Item Type | Name |
Academic Article
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The NMDA antagonist, dizocilpine, enhances cocaine reinforcement without influencing mesoaccumbens dopamine transmission.
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Academic Article
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A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants.
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Academic Article
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Expression of D1 receptor, D2 receptor, substance P and enkephalin messenger RNAs in the neurons projecting from the nucleus accumbens.
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Academic Article
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MDMA elicits behavioral and neurochemical sensitization in rats.
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Academic Article
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Neuroadaptations involved in amphetamine and cocaine addiction.
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Academic Article
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Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment.
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Academic Article
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Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine.
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Academic Article
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Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area.
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Academic Article
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Calcium-mediated second messengers modulate the expression of behavioral sensitization to cocaine.
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Academic Article
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Dopamine depletion reorganizes projections from the nucleus accumbens and ventral pallidum that mediate opioid-induced motor activity.
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Academic Article
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The regulation of dopamine transmission by metabotropic glutamate receptors.
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Academic Article
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Regional distribution and cellular localization of gamma-aminobutyric acid subtype 1 receptor mRNA in the rat brain.
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Academic Article
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Neural systems for behavioral activation and reward.
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Academic Article
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Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization.
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Academic Article
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Glutamatergic and dopaminergic afferents to the prefrontal cortex regulate spatial working memory in rats.
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Academic Article
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Apomorphine decreases extracellular GABA in the ventral pallidum of rats with 6-OHDA lesions in the nucleus accumbens.
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Academic Article
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Correlation between behavioral sensitization to cocaine and G protein ADP-ribosylation in the ventral tegmental area.
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Academic Article
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Cellular mechanisms of behavioral sensitization to drugs of abuse.
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Academic Article
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GABAA receptors containing alpha 1 and beta 2 subunits are mainly localized on neurons in the ventral pallidum.
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Academic Article
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Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction.
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Academic Article
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Context-specific enhancement of glutamate transmission by cocaine.
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Academic Article
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gamma-Aminobutyric acid and mu-opioid receptor localization and adaptation in the basal forebrain.
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Academic Article
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Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity.
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Academic Article
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The involvement of the mediodorsal nucleus of the thalamus and the midbrain extrapyramidal area in locomotion elicited from the ventral pallidum.
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Academic Article
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In vivo assessment of release and metabolism of dopamine in the ventrolateral striatum of awake rats following administration of dopamine D1 and D2 receptor agonists and antagonists.
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Academic Article
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Effect of microinjections of apamin into the A10 dopamine region of rats: a behavioral and neurochemical analysis.
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Academic Article
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Involvement of pallidothalamic circuitry in working memory.
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Academic Article
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Effect of acute and daily neurotensin and enkephalin treatments on extracellular dopamine in the nucleus accumbens.
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Academic Article
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Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer.
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Academic Article
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Repeated cocaine administration into the rat ventral tegmental area produces behavioral sensitization to a systemic cocaine challenge.
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Academic Article
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Expression of glutamate receptor subunit/subtype messenger RNAS for NMDAR1, GLuR1, GLuR2 and mGLuR5 by accumbal projection neurons.
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Academic Article
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The role of the nucleus accumbens in sensitization to drugs of abuse.
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Academic Article
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Interrupted expression of NAC-1 augments the behavioral responses to cocaine.
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Academic Article
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Involvement of the pallidal-thalamocortical circuit in adaptive behavior.
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Academic Article
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The monoamine neurons of the rat brain preferentially express a splice variant of alpha1B subunit of the N-type calcium channel.
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Academic Article
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A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
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Academic Article
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GABAergic and enkephalinergic regulation of locomotion in the ventral pallidum: involvement of the mesolimbic dopamine system.
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Academic Article
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Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum.
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Academic Article
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The temporal sequence of changes in gene expression by drugs of abuse.
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Academic Article
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Brain circuitry and the reinstatement of cocaine-seeking behavior.
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Academic Article
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GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine.
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Academic Article
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Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.
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Academic Article
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Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse.
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Academic Article
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AGS3: a G-Protein regulator of addiction-associated behaviors.
