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Hannun, Yusuf
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Academic Article Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase.
Academic Article Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells.
Academic Article Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.
Academic Article Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells.
Academic Article Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells.
Academic Article Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M.
Academic Article Neutral sphingomyelinase-2 mediates growth arrest by retinoic acid through modulation of ribosomal S6 kinase.
Academic Article Roles for sphingolipid biosynthesis in mediation of specific programs of the heat stress response determined through gene expression profiling.
Academic Article Identification of C18:1-phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast.
Academic Article Role for ceramide in cell cycle arrest.
Academic Article Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells.
Academic Article Golgi fragmentation is associated with ceramide-induced cellular effects.
Academic Article Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae.
Concept Cell Cycle Proteins
Concept Resting Phase, Cell Cycle
Concept Cell Cycle
Academic Article Activation of a retinoblastoma-protein-dependent pathway by sphingosine.
Academic Article Ceramide: an endogenous regulator of apoptosis and growth suppression.
Academic Article Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest.
Academic Article Functions of ceramide in coordinating cellular responses to stress.
Academic Article Dual role of ceramide in the control of apoptosis following IL-2 withdrawal.
Academic Article Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.
Academic Article New role for ceramide in the pheromone response.
Academic Article CHK1 regulates NF-?B signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles.
Academic Article Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.
Academic Article Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism.
Concept M Phase Cell Cycle Checkpoints
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  • Cell Cycle