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Flume, Patrick
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overview Dr. Patrick Flume joined the faculty of the Pulmonary and Critical Care Division at the Medical University of South Carolina in 1993. He is now a Professor of Medicine and Pediatrics, overseeing a rapidly growing Cystic Fibrosis Center. Though he continues to practice general pulmonary and critical care medicine, his primary interests are in CF and bronchiectasis, and chronic lung infections, including nontuberculous mycobacteria. The MUSC Cystic Fibrosis Center is the principal CF program in South Carolina. They provide state-of-the-art care to patients and families with CF; provide primary educator of clinicians and basic scientists in the field of CF; and perform basic and clinical research in the field of CF. Dr. Flume is the MUSC CF Center Director and has national recognition by the national and international CF community having served on the Cystic Fibrosis Foundation Center Committee, the Adult Care Consensus Committee, the Advisory Task Force on Adult Issues, the Professional Education Committee, and as co-chair for the Pulmonary Practice Guidelines Committee. Dr. Flume has an active clinical research program and heads the MUSC Research Nexus.
One or more keywords matched the following items that are connected to Flume, Patrick
Item TypeName
Academic Article A pilot study of the efficacy of constant-infusion ceftazidime in the treatment of endobronchial infections in adults with cystic fibrosis.
Academic Article Pulmonary complications after esophagectomy.
Academic Article Wegener's granulomatosis in patients with rheumatoid arthritis.
Academic Article Transition programs in cystic fibrosis centers: perceptions of team members.
Academic Article Linezolid pharmacokinetics in adult patients with cystic fibrosis.
Academic Article Complications of cystic fibrosis in adults.
Academic Article An unusual presentation of cystic fibrosis in an adult.
Academic Article Pneumothorax in cystic fibrosis.
Academic Article Massive hemoptysis in cystic fibrosis.
Academic Article Mutations in the beta-subunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome.
Academic Article Superior vena cava syndrome related to indwelling intravenous catheters in patients with cystic fibrosis.
Academic Article Psychological functioning of adults with cystic fibrosis.
Academic Article The delta F508 mutation in cystic fibrosis and impact on sinus development.
Academic Article Update in cystic fibrosis 2009.
Academic Article A "story" of a woman with cystic fibrosis.
Academic Article Ivacaftor in subjects with cystic fibrosis who are homozygous for the F508del-CFTR mutation.
Academic Article Pooled analysis of two large randomised phase III inhaled mannitol studies in cystic fibrosis.
Academic Article Timing of inhaled tobramycin affects assessment of intravenous tobramycin pharmacokinetic monitoring.
Academic Article Infectious complications of lung transplantation. Impact of cystic fibrosis.
Academic Article The MUSC lung transplantation program: the first year's experience.
Academic Article Nebulizer use and maintenance by cystic fibrosis patients: a survey study.
Academic Article Detection of an apparent homozygous 3120G>A cystic fibrosis mutation on a routine carrier screen.
Academic Article Making the diagnosis of cystic fibrosis.
Academic Article Pulmonary complications in adult patients with cystic fibrosis.
Academic Article Cost-effective airway cultures in the cystic fibrosis patient.
Academic Article Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis.
Academic Article Smoothing the transition from pediatric to adult care: lessons learned.
Academic Article Treatment of pulmonary exacerbations in adult cystic fibrosis patients: a review.
Academic Article Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial.
Academic Article Pharmacokinetics and safety of MP-376 (levofloxacin inhalation solution) in cystic fibrosis subjects.
Academic Article Levofloxacin inhalation solution (MP-376) in patients with cystic fibrosis with Pseudomonas aeruginosa.
Academic Article Prerenal azotemia from excessive sweating in an adult with a cystic fibrosis gene mutation.
Academic Article Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.
Academic Article Lung transplantation for mechanically ventilated patients.
Academic Article The Fowler breathholding study revisited: continuous rating of respiratory sensation.
Academic Article Relief of the 'air hunger' of breathholding. A role for pulmonary stretch receptors.
Concept Adult
Concept Young Adult
Academic Article European Cystic Fibrosis Society Standards of Care: Best Practice guidelines.
Academic Article Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): two randomised double-blind, placebo-controlled phase 3 trials.