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Academic Article
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Nucleus accumbens Homer proteins regulate behavioral sensitization to cocaine.
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Academic Article
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Prefrontal group II metabotropic glutamate receptor activation decreases performance on a working memory task.
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Academic Article
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Elucidation of Homer 1a function in the nucleus accumbens using adenovirus gene transfer technology.
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Academic Article
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Metabotropic glutamate receptor regulation of extracellular glutamate levels in the prefrontal cortex.
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Academic Article
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Cystine/glutamate antiporter regulation of vesicular glutamate release.
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Academic Article
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Chronic ethanol consumption by C57BL/6 mice promotes tolerance to its interoceptive cues and increases extracellular dopamine, an effect blocked by naltrexone.
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Academic Article
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Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens.
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Academic Article
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Glutamate systems in cocaine addiction.
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Academic Article
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Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.
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Academic Article
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Dissociable roles for the dorsal and median raph? in the facilitatory effect of 5-HT1A receptor stimulation upon cocaine-induced locomotion and sensitization.
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Academic Article
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Impoverished rearing environment alters metabotropic glutamate receptor expression and function in the prefrontal cortex.
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Academic Article
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Homer proteins regulate sensitivity to cocaine.
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Academic Article
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Homer2 gene deletion in mice produces a phenotype similar to chronic cocaine treated rats.
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Academic Article
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Regulation of locomotor activity by metabotropic glutamate receptors in the nucleus accumbens and ventral tegmental area.
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Academic Article
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NAC-1 is a brain POZ/BTB protein that can prevent cocaine-induced sensitization in the rat.
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Academic Article
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Regulation of extracellular glutamate in the prefrontal cortex: focus on the cystine glutamate exchanger and group I metabotropic glutamate receptors.
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Academic Article
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Ethanol exposure decreases glutamate uptake in the nucleus accumbens.
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Academic Article
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Autoradiographic localization of delta opioid receptors within the mesocorticolimbic dopamine system using radioiodinated [2-D-penicillamine, 5-D-penicillamine]enkephalin (125I-DPDPE).
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Academic Article
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Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum.
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Academic Article
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Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.
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Academic Article
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Homer2 is necessary for EtOH-induced neuroplasticity.
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Academic Article
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The neural basis of addiction: a pathology of motivation and choice.
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Academic Article
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Homer isoforms differentially regulate cocaine-induced neuroplasticity.
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Academic Article
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Exciting inhibition in psychostimulant addiction.
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Academic Article
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Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies.
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Academic Article
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Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.
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Academic Article
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Development of an alcohol deprivation and escalation effect in C57BL/6J mice.
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Academic Article
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Effects of d-amphetamine injected into the nucleus accumbens on ethanol reinforced behavior.
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Academic Article
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Changes in gamma-aminobutyric acid, mu-opioid and neurotensin receptors in the accumbens-pallidal projection after discrete quinolinic acid lesions in the nucleus accumbens.
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Academic Article
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Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization.
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Academic Article
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NAC1 regulates the recruitment of the proteasome complex into dendritic spines.
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Academic Article
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Drug addiction as a pathology of staged neuroplasticity.
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Academic Article
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Microdialysis and the neurochemistry of addiction.
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Academic Article
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Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement.
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Academic Article
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Neuroplasticity in the mesolimbic dopamine system and cocaine addiction.
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Academic Article
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Locomotor behavior.
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Academic Article
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Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats.
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Academic Article
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Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens.
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Academic Article
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Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens.
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Academic Article
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Integrin expression is altered after acute and chronic cocaine.
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Academic Article
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Addiction as a pathology in prefrontal cortical regulation of corticostriatal habit circuitry.
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Academic Article
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Computational model of extracellular glutamate in the nucleus accumbens incorporates neuroadaptations by chronic cocaine.
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Academic Article
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Glutamate and reinstatement.
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Academic Article
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Enkephalinergic and GABAergic modulation of motor activity in the ventral pallidum.
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Academic Article
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The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.
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Academic Article
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Effects of 5-hydroxytryptophan on extracellular serotonin in the spinal cord of rats with experimental allergic encephalomyelitis.
