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Optimizing the ongoing search for new treatments for Parkinson disease: using futility designs.
Flexible analytical methods for adding a treatment arm mid-study to an ongoing clinical trial.
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.
The established status epilepticus trial 2013.
Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials.
Predictors of cognitive outcomes in early Parkinson disease patients: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience.
An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project.
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus.
Transcranial Direct Current Stimulation vs Sham Stimulation to Treat Aphasia After Stroke: A Randomized Clinical Trial.
Characterizing patient compliance over six months in remote digital trials of Parkinson's and Huntington disease.
Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis.
A pragmatic, adaptive clinical trial design for a rare disease: The FOcal Cerebral Arteriopathy Steroid (FOCAS) trial.
The Utility of Domain-Specific End Points in Acute Stroke Trials.
Framework for advancing rigorous research.