Academic Article Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.
Academic Article Adults with cystic fibrosis in Portugal: A first step towards improvement.
Academic Article Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis.
Academic Article Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection.
Academic Article A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients.
Academic Article One-year safety and efficacy of tobramycin powder for inhalation in patients with cystic fibrosis.
Academic Article Short-term and long-term response to pulmonary exacerbation treatment in cystic fibrosis.
Academic Article Efficacy and safety of ivacaftor in patients with cystic fibrosis who have an Arg117His-CFTR mutation: a double-blind, randomised controlled trial.
Academic Article Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis.
Academic Article Optimising inhaled mannitol for cystic fibrosis in an adult population.
Academic Article Inhaled alpha1-proteinase inhibitor therapy in patients with cystic fibrosis.
Academic Article A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients.
Academic Article Testing two different doses of tiotropium Respimat? in cystic fibrosis: phase 2 randomized trial results.
Academic Article Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR.
Academic Article Rationalizing endpoints for prospective studies of pulmonary exacerbation treatment response in cystic fibrosis.
Academic Article Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research.
Academic Article Recovery of lung function following a pulmonary exacerbation in patients with cystic fibrosis and the G551D-CFTR mutation treated with ivacaftor.
Academic Article Pediatric and Adult Recommendations Vary for Sibling Testing in Cystic Fibrosis.
Academic Article ECFS best practice guidelines: the 2018 revision.
Academic Article Standardized Treatment of Pulmonary Exacerbations (STOP) study: Physician treatment practices and outcomes for individuals with cystic fibrosis with pulmonary Exacerbations.
Academic Article Standardized Treatment of Pulmonary Exacerbations (STOP) study: Observations at the initiation of intravenous antibiotics for cystic fibrosis pulmonary exacerbations.
Academic Article Predictors of pulmonary exacerbation treatment in cystic fibrosis.
Academic Article Antimicrobial resistance in cystic fibrosis: A Delphi approach to defining best practices.
Academic Article Safety and efficacy of lenabasum in a phase 2 randomized, placebo-controlled trial in adults with cystic fibrosis.
Academic Article Amikacin Liposome Inhalation Suspension for Mycobacterium avium Complex Lung Disease: A 12-Month Open-Label Extension Clinical Trial.
Academic Article Ototoxicity in cystic fibrosis patients receiving intravenous tobramycin for acute pulmonary exacerbation: Ototoxicity following tobramycin treatment.
Academic Article Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study.
Academic Article Changes in symptom scores as a potential clinical endpoint for studies of cystic fibrosis pulmonary exacerbation treatment.
Academic Article Efficacy and safety of inhaled dry-powder mannitol in adults with cystic fibrosis: An international, randomized controlled study.
Academic Article Amikacin Liposome Inhalation Suspension for Refractory Mycobacterium avium Complex Lung Disease: Sustainability and Durability of Culture Conversion and Safety of Long-term Exposure.
Academic Article Screening practices for nontuberculous mycobacteria at US cystic fibrosis centers.
Concept Transition to Adult Care
Academic Article Pulmonary Complications in Cystic Fibrosis: Past, Present, and Future: Adult Cystic Fibrosis Series.
Academic Article Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients.
Academic Article Disease burden in people with cystic fibrosis heterozygous for F508del and a minimal function mutation.
Academic Article A Randomized Clinical Trial of Antimicrobial Duration for Cystic Fibrosis Pulmonary Exacerbation Treatment.
Academic Article Improvements in anthropometric measures and gastrointestinal tolerance in patients with cystic fibrosis by using a digestive enzyme cartridge with overnight enteral nutrition.
Academic Article Association of site of treatment with clinical outcomes following intravenous antimicrobial treatment of a pulmonary exacerbation.
Academic Article Abdominal Surgical Procedures in Adult Patients With Cystic Fibrosis: What Are the Risks?
Academic Article Time-to-positivity of Mycobacterium avium complex in broth culture associates with culture conversion.
Academic Article Telehealth and CFTR modulators: Accelerating innovative models of cystic fibrosis care.
Academic Article Inhaled nitric oxide for adults with pulmonary non-tuberculous mycobacterial infection.
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