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PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation.
Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion.
Identifying specific kinase substrates through engineered kinases and ATP analogs.
MEK partner 1 (MP1): regulation of oligomerization in MAP kinase signaling.
Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.
Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion.
Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs.
ERK activation and nuclear signaling induced by the loss of cell/matrix adhesion stimulates anchorage-independent growth of ovarian cancer cells.
Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors.
Discovery of 3-(2-aminoethyl)-5-(3-phenyl-propylidene)-thiazolidine-2,4-dione as a dual inhibitor of the Raf/MEK/ERK and the PI3K/Akt signaling pathways.
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 14
Mitogen-Activated Protein Kinase 8
Rapid Renal Regulation of Peroxisome Proliferator-activated Receptor ? Coactivator-1a by Extracellular Signal-Regulated Kinase 1/2 in Physiological and Pathological Conditions.
Mitogen Activated Protein Kinase 7