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Academic Article
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Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens.
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Academic Article
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A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens.
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Academic Article
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The glutamate homeostasis hypothesis of addiction.
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Academic Article
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Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion.
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Academic Article
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Amphetamine lowers extracellular GABA concentration in the ventral pallidum.
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Academic Article
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Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats.
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Academic Article
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Neuroscience: Lack of inhibition leads to abuse.
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Academic Article
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Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking.
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Academic Article
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Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalon.
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Academic Article
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Substance K and substance P differentially modulate mesolimbic and mesocortical systems.
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Academic Article
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Substance P modulation of the mesolimbic dopamine system.
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Academic Article
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The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration.
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Academic Article
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Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction.
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Academic Article
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Sexual refractoriness and locomotion effects on brain monoamines in the male rat.
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Academic Article
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Molecular diffusion model of neurotransmitter homeostasis around synapses supporting gradients.
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Academic Article
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Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking.
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Academic Article
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Neuroadaptive changes in NMDAR1 gene expression after extinction of cocaine self-administration.
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Academic Article
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High sensitivity HPLC assay for GABA in brain dialysis studies.
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Academic Article
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AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis.
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Academic Article
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Glutamatergic medications for the treatment of drug and behavioral addictions.
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Academic Article
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Similar effects of daily cocaine and stress on mesocorticolimbic dopamine neurotransmission in the rat.
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Academic Article
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Autoradiographic localization of mu-opioid and neurotensin receptors within the mesolimbic dopamine system.
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Academic Article
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A silent synapse-based mechanism for cocaine-induced locomotor sensitization.
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Academic Article
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Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes.
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Academic Article
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Translating glutamate: from pathophysiology to treatment.
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Academic Article
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Integrins modulate relapse to cocaine-seeking.
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Academic Article
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Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.
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Academic Article
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Optogenetic inhibition of cocaine seeking in rats.
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Academic Article
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Stress-induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei.
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Academic Article
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Nucleus Accumbens 1, a Pox virus and Zinc finger/Bric-a-brac Tramtrack Broad protein binds to TAR DNA-binding protein 43 and has a potential role in Amyotrophic Lateral Sclerosis.
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Academic Article
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Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation.
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Academic Article
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Forebrain astroglial plasticity is induced following withdrawal from repeated cocaine administration.
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Academic Article
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Blockade of enkephalinergic and GABAergic mediated locomotion in the nucleus accumbens by muscimol in the ventral pallidum.
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Academic Article
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Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking.
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Academic Article
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A comparison of 5-hydroxytryptophan effects on rat lumbar spinal cord serotonin release and monosynaptic response amplitude.
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Academic Article
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The acute histopathology of MPTP in the mouse CNS.
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Academic Article
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Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. I. Behavioral characterization.
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Academic Article
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Endogenous enkephalin modulation of dopamine neurons in ventral tegmental area.
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Academic Article
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Behavioral and neurochemical effects of acute and daily cocaine administration in rats.
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Academic Article
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The effect of cholinergic stimulation in the nucleus accumbens on locomotor behavior.
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Academic Article
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Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release.
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Academic Article
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Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.
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Academic Article
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Enkephalin release into the ventral tegmental area in response to stress: modulation of mesocorticolimbic dopamine.
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Academic Article
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Cholecystokinin-induced suppression of locomotion is attenuated in capsaicin pretreated rats.
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Academic Article
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Dopamine microinjection into the nucleus accumbens: correlation between metabolism and behavior.
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Academic Article
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Behavioral and neurochemical effect of daily injection with neurotensin into the ventral tegmental area.
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Academic Article
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Thyrotropin-releasing hormone: neurogenesis of actions in the pentobarbital narcotized rat.
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Academic Article
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Interactions of neurotensin with brain dopamine systems.
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Academic Article
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Behavioral effects of hypothalamic hypophysiotropic hormones, neurotensin, substance P and other neuropeptides.
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Academic Article
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Influence of cholecystokinin on central monoaminergic pathways.
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Academic Article
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Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat.
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Academic Article
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Neurotensin neurons in the ventral tegmental area project to the medial nucleus accumbens.
