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Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1.
Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src.
Regulation of Skp2 levels by the Pim-1 protein kinase.
Proto-Oncogene Proteins c-pim-1
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogene Proteins c-met
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins pp60(c-src)
The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling.
Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.
Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer.
The COX-2-PGE2 Pathway Promotes Tumor Evasion in Colorectal Adenomas.