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Hannun, Yusuf
One or more keywords matched the following items that are connected to Hannun, Yusuf
Item TypeName
Academic Article Molecular cloning and characterization of a human mitochondrial ceramidase.
Academic Article Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.
Academic Article Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells.
Academic Article Isc1 regulates sphingolipid metabolism in yeast mitochondria.
Academic Article Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice.
Academic Article Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells.
Academic Article Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.
Academic Article Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.
Academic Article Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas.
Academic Article A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria.
Academic Article Positively charged ceramide is a potent inducer of mitochondrial permeabilization.
Academic Article Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.
Academic Article ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae.
Academic Article AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.
Academic Article Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells.
Concept Mitochondria
Concept Mitochondria, Liver
Concept Mitochondria, Heart
Concept Mitochondria, Muscle
Academic Article Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.
Academic Article Critical determinants of mitochondria-associated neutral sphingomyelinase (MA-nSMase) for mitochondrial localization.
Academic Article Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5.
Academic Article Activation and localization of inositol phosphosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharomyces cerevisiae.
Academic Article The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae.
Academic Article A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury.
Academic Article Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death.
Academic Article Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism.
Academic Article Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.
Academic Article The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells.
Academic Article Sphingolipids and mitochondrial function in budding yeast.
Academic Article Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function.
Academic Article The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1.
Academic Article Decreased ceramide underlies mitochondrial dysfunction in Charcot-Marie-Tooth 2F.
Academic Article Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria.
Academic Article Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria.
Academic Article Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis.
Academic Article Mitochondria and ceramide: intertwined roles in regulation of apoptosis.
Academic Article BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome.
Academic Article Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation.
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  • Mitochondria