Item Type | Name |
Academic Article
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Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice.
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Academic Article
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Correlation of serum measures of nitric oxide production with lupus disease activity.
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Academic Article
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Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
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Academic Article
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Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice.
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Academic Article
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Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
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Academic Article
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Hemorrhage and thrombus formation in early experimental osteonecrosis.
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Academic Article
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Peroxisome proliferator-activated receptor gamma agonists: potential use for treating chronic inflammatory diseases.
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Academic Article
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Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-toluamide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel.
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Academic Article
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Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
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Academic Article
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Prospective measure of serum 3-nitrotyrosine levels in systemic lupus erythematosus: correlation with disease activity.
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Academic Article
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Nitric oxide induces apoptosis in spleen lymphocytes from MRL/lpr mice.
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Academic Article
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Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism.
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Academic Article
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Modulation of renal disease in MRL/lpr mice by suberoylanilide hydroxamic acid.
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Academic Article
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CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States.
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Academic Article
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Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype.
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Academic Article
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New therapies and preventive strategies to treat and minimize damage in lupus.
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Academic Article
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Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells.
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Academic Article
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Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms.
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Academic Article
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The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
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Academic Article
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Ets factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytes.
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Academic Article
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Sociodemographic associations with early disease damage in patients with systemic lupus erythematosus.
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Academic Article
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Association of serum nitrate and nitrite levels with longitudinal assessments of disease activity and damage in systemic lupus erythematosus and lupus nephritis.
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Academic Article
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Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
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Academic Article
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A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
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Academic Article
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The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
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Academic Article
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Common variants within MECP2 confer risk of systemic lupus erythematosus.
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Academic Article
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Two aspects of the clinical and humanistic burden of systemic lupus erythematosus: mortality risk and quality of life early in the course of disease.
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Academic Article
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Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse.
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Academic Article
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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice.
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Academic Article
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Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease.
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Academic Article
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A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
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Academic Article
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Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
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Academic Article
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
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Academic Article
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Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
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Academic Article
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Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing.
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Academic Article
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Identification of new SLE-associated genes with a two-step Bayesian study design.
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Academic Article
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Evaluation of C1q genomic region in minority racial groups of lupus.
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Academic Article
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A polymorphism within IL21R confers risk for systemic lupus erythematosus.
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Academic Article
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ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry.
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Academic Article
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Decreased expression of Fli-1 in bone marrow-derived haematopoietic cells significantly affects disease development in Murphy Roths Large/lymphoproliferation (MRL/lpr) mice.
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Academic Article
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The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
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Academic Article
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A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
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Academic Article
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A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis.
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Academic Article
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International consensus for a definition of disease flare in lupus.
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Academic Article
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Use of genetic knockouts to modulate disease expression in a murine model of lupus, MRL/lpr mice.
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Academic Article
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
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Academic Article
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Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.
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Academic Article
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The United States to Africa lupus prevalence gradient revisited.
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Academic Article
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Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
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Academic Article
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The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.
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Academic Article
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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
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Academic Article
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Mechanisms of tissue injury in lupus nephritis.
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Academic Article
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A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
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Academic Article
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Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
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Academic Article
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Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.
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Academic Article
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Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
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Academic Article
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Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
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Academic Article
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Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans.
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Academic Article
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Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity.
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Academic Article
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
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Academic Article
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Effect of genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production and renal disease in MRL/lpr mice.
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Academic Article
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
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Academic Article
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PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
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Academic Article
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Genetic control of inflammatory arthritis in congenic lpr mice.
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Academic Article
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Acute gouty arthritis and intravenous nitroglycerin.
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Academic Article
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Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
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Academic Article
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Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
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Academic Article
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Retroperitoneal fibrosis. A true connective tissue disease.
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Academic Article
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Systemic lupus erythematosus. Diagnosis and treatment.
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Academic Article
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Effect of late modulation of nitric oxide production on murine lupus.
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Academic Article
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Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus.
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Academic Article
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Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States.
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Academic Article
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Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
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Academic Article
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N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus.
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Academic Article
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Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2.
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Academic Article
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Immunological and hematological effects observed in B6C3F1 mice exposed to JP-8 jet fuel for 14 days.
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Academic Article
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Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.
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Academic Article
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A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
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Academic Article
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Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
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Academic Article
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Genomic view of systemic autoimmunity in MRLlpr mice.
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Academic Article
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The biology of nitric oxide and other reactive intermediates in systemic lupus erythematosus.
