| Item Type | Name |
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Academic Article
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Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
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Academic Article
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Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism.
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Academic Article
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Effect of a genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production by C57BL6 Fas(lpr) mice.
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Academic Article
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Interferon regulatory factor-1 gene deletion decreases glomerulonephritis in MRL/lpr mice.
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Academic Article
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Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
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Academic Article
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Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms.
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Academic Article
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The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
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Academic Article
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Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage.
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Academic Article
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Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
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Academic Article
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The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice.
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Academic Article
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A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.
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Academic Article
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A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
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Academic Article
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
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Academic Article
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Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
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Academic Article
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Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis.
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Academic Article
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A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
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Academic Article
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Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice.
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Academic Article
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Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.
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Academic Article
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Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
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Academic Article
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
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Academic Article
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Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.
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Academic Article
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Gene expression profile reveals abnormalities of multiple signaling pathways in mesenchymal stem cell derived from patients with systemic lupus erythematosus.
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Academic Article
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Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
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Academic Article
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Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice.
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Academic Article
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Genetic control of inflammatory arthritis in congenic lpr mice.
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Academic Article
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Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
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Academic Article
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A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
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Academic Article
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Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
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Academic Article
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Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis.
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Academic Article
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Absence of functional alternative complement pathway alleviates lupus cerebritis.
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Academic Article
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
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Academic Article
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Impact of sphingosine kinase on inflammatory pathways in fibroblast-like synoviocytes.
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Academic Article
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Evaluation of TRAF6 in a large multiancestral lupus cohort.
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Academic Article
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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
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Academic Article
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Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis.
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Academic Article
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The transcription factor Fli-1 regulates monocyte, macrophage and dendritic cell development in mice.
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Academic Article
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Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
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Academic Article
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A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.
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Academic Article
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Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction.
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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TNF Receptor-Associated Factor 6
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Concept
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Transforming Growth Factor beta
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Concept
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Vascular Endothelial Growth Factor Receptor-1
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Concept
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Insulin-Like Growth Factor I
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Concept
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Complement Factor H
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Concept
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Core Binding Factor Alpha 3 Subunit
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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GATA1 Transcription Factor
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Concept
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Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Ikaros Transcription Factor
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Concept
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STAT4 Transcription Factor
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Concept
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Interferon Regulatory Factor-1
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Concept
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Complement Factor B
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Concept
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Rheumatoid Factor
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Concept
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B-Cell Activating Factor
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Concept
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Complement Factor D
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Concept
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Sp1 Transcription Factor
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Concept
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STAT1 Transcription Factor
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Academic Article
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Allogenic mesenchymal stem cell transplantation ameliorates nephritis in lupus mice via inhibition of B-cell activation.
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Academic Article
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A critical role of the transcription factor fli-1 in murine lupus development by regulation of interleukin-6 expression.
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Academic Article
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
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Academic Article
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Acetylation impacts Fli-1-driven regulation of granulocyte colony stimulating factor.
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Academic Article
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Adipose stem cells from chronic pancreatitis patients improve mouse and human islet survival and function.
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Academic Article
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B lymphocytes confer immune tolerance via cell surface GARP-TGF-? complex.
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Academic Article
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
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Academic Article
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Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
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Academic Article
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Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells.
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Academic Article
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Expression of GM-CSF Is Regulated by Fli-1 Transcription Factor, a Potential Drug Target.
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Academic Article
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Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB ? NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells.
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Academic Article
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Up-Regulated Interleukin-10 Induced by E2F Transcription Factor 2-MicroRNA-17-5p Circuitry in Extrafollicular Effector B Cells Contributes to Autoantibody Production in Systemic Lupus Erythematosus.
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Concept
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Tumor Necrosis Factor alpha-Induced Protein 3
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Academic Article
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Safety, immunological effects and clinical response in a phase I trial of umbilical cord mesenchymal stromal cells in patients with treatment refractory SLE.
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Academic Article
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals.
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