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One or more keywords matched the following items that are connected to Chou, C.
Item TypeName
Academic Article Functional studies of the Mycobacterium tuberculosis iron-dependent regulator.
Academic Article Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases.
Academic Article Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing.
Academic Article Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells.
Academic Article Inhibition of HDAC2 protects the retina from ischemic injury.
Academic Article A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.
Academic Article Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.
Academic Article Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis.
Academic Article Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.
Academic Article Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate.
Academic Article Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors.
Academic Article Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes.
Academic Article Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.
Academic Article A novel class of small molecule inhibitors of HDAC6.
Academic Article Vitamin K: a structural basis for the design of novel neuroprotective agents?
Concept Nylons
Concept src Homology Domains
Concept Leukemia, Erythroblastic, Acute
Concept Protein Binding
Concept Neutrophils
Concept Disease Models, Animal
Concept DNA-Binding Proteins
Concept RNA, Small Interfering
Concept Vitamin K
Concept Mycobacterium tuberculosis
Concept Alkylating Agents
Concept Costs and Cost Analysis
Concept Magnetic Resonance Spectroscopy
Concept HeLa Cells
Concept Drug Discovery
Concept Cell Division
Concept Drug Design
Concept Polymers
Concept Cats
Concept Histone Deacetylase 1
Concept Mice, Inbred BALB C
Concept Sodium-Calcium Exchanger
Concept Body Weight
Concept Disulfides
Concept Mice, Obese
Concept Hydrogel, Polyethylene Glycol Dimethacrylate
Concept Sensitivity and Specificity
Concept Antineoplastic Agents, Alkylating
Concept Isoquinolines
Concept Vitamin K 3
Concept Cell Adhesion
Concept Macrophages
Concept Administration, Oral
Concept Animals
Concept Neurodegenerative Diseases
Concept Genes
Concept Chronic Disease
Concept Adenosine Triphosphate
Concept Silver
Concept Mice, Knockout
Concept Hydroxamic Acids
Concept Antineoplastic Agents
Concept Natriuretic Peptide, Brain
Concept Recombinant Proteins
Concept Blotting, Western
Concept Pancreatic Neoplasms
Concept Fusion Proteins, bcr-abl
Concept Neuroprotective Agents
Concept YY1 Transcription Factor
Concept Rats, Inbred BN
Concept Anticonvulsants
Concept Acetyltransferases
Concept Tumor Cells, Cultured
Concept Aminobutyrates
Concept Biopsy
Concept Dose-Response Relationship, Drug
Concept Iron
Concept Caspase 3
Concept Iron-Binding Proteins
Concept Obesity
Concept Chromatin
Concept Mice
Concept Ocular Hypertension
Concept Cell Line, Transformed
Concept DNA Primers
Concept Valproic Acid
Concept Insulin Resistance
Concept Models, Biological
Concept Epilepsy
Concept Drug Evaluation, Preclinical
Concept Transcription, Genetic
Concept Pyrroles
Concept Naphthoquinones
Concept Histone Deacetylases
Concept Dimerization
Concept Repressor Proteins
Concept Tryptophan
Concept Nickel
Concept Mice, Inbred C57BL
Concept Lysine
Concept Cells, Cultured
Concept Huntington Disease
Concept Decision Support Techniques
Concept Vitamin K 2
Concept G2 Phase
Concept Nucleic Acid Conformation
Concept Xenograft Model Antitumor Assays
Concept RNA, Messenger
Concept Cell Proliferation
Concept Survival Rate
Concept Humans
Concept Heart
Concept Laminin
Concept DNA, Bacterial
Concept Drug Screening Assays, Antitumor
Concept Chlorambucil
Concept Protein Structure, Tertiary
Concept Cardiomegaly
Concept Lymphocytes
Concept Inflammation
Concept Giant Cells
Concept Crystallography, X-Ray
Concept Analysis of Variance
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Models, Animal
Concept HL-60 Cells
Concept Histone Deacetylase Inhibitors
Concept Bacterial Proteins
Concept Cell Culture Techniques
Concept Clinical Competence
Concept Electroretinography
Concept Swimming
Concept Protein Structure, Quaternary
Concept K562 Cells
Concept Friedreich Ataxia
Concept Cyclization
Concept Pimelic Acids
Concept Acetylation
Concept Binding Sites
Concept Molecular Conformation
Concept Mice, Nude
Concept Mutagenesis
Concept Ischemic Preconditioning
Concept Neoplasm Proteins
Concept Leukemia, Myeloid, Acute
Concept Spectrometry, Fluorescence
Concept Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Concept Rats
Concept Reperfusion Injury
Concept In Situ Hybridization
Concept Metals
Concept Ions
Concept Models, Molecular
Concept Benzamides
Concept Enzyme Inhibitors
Concept Cell Line
Concept Proto-Oncogene Proteins c-fos
Concept Breast Neoplasms
Concept Lymphatic Metastasis
Concept Dimethylallyltranstransferase
Concept Polymerase Chain Reaction
Concept Sulfides
Concept Nitric Oxide Donors
Concept Protein Conformation
Concept Histone Deacetylase 2
Concept U937 Cells
Concept MicroRNAs
Concept Alkylation
Concept Promoter Regions, Genetic
Concept Gene Silencing
Concept Base Sequence
Concept Zebrafish
Concept Anisotropy
Concept Immunohistochemistry
Concept Cell Line, Tumor
Concept Molecular Sequence Data
Academic Article Novel Vitamin K analogs suppress seizures in zebrafish and mouse models of epilepsy.
Academic Article Acetylation: a lysine modification with neuroprotective effects in ischemic retinal degeneration.
Academic Article Acetylation preserves retinal ganglion cell structure and function in a chronic model of ocular hypertension.
Academic Article Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity.
Academic Article Short laminin peptide for improved neural stem cell growth.
Academic Article Discovery of a Pair of Diastereomers as Potent HDACs Inhibitors: Determination of Absolute Configuration, Biological Activity Comparison and Computational Study.
Academic Article Histone deacetylase inhibitors with enhanced enzymatic inhibition effects and potent in vitro and in vivo antitumor activities.
Academic Article Design and synthesis of a tetrahydroisoquinoline-based hydroxamate derivative (ZYJ-34v), an oral active histone deacetylase inhibitor with potent antitumor activity.
Academic Article Development of N-Hydroxycinnamamide-Based Histone Deacetylase Inhibitors with Indole-Containing Cap Group.
Academic Article The learning curve for sentinel node biopsy in breast cancer: practical considerations.
Academic Article Evidence for a non-canonical role of HDAC5 in regulation of the cardiac Ncx1 and Bnp genes.
Academic Article HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.
Academic Article Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor.
Academic Article Silver-catalyzed direct thiolation of quinones by activation of aryl disulfides to synthesize quinonyl aryl thioethers.
Academic Article Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.
Academic Article Ischemic preconditioning, retinal neuroprotection and histone deacetylase activities.
Academic Article Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.
Concept Chemistry Techniques, Synthetic
Concept MCF-7 Cells
Concept Molecular Docking Simulation
Concept Neuroprotection
Concept Imatinib Mesylate
Concept Histone Deacetylase 6
Concept Homeobox Protein Nkx-2.5
Concept HEK293 Cells
Search Criteria
  • Homeobox
  • Protein
  • Nkx
  • 2
  • 5