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Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Ga(i2) protein.
Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins.
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins.
Toll-Like Receptor 4
Toll-Like Receptor 2
Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis.
Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis.
Use novel natural compound Sparstolonin B to treat bacterial sepsis
Toll Like Receptors