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Academic Article
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Gene therapy in hypertension: adenovirus-mediated kallikrein gene delivery in hypertensive rats.
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Academic Article
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Experimental kallikrein gene therapy in hypertension, cardiovascular and renal diseases.
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Academic Article
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Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat.
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Academic Article
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Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats.
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Academic Article
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Adenovirus-mediated kallikrein gene delivery reverses salt-induced renal injury in Dahl salt-sensitive rats.
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Academic Article
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Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands.
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Academic Article
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In vivo catabolism of human kallikrein-binding protein and its complex with tissue kallikrein.
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Academic Article
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Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR.
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Academic Article
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Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats.
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Academic Article
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Central delivery of human tissue kallikrein gene reduces blood pressure in hypertensive rats.
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Academic Article
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Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats.
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Academic Article
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Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty.
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Academic Article
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Human tissue kallikrein attenuates hypertension and secretes into circulation and urine after intramuscular gene delivery in hypertensive rats.
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Academic Article
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Adenovirus-mediated kallikrein gene transfer inhibits neointima formation via increased production of nitric oxide in rat artery.
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Academic Article
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Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure.
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Academic Article
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Bradykinin B(1) receptor mediates inhibition of neointima formation in rat artery after balloon angioplasty.
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Academic Article
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A positively charged loop on the surface of kallistatin functions to enhance tissue kallikrein inhibition by acting as a secondary binding site for kallikrein.
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Academic Article
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Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling.
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Academic Article
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Kallikrein multigene families and the regulation of their expression.
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Academic Article
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Reversal of angiogenic growth factor upregulation by revascularization of lower limb ischemia.
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Academic Article
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Adenovirus-mediated gene transfer for cardiovascular and renal diseases.
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Academic Article
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Localization and expression of tissue kallikrein and kallistatin in human blood vessels.
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Academic Article
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Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats.
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Academic Article
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Kallikrein-binding protein is induced by growth hormone in the dwarf rat.
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Academic Article
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Molecular cloning and analysis of the rat kallikrein-binding protein gene.
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Academic Article
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Circulating tissue kallikrein levels correlate with severity of carotid atherosclerosis.
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Academic Article
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Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress.
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Academic Article
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Adenovirus-mediated kallikrein gene delivery attenuates hypertension and protects against renal injury in deoxycorticosterone-salt rats.
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Academic Article
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Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion.
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Academic Article
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Reactive-site specificity of human kallistatin toward tissue kallikrein probed by site-directed mutagenesis.
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Academic Article
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Experimental therapy with tissue kallikrein against cerebral ischemia.
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Academic Article
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Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis.
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Academic Article
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The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction.
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Academic Article
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Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.
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Academic Article
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Tissue kallikrein infusion prevents cardiomyocyte apoptosis, inflammation and ventricular remodeling after myocardial infarction.
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Academic Article
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Roles of the P1, P2, and P3 residues in determining inhibitory specificity of kallistatin toward human tissue kallikrein.
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Academic Article
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Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction.
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Academic Article
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Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury.
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Academic Article
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Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway.
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Academic Article
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A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness.
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Academic Article
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Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats.
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Academic Article
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Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation.
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Academic Article
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Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing.
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Academic Article
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Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway.
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Academic Article
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Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene.
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Academic Article
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Co-localization of a kallikrein-like serine protease (arginine esterase A) and atrial natriuretic peptide in rat atrium.
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Academic Article
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Characterization of genes encoding rat tonin and a kallikrein-like serine protease.
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Academic Article
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Restriction fragment length polymorphisms mapped in spontaneously hypertensive rats using kallikrein probes.
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Academic Article
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Renal kallikrein mRNA localization by in situ hybridization.
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Academic Article
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Tissue kallikrein is related to the severity of coronary artery disease.
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Academic Article
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Tissue kallikrein-modified mesenchymal stem cells provide enhanced protection against ischemic cardiac injury after myocardial infarction.
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Academic Article
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Kallikrein gene delivery attenuates cardiac remodeling and promotes neovascularization in spontaneously hypertensive rats.
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Academic Article
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A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats.
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Academic Article
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Immunocytochemical localization of a kallikrein-like serine protease (esterase A) in rat salivary glands.
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Academic Article
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Identification and characterization of a tissue kallikrein in rat skeletal muscles.
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Academic Article
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Identification of latent tissue kallikrein, prolactin and growth hormone secretion in GH3 pituitary cells using modified radioimmunoassays.
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Academic Article
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Comparison of the distribution of tissue kallikrein and esterase A, a kallikrein-like enzyme, in rat kidney using specific monoclonal antibodies.
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Academic Article
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Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats.
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Academic Article
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Muscle delivery of human kallikrein gene reduces blood pressure in hypertensive rats.
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Academic Article
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Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence.
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Academic Article
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Comparative studies on P2 specificity of wild-type rat tissue kallikrein, Y99H:W215G mutant and tonin.
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Academic Article
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Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats.