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Academic Article
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Neuroanatomical dissociation of thyrotropin-releasing hormone induced shaking behavior and thermogenic mechanisms.
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Academic Article
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Effect of septohippocampal lesions on thyrotropin-releasing hormone antagonism of pentobarbital narcosis.
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Academic Article
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Neuroanatomical sites of action of neurotensin.
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Academic Article
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Homer1 proteins and AMPA receptors modulate cocaine-induced behavioural plasticity.
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Academic Article
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Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens.
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Academic Article
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Histamine-induced arousal in the conscious and pentobarbital-pretreated rat.
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Academic Article
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Antinociception after microinjection of neurotensin into the central amygdaloid nucleus of the rat.
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Academic Article
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Topography and functional role of dopaminergic projections from the ventral mesencephalic tegmentum to the ventral pallidum.
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Academic Article
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Involvement of dopamine and excitatory amino acid transmission in novelty-induced motor activity.
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Academic Article
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D1 receptors modulate glutamate transmission in the ventral tegmental area.
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Academic Article
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GABAergic projection from the ventral pallidum and globus pallidus to the subthalamic nucleus.
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Academic Article
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Effects of cocaine and footshock stress on extracellular dopamine levels in the medial prefrontal cortex.
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Academic Article
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Possible transduction mechanisms mediating the acute and sensitized response to neurotensin in the ventral tegmental area.
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Academic Article
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Neuroanatomy and neurochemical mechanisms of time-dependent sensitization.
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Academic Article
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Selective activation of dopamine transmission in the shell of the nucleus accumbens by stress.
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Academic Article
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Pertussis toxin in the A10 region increases dopamine synthesis and metabolism.
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Academic Article
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Methylenedioxymethamphetamine depresses glutamate-evoked neuronal firing and increases extracellular levels of dopamine and serotonin in the nucleus accumbens in vivo.
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Academic Article
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Blockade of neurotensin-induced motor activity by inhibition of protein kinase.
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Academic Article
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Microinjection of the D2 agonist quinpirole into the A10 dopamine region blocks amphetamine-, but not cocaine-stimulated motor activity.
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Academic Article
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The relationship between MRNA levels and the locomotor response to novelty.
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Academic Article
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Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine.
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Academic Article
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Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus.
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Academic Article
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Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya.
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Academic Article
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Dopamine and endogenous opioid regulation of picrotoxin-induced locomotion in the ventral pallidum after dopamine depletion in the nucleus accumbens.
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Academic Article
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Chronic haloperidol does not alter G protein alpha-subunit levels in rats.
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Academic Article
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Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals.
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Academic Article
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High and low behavioral response to novelty is associated with differences in neurotensin and substance P content.
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Academic Article
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Repeated intra-ventral tegmental area administration of SKF-38393 induces behavioral and neurochemical sensitization to a subsequent cocaine challenge.
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Academic Article
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beta-adrenergic antagonism alters the behavioral and neurochemical responses to cocaine.
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Academic Article
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Repeated cocaine modifies the mechanism by which amphetamine releases dopamine.
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Academic Article
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Repeated daily cocaine alters subsequent cocaine-induced increase of extracellular dopamine in the medial prefrontal cortex.
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Academic Article
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Glutamate transmission and addiction to cocaine.
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Academic Article
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N-acetyl cysteine-induced blockade of cocaine-induced reinstatement.
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Academic Article
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Evidence for a relationship between Group 1 mGluR hypofunction and increased cocaine and ethanol sensitivity in Homer2 null mutant mice.
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Academic Article
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Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes.
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Academic Article
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Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior.
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Academic Article
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Possible role for G-proteins in behavioral sensitization to cocaine.
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Academic Article
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Sensitization to cocaine produced by injection of pertussis toxin into the A10 dopamine region.
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Academic Article
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Dopamine regulation of extracellular glutamate in the nucleus accumbens.
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Academic Article
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NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration.
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Academic Article
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The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance.
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Academic Article
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Last call for adenosine transporters.
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Academic Article
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Novel ideas about novelty. Commentary on Badiani and Robinson drug-induced neurobehavioral plasticity: the role of environmental context.
