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One or more keywords matched the following items that are connected to Hannun, Yusuf
Item TypeName
Academic Article Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.
Academic Article Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
Academic Article Identification of a novel phosphatidic acid binding domain in protein phosphatase-1.
Academic Article Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.
Academic Article Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.
Academic Article Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.
Academic Article De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.
Academic Article Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B.
Academic Article Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner.
Academic Article Ceramide activates the stress-activated protein kinases.
Academic Article A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria.
Academic Article Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
Academic Article Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats.
Academic Article A role of sphingosine kinase 1 in head and neck carcinogenesis.
Concept Proto-Oncogene Protein c-ets-1
Concept Oncogene Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-myc
Concept Oncogene Protein v-akt
Concept Proto-Oncogene Proteins c-raf
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins
Academic Article Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors.
Academic Article Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction.
Academic Article Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor.
Academic Article Bcl-2 interrupts the ceramide-mediated pathway of cell death.
Academic Article prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.
Academic Article Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway.
Academic Article Upregulation of Bcl-2 and elevation of ceramide in Batten disease.
Academic Article Mechanisms of ceramide-mediated apoptosis.
Academic Article Regulation of membrane release in apoptosis.
Academic Article The role of ceramide in cell signaling.
Academic Article Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liver.
Academic Article Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism.
Academic Article AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.
Academic Article PKCa is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation.
Academic Article Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis.
Academic Article Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells.
Academic Article Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis.
Academic Article Ceramide in apoptosis: an overview and current perspectives.
Academic Article Protein Kinase C as a Therapeutic Target in Non-Small Cell Lung Cancer.
Academic Article Golgi maturation-dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3.
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  • Oncogene Proteins