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Hannun, Yusuf
One or more keywords matched the following items that are connected to Hannun, Yusuf
Item TypeName
Academic Article Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.
Academic Article Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
Academic Article Identification of a novel phosphatidic acid binding domain in protein phosphatase-1.
Academic Article Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.
Academic Article Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.
Academic Article Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.
Academic Article De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.
Academic Article Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B.
Academic Article Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner.
Academic Article Ceramide activates the stress-activated protein kinases.
Academic Article A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria.
Academic Article Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
Academic Article Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats.
Academic Article A role of sphingosine kinase 1 in head and neck carcinogenesis.
Concept Proto-Oncogene Protein c-ets-1
Concept Proto-Oncogenes
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins c-raf
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins
Academic Article Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors.
Academic Article Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction.
Academic Article Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor.
Academic Article Bcl-2 interrupts the ceramide-mediated pathway of cell death.
Academic Article prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.
Academic Article Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway.
Academic Article Upregulation of Bcl-2 and elevation of ceramide in Batten disease.
Academic Article Mechanisms of ceramide-mediated apoptosis.
Academic Article Regulation of membrane release in apoptosis.
Academic Article The role of ceramide in cell signaling.
Academic Article Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism.
Academic Article AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.
Academic Article PKCa is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation.
Academic Article Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis.
Academic Article Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells.
Academic Article Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis.
Academic Article Ceramide in apoptosis: an overview and current perspectives.
Academic Article Protein Kinase C as a Therapeutic Target in Non-Small Cell Lung Cancer.
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  • Proto Oncogenes