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Academic Article
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Sensitization to psychostimulants and stress after injection of pertussis toxin into the A10 dopamine region.
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Academic Article
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Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission.
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Academic Article
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Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking.
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Academic Article
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A comparison of axonal and somatodendritic dopamine release using in vivo dialysis.
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Academic Article
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Activity-dependent subcellular localization of NAC1.
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Academic Article
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How do we determine which drug-induced neuroplastic changes are important?
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Academic Article
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Contribution of dihydro-beta-erythroidine sensitive nicotinic acetylcholine receptors in the ventral tegmental area to cocaine-induced behavioral sensitization in rats.
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Academic Article
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Distinct roles for different Homer1 isoforms in behaviors and associated prefrontal cortex function.
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Academic Article
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Cocaine increases actin cycling: effects in the reinstatement model of drug seeking.
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Academic Article
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Orexin: a gatekeeper of addiction.
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Academic Article
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Dopaminergic involvement in locomotion elicited from the ventral pallidum/substantia innominata.
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Academic Article
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The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats.
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Academic Article
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Homer proteins: implications for neuropsychiatric disorders.
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Academic Article
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Specificity in the projection patterns of accumbal core and shell in the rat.
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Academic Article
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Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.
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Academic Article
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Autoradiographic localization of angiotensin II receptor binding sites on noradrenergic neurons of the locus coeruleus of the rat.
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Academic Article
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Long-term neuroadaptations produced by withdrawal from repeated cocaine treatment: role of dopaminergic receptors in modulating cortical excitability.
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Academic Article
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Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cues.
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Academic Article
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Animal models and brain circuits in drug addiction.
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Academic Article
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Modulation of A10 dopamine neurons by gamma-aminobutyric acid agonists.
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Academic Article
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N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking.
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Academic Article
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Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response.
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Academic Article
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Opposing roles for the ventral prefrontal cortex and the basolateral amygdala on the spontaneous recovery of cocaine-seeking in rats.
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Academic Article
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Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity.
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Academic Article
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Glutamate release in the nucleus accumbens core is necessary for heroin seeking.
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Academic Article
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Neuropharmacology of addiction--setting the scene.
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Academic Article
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The glutamatergic projection from the prefrontal cortex to the nucleus accumbens core is required for cocaine-induced decreases in ventral pallidal GABA.
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Academic Article
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Brain norepinephrine rediscovered in addiction research.
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Academic Article
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Glutamate transmission in addiction.
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Academic Article
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Confused about NMDA and addiction? Targeted knockouts provide answers and new questions.
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Academic Article
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Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats.
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Academic Article
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Neuronal pentraxins modulate cocaine-induced neuroadaptations.
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Academic Article
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Neuroscience: Brain's defence against cocaine.
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Academic Article
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Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling.
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Academic Article
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Effects of training and withdrawal periods on heroin seeking induced by conditioned cue in an animal of model of relapse.
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Academic Article
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The role of cystine-glutamate exchange in nicotine dependence in rats and humans.
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Academic Article
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N-Acetylcysteine reverses cocaine-induced metaplasticity.
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Academic Article
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Perspective: the manifest destiny of cocaine research.
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Academic Article
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Altered dendritic spine plasticity in cocaine-withdrawn rats.
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Academic Article
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Preliminary evidence for a cocaine-induced embryopathy in mice.
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Academic Article
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Extinction circuits for fear and addiction overlap in prefrontal cortex.
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Academic Article
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Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking.
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Academic Article
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Substance K and substance P in the ventral tegmental area.
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Academic Article
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Inhibition of actin polymerization prevents cocaine-induced changes in spine morphology in the nucleus accumbens.
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Academic Article
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Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking.
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Academic Article
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Using glutamate homeostasis as a target for treating addictive disorders.
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Academic Article
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Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse.
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Academic Article
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Harnessing neuroplasticity for clinical applications.
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Academic Article
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Drug wanting: behavioral sensitization and relapse to drug-seeking behavior.
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Academic Article
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Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity.
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Academic Article
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Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice.
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Academic Article
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Use of vivo-morpholinos for control of protein expression in the adult rat brain.