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Academic Article
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Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
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Academic Article
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Role for Msh5 in the regulation of Ig class switch recombination.
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Academic Article
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Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus.
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Academic Article
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Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
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Academic Article
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
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Academic Article
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Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ mice.
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Academic Article
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Inducible nitric oxide synthase inhibitor SD-3651 reduces proteinuria in MRL/lpr mice deficient in the NOS2 gene.
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Academic Article
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Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
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Academic Article
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Estrogen receptors in immunity and autoimmunity.
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Academic Article
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Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.
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Academic Article
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The lupus family registry and repository.
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Academic Article
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Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
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Academic Article
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Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
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Academic Article
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Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
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Academic Article
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The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
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Academic Article
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Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
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Academic Article
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Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
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Academic Article
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Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
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Academic Article
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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
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Academic Article
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Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
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Academic Article
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Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
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Academic Article
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Evaluation of TRAF6 in a large multiancestral lupus cohort.
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Academic Article
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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
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Academic Article
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Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
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Academic Article
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Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
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Academic Article
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Retroperitoneal fibrosis. The forgotten connective tissue disease.
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Academic Article
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
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Academic Article
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MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
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Academic Article
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
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Academic Article
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Riboflavin-responsive multiple acyl coenzyme A dehydrogenase deficiency presenting as a proximal myopathy in a young adult.
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Academic Article
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The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.
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Academic Article
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Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
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Academic Article
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Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
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Academic Article
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Detection of glomerular-binding immune elements in murine lupus using a tissue-based ELISA.
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Academic Article
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A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.
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Concept
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Disease Models, Animal
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Concept
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Disease Progression
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Concept
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Kidney Diseases
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Concept
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Joint Diseases
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Concept
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Disease Susceptibility
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Concept
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Chronic Disease
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Concept
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Genetic Diseases, X-Linked
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Concept
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Acute Disease
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Concept
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Genetic Predisposition to Disease
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Concept
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Lung Diseases
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Concept
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Graft vs Host Disease
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Concept
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Muscular Diseases
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Concept
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Autoimmune Diseases
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Concept
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Rheumatic Diseases
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Concept
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Immune Complex Diseases
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Academic Article
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NADPH oxidase and nitric oxide synthase-dependent superoxide production is increased in proliferative lupus nephritis.
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Academic Article
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
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Academic Article
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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
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Academic Article
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A critical role of the transcription factor fli-1 in murine lupus development by regulation of interleukin-6 expression.
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Academic Article
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Are microparticles the missing link between thrombosis and autoimmune diseases? Involvement in selected rheumatologic diseases.
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Academic Article
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Differential efficacy of human mesenchymal stem cells based on source of origin.
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Academic Article
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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
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Academic Article
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Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
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Academic Article
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
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Academic Article
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Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study.
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Academic Article
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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
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Academic Article
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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
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Academic Article
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X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sj?gren's Syndrome.
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Academic Article
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Early Ovariectomy Results in Reduced Numbers of CD11c+/CD11b+ Spleen Cells and Impacts Disease Expression in Murine Lupus.
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Academic Article
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Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
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Academic Article
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Toll-like receptor-mediated immune responses in intestinal macrophages; implications for mucosal immunity and autoimmune diseases.
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Academic Article
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Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.
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Academic Article
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Plasmacytoid dendritic cell distribution and maturation are altered in lupus prone mice prior to the onset of clinical disease.
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Academic Article
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A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.
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Academic Article
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B lymphocytes confer immune tolerance via cell surface GARP-TGF-? complex.
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Academic Article
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Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
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Academic Article
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Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
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Academic Article
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Intestinal macrophages in mucosal immunity and their role in systemic lupus erythematosus disease.
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Academic Article
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Novel mechanism for estrogen receptor alpha modulation of murine lupus.
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Academic Article
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Georgia Abortion Law and Our Commitment to Patients.
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Academic Article
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Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice.
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Academic Article
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Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic.
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Academic Article
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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
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Academic Article
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Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB ? NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells.
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Academic Article
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Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice.
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Academic Article
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Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages.
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Academic Article
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Safety and Efficacy of Mesenchymal Stromal Cells and Other Cellular Therapeutics in Rheumatic Diseases in 2022: A Review of What We Know So Far.
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Academic Article
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Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus.
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Academic Article
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COVID-19 mRNA vaccine BNT162b2 induces autoantibodies against type I interferons in a healthy woman.
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