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One or more keywords matched the following properties of Gilkeson, Gary
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keywords Autoimmune disease
keywords Ethnicity and Disease
keywords Rare Diseases
One or more keywords matched the following items that are connected to Gilkeson, Gary
Item TypeName
Academic Article Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice.
Academic Article Correlation of serum measures of nitric oxide production with lupus disease activity.
Academic Article Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Academic Article Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice.
Academic Article Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Academic Article Hemorrhage and thrombus formation in early experimental osteonecrosis.
Academic Article Peroxisome proliferator-activated receptor gamma agonists: potential use for treating chronic inflammatory diseases.
Academic Article Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-toluamide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel.
Academic Article Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
Academic Article Prospective measure of serum 3-nitrotyrosine levels in systemic lupus erythematosus: correlation with disease activity.
Academic Article Nitric oxide induces apoptosis in spleen lymphocytes from MRL/lpr mice.
Academic Article Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism.
Academic Article Modulation of renal disease in MRL/lpr mice by suberoylanilide hydroxamic acid.
Academic Article CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States.
Academic Article Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype.
Academic Article New therapies and preventive strategies to treat and minimize damage in lupus.
Academic Article Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells.
Academic Article Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms.
Academic Article The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Academic Article Ets factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytes.
Academic Article Sociodemographic associations with early disease damage in patients with systemic lupus erythematosus.
Academic Article Association of serum nitrate and nitrite levels with longitudinal assessments of disease activity and damage in systemic lupus erythematosus and lupus nephritis.
Academic Article Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
Academic Article A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
Academic Article The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
Academic Article Common variants within MECP2 confer risk of systemic lupus erythematosus.
Academic Article Two aspects of the clinical and humanistic burden of systemic lupus erythematosus: mortality risk and quality of life early in the course of disease.
Academic Article Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse.
Academic Article The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice.
Academic Article Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease.
Academic Article A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Academic Article Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
Academic Article High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Academic Article Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
Academic Article Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing.
Academic Article Identification of new SLE-associated genes with a two-step Bayesian study design.
Academic Article Evaluation of C1q genomic region in minority racial groups of lupus.
Academic Article A polymorphism within IL21R confers risk for systemic lupus erythematosus.
Academic Article ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry.
Academic Article Decreased expression of Fli-1 in bone marrow-derived haematopoietic cells significantly affects disease development in Murphy Roths Large/lymphoproliferation (MRL/lpr) mice.
Academic Article The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
Academic Article A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Academic Article A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis.
Academic Article International consensus for a definition of disease flare in lupus.
Academic Article Use of genetic knockouts to modulate disease expression in a murine model of lupus, MRL/lpr mice.
Academic Article Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
Academic Article Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.
Academic Article The United States to Africa lupus prevalence gradient revisited.
Academic Article Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
Academic Article The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.
Academic Article IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
Academic Article Mechanisms of tissue injury in lupus nephritis.
Academic Article A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Academic Article Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
Academic Article Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.
Academic Article Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
Academic Article Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans.
Academic Article Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity.
Academic Article A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Academic Article Effect of genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production and renal disease in MRL/lpr mice.
Academic Article Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
Academic Article PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
Academic Article Genetic control of inflammatory arthritis in congenic lpr mice.
Academic Article Acute gouty arthritis and intravenous nitroglycerin.
Academic Article Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
Academic Article Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
Academic Article Retroperitoneal fibrosis. A true connective tissue disease.
Academic Article Systemic lupus erythematosus. Diagnosis and treatment.
Academic Article Effect of late modulation of nitric oxide production on murine lupus.
Academic Article Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus.
Academic Article Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States.
Academic Article Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
Academic Article N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus.
Academic Article Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2.
Academic Article Immunological and hematological effects observed in B6C3F1 mice exposed to JP-8 jet fuel for 14 days.
Academic Article Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.
Academic Article A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Academic Article Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
Academic Article Genomic view of systemic autoimmunity in MRLlpr mice.
Academic Article The biology of nitric oxide and other reactive intermediates in systemic lupus erythematosus.
Academic Article Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
Academic Article Role for Msh5 in the regulation of Ig class switch recombination.
Academic Article Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus.
Academic Article Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ mice.
Academic Article Inducible nitric oxide synthase inhibitor SD-3651 reduces proteinuria in MRL/lpr mice deficient in the NOS2 gene.
Academic Article Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
Academic Article Estrogen receptors in immunity and autoimmunity.
Academic Article Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.
Academic Article The lupus family registry and repository.
Academic Article Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
Academic Article Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
Academic Article Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Academic Article The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
Academic Article Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
Academic Article Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
Academic Article Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Academic Article Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Academic Article Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Academic Article Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
Academic Article Evaluation of TRAF6 in a large multiancestral lupus cohort.
Academic Article Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
Academic Article Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
Academic Article Retroperitoneal fibrosis. The forgotten connective tissue disease.
Academic Article Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Academic Article MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
Academic Article Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
Academic Article Riboflavin-responsive multiple acyl coenzyme A dehydrogenase deficiency presenting as a proximal myopathy in a young adult.
Academic Article The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.
Academic Article Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
Academic Article Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
Academic Article Detection of glomerular-binding immune elements in murine lupus using a tissue-based ELISA.
Academic Article A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.
Concept Disease Models, Animal
Concept Disease Progression
Concept Kidney Diseases
Concept Joint Diseases
Concept Disease Susceptibility
Concept Chronic Disease
Concept Genetic Diseases, X-Linked
Concept Acute Disease
Concept Genetic Predisposition to Disease
Concept Lung Diseases
Concept Graft vs Host Disease
Concept Muscular Diseases
Concept Autoimmune Diseases
Concept Rheumatic Diseases
Concept Immune Complex Diseases
Academic Article NADPH oxidase and nitric oxide synthase-dependent superoxide production is increased in proliferative lupus nephritis.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
Academic Article A critical role of the transcription factor fli-1 in murine lupus development by regulation of interleukin-6 expression.
Academic Article Are microparticles the missing link between thrombosis and autoimmune diseases? Involvement in selected rheumatologic diseases.
Academic Article Differential efficacy of human mesenchymal stem cells based on source of origin.
Academic Article The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
Academic Article Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Academic Article Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study.
Academic Article Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
Academic Article X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sj?gren's Syndrome.
Academic Article Early Ovariectomy Results in Reduced Numbers of CD11c+/CD11b+ Spleen Cells and Impacts Disease Expression in Murine Lupus.
Academic Article Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Academic Article Toll-like receptor-mediated immune responses in intestinal macrophages; implications for mucosal immunity and autoimmune diseases.
Academic Article Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.
Academic Article Plasmacytoid dendritic cell distribution and maturation are altered in lupus prone mice prior to the onset of clinical disease.
Academic Article A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.
Academic Article B lymphocytes confer immune tolerance via cell surface GARP-TGF-? complex.
Academic Article Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
Academic Article Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Academic Article Intestinal macrophages in mucosal immunity and their role in systemic lupus erythematosus disease.
Academic Article Novel mechanism for estrogen receptor alpha modulation of murine lupus.
Academic Article Georgia Abortion Law and Our Commitment to Patients.
Academic Article Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice.
Academic Article Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic.
Academic Article Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
Academic Article Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB ? NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells.
Academic Article Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice.
Academic Article Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages.
Academic Article Safety and Efficacy of Mesenchymal Stromal Cells and Other Cellular Therapeutics in Rheumatic Diseases in 2022: A Review of What We Know So Far.
Academic Article Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus.
Academic Article COVID-19 mRNA vaccine BNT162b2 induces autoantibodies against type I interferons in a healthy woman.
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