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Academic Article
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The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine.
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Academic Article
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Neural circuit competition in cocaine-seeking: roles of the infralimbic cortex and nucleus accumbens shell.
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Academic Article
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Role of mGluR5 neurotransmission in reinstated cocaine-seeking.
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Academic Article
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The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.
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Academic Article
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Ceftriaxone normalizes nucleus accumbens synaptic transmission, glutamate transport, and export following cocaine self-administration and extinction training.
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Academic Article
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Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration.
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Academic Article
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Forgiving the sins of the fathers.
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Academic Article
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Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens.
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Academic Article
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Somatodendritic release of endogenous dopamine: in vivo dialysis in the A10 dopamine region.
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Academic Article
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Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
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Academic Article
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Reinstatement of nicotine seeking is mediated by glutamatergic plasticity.
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Academic Article
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A catecholaminergic projection from the ventral tegmental area to the diagonal band of Broca: modulation by neurotensin.
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Academic Article
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Microinjection of neurotensin into the ventral tegmental area produces hypothermia: evaluation of dopaminergic mediation.
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Academic Article
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Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
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Academic Article
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Sensitization occurs to the locomotor effects of morphine and the specific mu opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens.
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Academic Article
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Enkephalin modulation of A10 dopamine neurons: a role in dopamine sensitization.
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Academic Article
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Interaction between thyrotropin-releasing hormone and the mesolimbic dopamine system.
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Academic Article
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Behavioral cross-sensitization between cocaine and enkephalin in the A10 dopamine region.
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Academic Article
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Neurochemical and behavioral effects of corticotropin-releasing factor in the ventral tegmental area of the rat.
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Academic Article
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Sensitization to repeated morphine injection in the rat: possible involvement of A10 dopamine neurons.
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Academic Article
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Cross-sensitization between foot shock stress and enkephalin-induced motor activity.
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Academic Article
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Neuromedin N mimics the actions of neurotensin in the ventral tegmental area but not in the nucleus accumbens.
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Academic Article
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Mesolimbic dopamine lesions produce an augmented behavioral response to enkephalin.
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Academic Article
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Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. II. Involvement of the mesolimbic dopamine system.
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Academic Article
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Neurotensin in the ventromedial mesencephalon of the rat: anatomical and functional considerations.
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Academic Article
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Possible involvement of serotonergic neurotransmission in neurotensin but not morphine analgesia.
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Academic Article
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Failure of muscarinic blockade to antagonize analepsis induced by thyrotropin-releasing hormone and MK-771 in the rat.
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Academic Article
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Substance P modulation of dopamine in the nucleus accumbens.
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Academic Article
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Evidence for interactions of endogenous peptides with the mesolimbic dopamine system.
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Academic Article
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Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity.
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Academic Article
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Neurotensin microinjection into the nucleus accumbens antagonizes dopamine-induced increase in locomotion and rearing.
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Academic Article
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Bombesin-induced locomotor hyperactivity: evaluation of the involvement of the mesolimbic dopamine system.
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Academic Article
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Neuroanatomical site specific modulation of spontaneous motor activity by neurotensin.
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Academic Article
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Increase in spontaneous motor activity following infusion of neurotensin into the ventral tegmental area.
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Academic Article
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Effect of inhibiting enkephalin catabolism in the VTA on motor activity and extracellular dopamine.
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Academic Article
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Response to intracerebral administration of cerebrospinal fluid in the pentobarbital pretreated rat.
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Academic Article
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Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
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Academic Article
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Autoradiographic localization of gamma-aminobutyric acidA receptors within the ventral tegmental area.
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Academic Article
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GABA and enkephalin projection from the nucleus accumbens and ventral pallidum to the ventral tegmental area.
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Academic Article
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Modulation of extracellular gamma-aminobutyric acid in the ventral pallidum using in vivo microdialysis.
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Academic Article
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Dopamine depletion produces augmented behavioral responses to a mu-, but not a delta-opioid receptor agonist in the nucleus accumbens: lack of a role for receptor upregulation.
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Academic Article
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Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study.