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Academic Article
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Specificity determinants of rat tissue kallikrein probed by site-directed mutagenesis.
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Academic Article
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Identification and characterization of two promoters of rat kallikrein-binding protein gene.
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Academic Article
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Systemic and portal vein delivery of human kallikrein gene reduces blood pressure in hypertensive rats.
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Academic Article
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Differential regulation of kallikrein, kininogen, and kallikrein-binding protein in arterial hypertensive rats.
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Academic Article
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Tissue kallikrein inhibitors in mammals.
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Academic Article
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Evolution of the kallikrein gene family.
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Academic Article
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High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats.
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Academic Article
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High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model.
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Academic Article
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Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic rats.
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Academic Article
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Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shock.
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Academic Article
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Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis.
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Academic Article
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Tissue-specific expression and promoter analyses of the human tissue kallikrein gene in transgenic mice.
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Academic Article
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Expression of human tissue kallikrein in rat salivary glands and its secretion into circulation following adenovirus-mediated gene transfer.
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Academic Article
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Kallikrein gene therapy: a new strategy for hypertensive diseases.
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Academic Article
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Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways.
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Academic Article
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Kallikrein-kinin in stroke, cardiovascular and renal disease.
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Academic Article
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Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats.
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Academic Article
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Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats.
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Academic Article
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Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis.
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Academic Article
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Purification and characterization of recombinant tissue kallikrein from Escherichia coli and yeast.
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Academic Article
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Reversal of renal fibrosis, inflammation, and glomerular hypertrophy by kallikrein gene delivery.
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Academic Article
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Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways.
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Academic Article
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Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion.
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Academic Article
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Kallikrein-modified mesenchymal stem cell implantation provides enhanced protection against acute ischemic kidney injury by inhibiting apoptosis and inflammation.
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Academic Article
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Tissue kallikrein and kinin infusion promotes neovascularization in limb ischemia.
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Academic Article
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Tissue kallikrein elicits cardioprotection by direct kinin b2 receptor activation independent of kinin formation.
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Academic Article
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Differential interactions of human kallikrein-binding protein and alpha 1-antitrypsin with human tissue kallikrein.
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Academic Article
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A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor.
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Academic Article
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Structural analysis of a rat renal kallikrein gene.
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Academic Article
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Human kallistatin, a new tissue kallikrein-binding protein: purification and characterization.
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Academic Article
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Tissue kallikrein promotes cardiac neovascularization by enhancing endothelial progenitor cell functional capacity.
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Academic Article
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Tissue kallikrein-modified human endothelial progenitor cell implantation improves cardiac function via enhanced activation of akt and increased angiogenesis.
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Academic Article
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Identification and expression of kallikrein gene family in rat submandibular and prostate glands using monoclonal antibodies as specific probes.
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Academic Article
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Molecular cloning and characterization of two rat renal kallikrein genes.
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Academic Article
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Circulating autoantibodies to mammalian tissue kallikreins.
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Academic Article
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Cellular localization of tissue kallikrein and kallistatin mRNAs in human kidney.
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Academic Article
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Human tissue kallikrein induces hypotension in transgenic mice.
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Academic Article
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Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats.
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Academic Article
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Biochemical characterization and substrate specificity of rat prostate kallikrein (S3): comparison with tissue kallikrein, tonin and T-kininogenase.
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Academic Article
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Molecular cloning, purification and in situ localization of human colon kallikrein.
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Academic Article
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Localization of kallikrein gene family proteases in rat tissues.
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Academic Article
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Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues.
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Academic Article
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Intramuscular delivery of rat kallikrein-binding protein gene reverses hypotension in transgenic mice expressing human tissue kallikrein.
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Academic Article
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Histopathology of lymphatic tissues in transgenic mice expressing human tissue kallikrein gene.
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Academic Article
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Expression and characterization of rat kallikrein-binding protein in Escherichia coli.
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Academic Article
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Functional analysis of human tissue kallikrein in transgenic mouse models.
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Academic Article
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Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease.
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Academic Article
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High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice.
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Academic Article
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Expression and cellular localization of tissue kallikrein-kinin system in human adrenal gland.
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Academic Article
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Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension.
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Academic Article
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Tissue kallikrein-binding protein reduces blood pressure in transgenic mice.
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Academic Article
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Expression and cellular localization of the kallikrein-kinin system in human ocular tissues.
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Academic Article
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DNA polymorphisms in the 5'-flanking region of the human tissue kallikrein gene.
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Academic Article
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Effects of diabetes and insulin on expression of kallikrein and renin genes in the kidney.
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Academic Article
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New experimental evidence for a role of tissue kallikrein in hypertension.
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Academic Article
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Kallikrein gene therapy in newborn and adult hypertensive rats.
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Concept
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Kallikrein-Kinin System
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Concept
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Tissue Kallikreins
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Academic Article
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Tissue kallikrein-kinin therapy in hypertension and organ damage.
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Academic Article
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Kallikrein-kinin in stem cell therapy.
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Academic Article
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Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin.
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