune Evasion
|
Concept
|
Lymphocyte Activation
|
Concept
|
Platelet Aggregation Inhibitors
|
Concept
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Inhibitor of Apoptosis Proteins
|
Concept
|
Immunotherapy, Adoptive
|
Concept
|
Structural Homology, Protein
|
Concept
|
Pseudomonas aeruginosa
|
Concept
|
Carcinoma, Hepatocellular
|
Concept
|
Binding Sites
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Mice, SCID
|
Concept
|
Bromodeoxyuridine
|
Concept
|
CD4-Positive T-Lymphocytes
|
Concept
|
Wnt Proteins
|
Concept
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Benzamides
|
Concept
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Alternative Splicing
|
Concept
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Breast Neoplasms
|
Concept
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B-Lymphocytes
|
Concept
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Glycolysis
|
Concept
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Polymerase Chain Reaction
|
Concept
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DNA Repair
|
Concept
|
Colon
|
Concept
|
Gene Deletion
|
Concept
|
CD18 Antigens
|
Concept
|
Tissue Array Analysis
|
Concept
|
HCT116 Cells
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Immunohistochemistry
|
Concept
|
Colonic Neoplasms
|
Concept
|
Immune Tolerance
|
Concept
|
Respiratory Mucosa
|
Concept
|
Cell Line, Tumor
|
Concept
|
Immunoblotting
|
Concept
|
RNA-Binding Proteins
|
Academic Article
|
Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma.
|
Academic Article
|
Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis.
|
Academic Article
|
Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells.
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Academic Article
|
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
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Academic Article
|
Surface Expression of TGF? Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer.
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Academic Article
|
Targeting inflammasome/IL-1 pathways for cancer immunotherapy.
|
Academic Article
|
CD24 blunts oral squamous cancer development and dampens the functional expansion of myeloid-derived suppressor cells.
|
Academic Article
|
Mapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90.
|
Academic Article
|
Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c+ cells.
|
Academic Article
|
Platelets subvert T cell immunity against cancer via GARP-TGF? axis.
|
Academic Article
|
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
|
Academic Article
|
Modulation of Endoplasmic Reticulum Stress Controls CD4+ T-cell Activation and Antitumor Function.
|
Academic Article
|
GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon.
|
Academic Article
|
Cutting Edge: Targeting Thrombocytes to Rewire Anticancer Immunity in the Tumor Microenvironment and Potentiate Efficacy of PD-1 Blockade.
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Academic Article
|
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?.
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Academic Article
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Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma.
|
Academic Article
|
Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target.
|
Concept
|
Proteolysis
|
Concept
|
Endoplasmic Reticulum Stress
|
Concept
|
Wnt Signaling Pathway
|
Concept
|
Th17 Cells
|
Concept
|
Inflammasomes
|
Concept
|
Low Density Lipoprotein Receptor-Related Protein-6
|
Concept
|
Programmed Cell Death 1 Receptor
|
Concept
|
NLR Proteins
|
Concept
|
Carcinogenesis
|
Concept
|
NLR Family, Pyrin Domain-Containing 3 Protein
|
Concept
|
X-Box Binding Protein 1
|
Concept
|
HEK293 Cells
|
Academic Article
|
Commensal gut bacterium critically regulates alveolar bone homeostasis.
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Academic Article
|
Type 2 dendritic cells mediate control of cytotoxic T cell resistant tumors.
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Academic Article
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B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity.
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