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Academic Article
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Cocaine alters glutamic acid decarboxylase differentially in the nucleus accumbens core and shell.
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Academic Article
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Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens.
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Academic Article
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The role of mesoaccumbens--pallidal circuitry in novelty-induced behavioral activation.
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Academic Article
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Interactions between dopamine and excitatory amino acids in behavioral sensitization to psychostimulants.
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Academic Article
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Behavioral and neurochemical sensitization following cocaine self-administration.
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Academic Article
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Individual differences in behavior following amphetamine, GBR-12909, or apomorphine but not SKF-38393 or quinpirole.
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Academic Article
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Neural substrate of sensitization to psychostimulants.
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Academic Article
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Individual locomotor response to novelty predicts selective alterations in D1 and D2 receptors and mRNAs.
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Academic Article
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A topographically organized gamma-aminobutyric acid projection from the ventral pallidum to the nucleus accumbens in the rat.
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Academic Article
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Neurotransmitter regulation of dopamine neurons in the ventral tegmental area.
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Academic Article
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Patterns of glucose use after bicuculline-induced convulsions in relationship to gamma-aminobutyric acid and mu-opioid receptors in the ventral pallidum--functional markers for the ventral pallidum.
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Academic Article
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Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.
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Academic Article
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Robustness of G protein changes in cocaine sensitization shown with immunoblotting.
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Academic Article
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Dopamine depletion augments endogenous opioid-induced locomotion in the nucleus accumbens using both mu 1 and delta opioid receptors.
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Academic Article
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Thyrotropin-releasing hormone: central site of action in antagonism of pentobarbital narcosis.
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Academic Article
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Sensitization to stress and psychostimulants. Involvement of dopamine transmission versus the HPA axis.
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Academic Article
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Involvement of the ventral tegmental area in locomotion elicited from the nucleus accumbens or ventral pallidum.
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Academic Article
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Substance P in the ventral pallidum: projection from the ventral striatum, and electrophysiological and behavioral consequences of pallidal substance P.
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Academic Article
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Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization.
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Academic Article
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Effect of adrenalectomy on the initiation and expression of cocaine-induced sensitization.
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Academic Article
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The mediodorsal nucleus of the thalamus in rats--II. Behavioral and neurochemical effects of GABA agonists.
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Academic Article
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The mediodorsal nucleus of the thalamus in rats--I. forebrain gabaergic innervation.
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Academic Article
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Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat.
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Academic Article
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Expression of D1 receptor mRNA in projections from the forebrain to the ventral tegmental area.
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Concept
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Disease Models, Animal
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Concept
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Animals, Newborn
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Concept
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Animals
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Concept
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Behavior, Animal
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Concept
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Animals, Genetically Modified
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Concept
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Pregnancy, Animal
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Concept
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Models, Animal
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Concept
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Sexual Behavior, Animal
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Academic Article
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Getting to the core of addiction: hatching the addiction egg.
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Academic Article
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Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors.
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Academic Article
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The rostral subcommissural ventral pallidum is a mix of ventral pallidal neurons and neurons from adjacent areas: an electrophysiological study.
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Academic Article
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Rapid, transient synaptic plasticity in addiction.
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Academic Article
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The story of glutamate in drug addiction and of N-acetylcysteine as a potential pharmacotherapy.
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Academic Article
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Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism.
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Academic Article
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Potential role of N-acetylcysteine in the management of substance use disorders.
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Academic Article
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Prelimbic cortex and ventral tegmental area modulate synaptic plasticity differentially in nucleus accumbens during cocaine-reinstated drug seeking.
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Academic Article
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Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum.
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Academic Article
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Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse.
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Academic Article
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Metabotropic glutamatergic receptors and their ligands in drug addiction.
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Academic Article
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a2d-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse.
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Academic Article
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Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases.
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Academic Article
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Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis.
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Academic Article
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More cocaine-more glutamate-more addiction.
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Academic Article
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Rapid, transient potentiation of dendritic spines in context-induced relapse to cocaine seeking.
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Academic Article
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The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis.
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Academic Article
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Glutamatergic mechanisms of comorbidity between acute stress and cocaine self-administration.
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Academic Article
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Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.
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Academic Article
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Signals from the Fourth Dimension Regulate Drug Relapse.
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Academic Article
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Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core.
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Academic Article
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Addiction-like Synaptic Impairments in Diet-Induced Obesity.
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Academic Article
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Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections.
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Academic Article
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Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking.
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Academic Article
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The tetrapartite synapse: Extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction.
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Academic Article
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Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior.
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Academic Article
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Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement.
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Academic Article
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Glutamate Transporter GLT-1 as a Therapeutic Target for Substance Use Disorders.
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Academic Article
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Cocaine Use Reverses Striatal Plasticity Produced During Cocaine Seeking.
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Academic Article
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The Direct and Indirect Pathways of the Nucleus Accumbens are not What You Think.
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Academic Article
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Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking.
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Academic Article
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Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking.
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Academic Article
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New vistas on cannabis use disorder.
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Academic Article
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Glutamate Transport: A New Bench to Bedside Mechanism for Treating Drug Abuse.
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Academic Article
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Accumbens Mechanisms for Cued Sucrose Seeking.
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Academic Article
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HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors.
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Academic Article
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Metaplasticity at the addicted tetrapartite synapse: A common denominator of drug induced adaptations and potential treatment target for addiction.
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Academic Article
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Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.
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Academic Article
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Accumbens nNOS Interneurons Regulate Cocaine Relapse.
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Academic Article
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Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior.
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Academic Article
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A Model of ?9-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens.
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Academic Article
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Accumbens brain-derived neurotrophic factor (BDNF) transmission inhibits cocaine seeking.
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Academic Article
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Drug Refraining and Seeking Potentiate Synapses on Distinct Populations of Accumbens Medium Spiny Neurons.
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Academic Article
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Targeting redox regulation to treat substance use disorder using N-acetylcysteine
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Academic Article
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Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking.
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Academic Article
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Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core.
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Academic Article
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Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking.
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Academic Article
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Extracellular Matrix Signaling Through ?3 Integrin Mediates Cocaine Cue-Induced Transient Synaptic Plasticity and Relapse.
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Academic Article
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N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse.
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Academic Article
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Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking.
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Academic Article
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Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking.
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Academic Article
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Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking.
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Academic Article
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The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors.
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Academic Article
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Understanding Addiction Using Animal Models.
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Academic Article
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N-acetylcysteine mitigates acute opioid withdrawal behaviors and CNS oxidative stress in neonatal rats.
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Academic Article
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Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum.
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Academic Article
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Relapse-Associated Transient Synaptic Potentiation Requires Integrin-Mediated Activation of Focal Adhesion Kinase and Cofilin in D1-Expressing Neurons.
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Academic Article
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Heroin Seeking and Extinction From Seeking Activate Matrix Metalloproteinases at Synapses on Distinct Subpopulations of Accumbens Cells.
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Academic Article
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Astrocytes as cellular mediators of cue reactivity in addiction.
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Academic Article
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Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core.
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Academic Article
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Circuit selectivity in drug versus natural reward seeking behaviors.
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Academic Article
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Long-term impact of acute restraint stress on heroin self-administration, reinstatement, and stress reactivity.
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Academic Article
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Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date.
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Academic Article
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Astrocytes in the ventral pallidum extinguish heroin seeking through GAT-3 upregulation and morphological plasticity at D1-MSN terminals.
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Academic Article
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Behavioral and accumbens synaptic plasticity induced by cues associated with restraint stress.
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Academic Article
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Assessing combined effects of varenicline and N-acetylcysteine on reducing nicotine seeking in rats.
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Academic Article
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Cannabinoid use is enhanced by stress and changes conditioned stress responses.
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Academic Article
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Drug versus non-drug behaviors: A dual-reward model of sex differences and neurobiological mechanisms in rats.
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Academic Article
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Astrocyte regulation of synaptic signaling in psychiatric disorders.
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Academic Article
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N-acetylcysteine improves impulse control and attenuates relapse-like alcohol intake in long-term drinking rats.
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Academic Article
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Novelty-induced locomotor behavior predicts heroin addiction vulnerability in male, but not female, rats.
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